第 1 到 42 筆結果,共 42 筆。
公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 | |
---|---|---|---|---|---|---|---|
1 | 2024 | Discovery of new dibenzodiazepine derivatives as antibacterials against intracellular bacteria | Chen, Ling-Han; Lin, Man-Yi; Lin, Hsueh-Chun; Yang, Fan-Wei; Liao, Hsiao-Wei; Shiau, Chung-Wai; HAO-CHIEH CHIU ; Su, Jung-Chen | RSC medicinal chemistry | |||
2 | 2023 | Performance assessment of the Bruker Biotyper MALDI-TOF MS for the identification of difficult-to-identify viridans group streptococci | Wan, Tsai-Wen; Lee, Tai-Fen; Chen, Xiang-Jun; Hunag, Yun-Tsung; LEE-JENE TENG ; PO-REN HSUEH ; HAO-CHIEH CHIU | Journal of clinical microbiology | |||
3 | 2023 | Repurposing the tyrosine kinase inhibitor nilotinib for use against intracellular multidrug-resistant Salmonella Typhimurium | Chou, Shih-Hsiu; Wan, Tsai-Wen; Shiau, Chung-Wai; Chen, Ling-Han; Lin, Hsueh-Chun; HAO-CHIEH CHIU | Journal of microbiology, immunology, and infection | 0 | 0 | |
4 | 2022 | Rapid Bactericidal Activity of SC5005 Combined with Docosahexaenