Results 1-84 of 84 (Search time: 0.007 seconds).

Issue DateTitleAuthor(s)TypescopusWOSFulltext/Archive link
12019Synthesis and biological evaluation of anthra[1,9-cd]pyrazol-6(2H)-one scaffold derivatives as potential anticancer agentsChen T.-C.; Guh J.-H.; Hsu H.-W.; Chen C.-L.; Lee C.-C.; Wu C.-L.; Lee Y.-R.; JING-JER LIN ; Yu D.-S.; Huang H.-S.journal article22
22019Design, synthesis and biological evaluation of tetracyclic azafluorenone derivatives with topoisomerase I inhibitory properties as potential anticancer agentsChen T.-C.; Yu D.-S.; Chen S.-J.; Chen C.-L.; Lee C.-C.; Hsieh Y.-Y.; Chang L.-C.; Guh J.-H.; JING-JER LIN ; Huang H.-S.journal article44
32018A Low-Toxicity DNA-Alkylating N-Mustard-Quinoline Conjugate with Preferential Sequence Specificity Exerts Potent Antitumor Activity Against Colorectal CancerChen T.-L.; Lin Y.-W.; Chen Y.-B.; JING-JER LIN ; Su T.-L.; Shen C.-N.; Lee T.-C.journal article22
42017The serine protease inhibitor serpinB2 binds and stabilizes p21 in senescent cellsHsieh H.-H.; Chen Y.-C.; Jhan J.-R.; JING-JER LIN journal article1212
52017GATA3 interacts with and stabilizes HIF-1α to enhance cancer cell invasivenessLin M.-C.; JING-JER LIN ; Hsu C.-L.; Juan H.-F.; Lou P.-J.; Huang M.-C.journal article117
62016Modulation of yeast telomerase activity by Cdc13 and Est1 in vitroChen Y.-F.; Lu C.-Y.; Lin Y.-C.; Yu T.-Y.; Chang C.-P.; Li J.-R.; Li H.-W.; JING-JER LIN journal article21
72016Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validationChang L.-C.; Chen T.-C.; Chen S.-J.; Chen C.-L.; Lee C.-C.; Wu S.-H.; Yen Y.; Huang H.-S.; JING-JER LIN journal article01
82016Design, synthesis, and evaluation of cell permeable probes for protein kinasesHsu Y.-L.; Yang C.-C.; Chou T.-C.; Tai C.-H.; Chen L.-Y.; Fu S.-L.; JING-JER LIN ; Lo L.-C.journal article33
92016Multiple Pif1 helicases are required to sequentially disrupt G-quadruplex structure and unwind duplex DNALi J.-R.; Lu C.-Y.; JING-JER LIN ; Li H.-W.journal article22
102015Conformational transition of a hairpin structure to G-quadruplex within the WNT1 gene promoterKuo M.H.-J.; Wang Z.-F.; Tseng T.-Y.; Li M.-H.; Hsu S.-T.D.; JING-JER LIN ; Chang T.-C.journal article2627
112015Direct evidence of mitochondrial G-quadruplex DNA by using fluorescent anti-cancer agentsHuang W.-C.; Tseng T.-Y.; Chen Y.-T.; Chang C.-C.; Wang Z.-F.; Wang C.-L.; Hsu T.-N.; Li P.-T.; Chen C.-T.; JING-JER LIN ; Lou P.-J.; Chang T.-C.journal article5852
122015A fluorescent anti-cancer agent, 3,6-bis(1-methyl-4-vinylpyridinium) carbazole diiodide, stains g-quadruplexes in cells and inhibits tumor growthTseng T.-Y.; Chang C.-C.; JING-JER LIN ; Chang T.-C.journal article99
132015The addition of a spin column step in the telomeric repeat application protocol removes telomerase inhibitorsChen Y.-C.; Huang F.-C.; JING-JER LIN journal article37
142014Inhibition of cancer cell migration and invasion through suppressing the wnt1-mediating signal pathway by G-quadruplex structure stabilizersWang J.M.; Huang F.C.; Kuo M.H.-J.; Wang Z.-F.; Tseng T.-Y.; Chang L.-C.; Yen S.-J.; Chang T.-C.; JING-JER LIN journal article2524
152014Pif1 regulates telomere length by preferentially removing telomerase from long telomere endsLi J.-R.; Yu T.-Y.; Chien I.-C.; Lu C.-Y.; JING-JER LIN ; Li H.-W.journal article1616
162014Yin Yang 1 is a target of microRNA-34 family and contributes to gastric carcinogenesisWang A.-M.; Huang T.-T.; Hsu K.-W.; Huang K.-H.; Fang W.-L.; Yang M.-H.; Lo S.-S.; Chi C.-W.; JING-JER LIN ; Yeh T.-S.journal article5552
172014Telomeric transcripts stimulate telomere recombination to suppress senescence in cells lacking telomeraseYu T.-Y.; Kao Y.-W.; JING-JER LIN journal article7371
182013Aconitamide, a novel alkaloid from the roots of Aconitum carmichaeliLee T.-H.; Chen Y.-C.; Lee C.-K.; Chang H.-S.; Kuo C.-C.; Chao C.-Y.; JING-JER LIN ; Lo L.-C.; Kuo Y.-H.journal article4
192013Structure-based design, synthesis and evaluation of novel anthra[1,2-d]imidazole-6,11-dione derivatives as telomerase inhibitors and potential for cancer polypharmacologyChen C.-L.; Chang D.-M.; Chen T.-C.; Lee C.-C.; Hsieh H.-H.; Huang F.-C.; Huang K.-F.; Guh J.-H.; JING-JER LIN ; Huang H.-S.journal article2726
202013Development and evaluation of novel phosphotyrosine mimetic inhibitors targeting the Src homology 2 domain of signaling lymphocytic activation molecule (SLAM) associated proteinChu C.-Y.; Chang C.-P.; Chou Y.-T.; Handoko, Hu Y.-L.; Lo L.-C.; JING-JER LIN journal article11
212013Synthesis and evaluation of activity-based probes carrying a 5′-fluorosulfonylbenzoyl adenosine moiety for protein kinasesHsu Y.-L.; Yang C.-C.; Lan C.-Y.; JING-JER LIN ; Lo L.-C.journal article44
222013Structure-based design, synthesis and biological evaluation of novel anthra[1,2-d]imidazole-6,11-dione homologues as potential antitumor agentsChen T.-C.; Yu D.-S.; Huang K.-F.; Fu Y.-C.; Lee C.-C.; Chen C.-L.; Huang F.-C.; Hsieh H.-H.; JING-JER LIN ; Huang H.-S.journal article1817
232012Synthesis, antiproliferative activities and telomerase inhibition evaluation of novel asymmetrical 1,2-disubstituted amidoanthraquinone derivativesLee C.-C.; Huang K.-F.; Lin P.-Y.; Huang F.-C.; Chen C.-L.; Chen T.-C.; Guh J.-H.; JING-JER LIN ; Huang H.-S.journal article2262
242012Synthesis, telomerase evaluation and anti-proliferative studies on various series of diaminoanthraquinone-lkinked aminoacyl residue derivativesHuang F.-C.; Huang K.-F.; Chen R.-H.; Wu J.-E.; Chen T.-C.; Chen C.-L.; Lee C.-C.; Chen J.-Y.; JING-JER LIN ; Huang H.-S.journal article77
252012Development of a plate-based assay platform to monitor cellular SHP2 phosphatase activity during erythroid differentiationChu C.-Y.; Kuo C.-C.; Chen M.-H.; Chen K.-J.; Lo L.-C.; JING-JER LIN journal article22
262012Depleting components of the THO complex causes increased telomere length by reducing the expression of the telomere-associated protein Rif1pYu T.-Y.; Wang C.-Y.; JING-JER LIN journal article32
272012Induction of senescence in cancer cells by the G-quadruplex stabilizer, BMVC4, is independent of its telomerase inhibitory activityHuang F.-C.; Chang C.-C.; Wang J.-M.; Chang T.-C.; JING-JER LIN journal article3030
282012C-Jun N-terminal kinase 1 negatively regulates osteoblastic differentiation induced by BMP2 via phosphorylation of Runx2 at Ser104Huang Y.-F.; JING-JER LIN ; Lin C.-H.; Su Y.; Hung S.-C.journal article4445
292012Design, synthesis and evaluation of telomerase inhibitory, hTERT repressing, and anti-proliferation activities of symmetrical 1,8-disubstituted amidoanthraquinonesLee C.-C.; Huang K.-F.; Chang D.-M.; Hsu J.-J.; Huang F.-C.; Shih K.-N.; Chen C.-L.; Chen T.-C.; Chen R.-H.; JING-JER LIN ; Huang H.-S.journal article1616
302011Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase αSun J.; Yang Y.; Wan K.; Mao N.; Yu T.-Y.; Lin Y.-C.; Dezwaan D.C.; Freeman B.C.; JING-JER LIN ; Lue N.F.; Lei M.journal article5149
312011Association of pituitary tumor transforming gene expression with early oral tumorigenesis and malignant progression of precancerous lesionsLiao L.-J.; Hsu Y.-H.; Yu C.-H.; Chiang C.-P.; Jhan J.-R.; Chang L.-C.; JING-JER LIN ; Lou P.-J.journal article88
322010NSC746364, NSC746365, and NSC746366: The spectra of cytotoxicity and molecular correlates of response to telomerase activityHuang H.-S.; Huang K.-F.; Lee C.-C.; Chen C.-L.; Li C.-L.; JING-JER LIN journal article88
3320105,10,15,20-Tetra-(N-methyl-3-pyridyl)porphyrin destabilizes the antiparallel telomeric quadruplex d(TTAGGG)4Dutikova Y.V.; Borisova O.F.; Shchyolkina A.K.; JING-JER LIN ; Huang S.; Shtil A.A.; Kaluzhny D.N.journal article1010
342010Development of activity-based probes with tunable specificity for protein tyrosine phosphatase subfamiliesHuang Y.-Y.; Kuo C.-C.; Chu C.-Y.; Huang Y.-H.; Hu Y.-L.; JING-JER LIN ; Lo L.-C.journal article109
352010Overexpression of the pituitary tumor transforming gene induces p53-dependent senescence through activating DNA damage response pathway in normal human fibroblastsHsu Y.-H.; Liao L.-J.; Yu C.-H.; Chiang C.-P.; Jhan J.-R.; Chang L.-C.; Chen Y.-J.; Lou P.-J.; JING-JER LIN journal article1820
362010Selective activation of SHP2 activity by cisplatin revealed by a novel chemical probe-based assayKuo C.-C.; Chu C.-Y.; JING-JER LIN ; Lo L.-C.journal article89
372009Sequential loading of Saccharomyces cerevisiae Ku and Cdc13p to telomeresWu T.-J.; Chiang Y.-H.; Lin Y.-C.; Tsai C.-R.; Yu T.-Y.; Sung M.-T.; Lee Y.-H.W.; JING-JER LIN journal article77
382009Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1,2-heteroannelated anthraquinones and anthra[ 1,2-d]imidazole-6,11 -dione homologuesHuang H.-S.; Chen T.-C.; Chen R.-H.; Huang K.-F.; Huang F.-C.; Jhan J.-R.; Chen C.-L.; Lee C.-C.; Lo Y.; JING-JER LIN journal article4645
392009Ten1p promotes the telomeric DNA-binding activity of Cdc13p: Implication for its function in telomere length regulationQian W.; Wang J.; Jin N.-N.; Fu X.-H.; Lin Y.-C.; JING-JER LIN ; Zhou J.-Q.journal article1314
402009Synthesis and cytotoxic properties of 4,11-bis[(aminoethyl)amino]anthra[2,3-b]thiophene-5,10-diones, novel analogues of antitumor anthracene-9,10-dionesShchekotikhin A.E.; Glazunova V.A.; Dezhenkova L.G.; Luzikov Y.N.; Sinkevich Y.B.; Kovalenko L.V.; Buyanov V.N.; Balzarini J.; Huang F.-C.; JING-JER LIN ; Huang H.-S.; Shtil A.A.; Preobrazhenskaya M.N.journal article3532
412008G-quadruplex stabilizer 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide induces accelerated senescence and inhibits tumorigenic properties in cancer cellsHuang F.-C.; Chang C.-C.; Lou P.-J.; Kuo I.-C.; Chien C.-W.; Chen C.-T.; Shieh F.-Y.; Chang T.-C.; JING-JER LIN journal article4644
422008Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivativesHuang H.-S.; Huang K.-F.; Li C.-L.; Huang Y.-Y.; Chiang Y.-H.; Huang F.-C.; JING-JER LIN journal article4036
432007Establishing cell-based reporter systems for the analysis of hTERT expression.Huang Y.Y.; Shih J.W.; JING-JER LIN journal article1
442007A concise paradigm for the construction of amide linker of 2,7-diamidoanthraquinone derivatives as potential telomerase inhibitorsHuang H.-S.; JING-JER LIN ; Huang K.-F.; Li C.-L.journal article2
452007Genetic analysis reveals essential and non-essential amino acids within the telomeric DNA-binding interface of Cdc13pLin Y.-C.; Wu Lee Y.-H.; JING-JER LIN journal article23
462007Synthesis and human telomerase inhibition of a series of regioisomeric disubstituted amidoanthraquinonesHuang H.-S.; Chen I.-B.; Huang K.-F.; Lu W.-C.; Shieh F.-Y.; Huang Y.-Y.; Huang F.-C.; JING-JER LIN journal article3333
472007The U3 small nucleolar ribonucleoprotein component Imp4p is a telomeric DNA-binding proteinHsieh Y.-C.; Tu P.-J.; Lee Y.-Y.; Kuo C.-C.; Lin Y.-C.; Wu C.-F.; JING-JER LIN journal article44
482006Rapid and selective isolation of β-xylosidase through an activitybased chemical approachLo L.-C.; Chu C.-Y.; Pan Y.-R.; Wan C.-F.; Li Y.-K.; JING-JER LIN journal article50
492006Synthesis of activity probes for β-xylosidaseLo L.-C.; Chu C.-Y.; Lin F.-A.; Pan Y.-R.; Li Y.-K.; JING-JER LIN journal article32
502006The tea polyphenols EGCG and EGC repress mRNA expression of human telomerase reverse transcriptase (hTERT) in carcinoma cellsLin S.-C.; Li W.-C.; Shih J.-W.; Hong K.-F.; Pan Y.-R.; JING-JER LIN journal article3734
512006The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylationTseng S.-F.; JING-JER LIN ; Teng S.-C.journal article8989
522006Facile synthesis toward the construction of an activity probe library for glycosidasesShie T.-H.; Chiang Y.-L.; JING-JER LIN ; Li Y.-K.; Lo L.-C.journal article43
532005Telomere and telomerase as targets for anti-cancer and regeneration therapiesHsu Y.-H.; JING-JER LIN Review2017
542005Human telomerase inhibition and cytotoxicity of regioisomeric disubstituted amidoanthraquinones and aminoanthraquinonesHuang H.-S.; Chou C.-L.; Guo C.-L.; Yuan C.-L.; Lu Y.-C.; Shieh F.-Y.; JING-JER LIN journal article3229
552004Nuclear βII-tubulin associates with the activated notch receptor to modulate notch signalingYeh T.-S.; Hsieh R.-H.; Shen S.-C.; Wang S.-H.; Tseng M.-J.; Shih C.-M.; JING-JER LIN journal article1918
562004A novel carbazole derivative, BMVC: A potential antitumor agent and fluorescence marker of cancer cellsChang C.-C.; Kuo I.-C.; JING-JER LIN ; Lu Y.-C.; Chenc C.-T.; Back H.-T.; Lou P.-J.; Chang T.-C.journal article6567
572004Detection of quadruplex DNA structures in human telomeres by a fluorescent carbazole derivativeChang C.-C.; Kuo I.-C.; Ling I.-F.; Chen C.-T.; Chen H.-C.; Lou P.-J.; JING-JER LIN ; Chang T.-C.journal article147142
582004Study of the preferred modification sites of the quinone methide intermediate resulting from the latent trapping device of the activity probes for hydrolasesLo L.-C.; Chiang Y.-L.; Kuo C.-H.; Liao H.-K.; Chen Y.-J.; JING-JER LIN journal article2523
592004Chromosome positional effects of gene expressions after cellular senescenceChen H.-L.; Lu C.-Y.; Hsu Y.-H.; JING-JER LIN journal article87
602004Interaction of Saccharomyces Cdc13p with Pol1p, Imp4p, Sir4p and Zds2p is involved in telomere replication, telomere maintenance and cell growth controlHsu C.-L.; Chen Y.-S.; Tsai S.-Y.; Tu P.-J.; Wang M.-J.; JING-JER LIN journal article2424
612003Exposure of single-stranded telomeric DNA causes G2/M cell cycle arrest in Saccharomyces cerevisiaePang T.-L.; Wang C.-Y.; Hsu C.-L.; Chen M.-Y.; JING-JER LIN journal article1615
622003Crystallization and preliminary crystallographic analysis of yeast cytosine deaminaseHsu Y.-H.; Hu C.-Y.; JING-JER LIN ; Liaw S.-H.journal article22
632003Activation of human telomerase reverse transcriptase expression by some new symmetrical bis-substituted derivatives of the anthraquinoneHuang H.-S.; Chiou J.-F.; Fong Y.; Hou C.-C.; Lu Y.-C.; Wang J.-Y.; Shih J.-W.; Pan Y.-R.; JING-JER LIN journal article5648
642003Crystal structure of yeast cytosine deaminase: Insights into enzyme mechanism and evolutionKo T.-P.; JING-JER LIN ; Hu C.-Y.; Hsu Y.-H.; Wang A.H.-J.; Liaw S.-H.journal article9092
652002Induction of global stress response in Saccharomyces cerevisiae cells lacking telomeraseTeng S.-C.; Tsai Y.-L.; Cheng H.-W.; Epstein C.; Chen H.-L.; JING-JER LIN journal article1112
662002Investigation of DNA-protein recognition by satellite hole spectra of labeling dyeChang T.-C.; JING-JER LIN ; Lin K.-C.; Lin Y.-C.; Huang W.-C.; Yang Y.-P.; Cheng J.-Y.conference paper23
672002Design and synthesis of class-selective activity probes for protein tyrosine phosphatasesLo L.-C.; Pang T.-L.; Kuo C.-H.; Chiang Y.-L.; Wang H.-Y.; JING-JER LIN journal article9997
682001Renaturation and stabilization of the telomere-binding activity of Saccharomyces Cdc13(451-693)p by L-arginineLin Y.-C.; Shih J.-W.; Hsu C.-L.; JING-JER LIN journal article63
692001Binding and Partial Denaturing of G-quartet DNA by Cdc13p of Saccharomyces cerevisiaeLin Y.-C.; Shih J.-W.; Hsu C.-L.; JING-JER LIN journal article2831
702001Studies on anthracenes. 1. Human telomerase inhibition and lipid peroxidation of 9-acyloxy 1,5-dichloroanthracene derivativesHuang H.-S.; Hwang J.-M.; Jen Y.-M.; JING-JER LIN ; Lee K.-Y.; Shi C.-H.; Hsu H.-C.journal article2521
712001Specific Binding of Single-stranded Telomeric DNA by Cdc13p of Saccharomyces cerevisiaeLin Y.-C.; Hsu C.-L.; Shih J.-W.; JING-JER LIN journal article1717
722000Telomere-binding and Stn1p-interacting activities are required for the essential function of Saccharomyces cerevisiae Cdc13pWang M.-J.; Lin Y.-C.; Pang T.-L.; Lee J.-M.; Chou C.-C.; JING-JER LIN journal article24
731996The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivoJING-JER LIN ; Zakian V.A.journal article255263
741995An in vitro assay for saccharomyces telomerase requires EST1JING-JER LIN ; Zakian V.A.journal article10296
751994Isolation and characterization of two Saccharomyces cerevisiae genes that encode proteins that bind to (TG1-3)n single strand telomeric DNA in vitroJING-JER LIN ; Zakian V.A.journal article4649
761994Corrigendum: Isolation and characterization of two Saccharomyces cerevisiae genes that encode protein that bind to (TG1-3)(n) single strand telomeric DNA in vitro (Nucleic Acids Research, 1994, 22, 4906-4913))JING-JER LIN ; Zakian V.A.erratum0
771993What the papers say: Telomeric DNA binding proteinsJING-JER LIN journal article44
781992Active site of (A)BC excinuclease. I. Evidence for 5' incision by UvrC through a catalytic site involving Asp399, Asp438, Asp466, and His538 residuesJING-JER LIN ; Sancar A.journal article103
791992Active site of (A)BC excinuclease. II. Binding, bending, and catalysis mutants of UvrB reveal a direct role in 3' and an indirect role in 5' incisionJING-JER LIN ; Phillips A.M.; Hearst J.E.; Sancar A.journal article92
801992(A)BC excinuclease: the Escherichia coli nucleotide excision repair enzymeJING-JER LIN ; Sancar A.Review8891
811991The C-terminal half of UvrC protein is sufficient to reconstitute (A)BC excinucleaseJING-JER LIN ; Sancar A.journal article1619
821990Reconstitution of nucleotide excision nuclease with UvrA and UvrB proteins from Escherichia coli and UvrC protein from Bacillus subtilisJING-JER LIN ; Sancar A.journal article25
831989A New Mechanism for Repairing Oxidative Damage to DNA: (A)BC Excinuclease Removes AP Sites and Thymine Glycols from DNAJING-JER LIN ; Sancar A.journal article150170
841988A trans-acting gene is required for the phenotypic expression of a tyrosinase gene in StreptomycesLee Y.-H.W.; Chen B.-F.; Wu S.-Y.; Leu W.-M.; JING-JER LIN ; Chen C.W.; Lo S.J.journal article3748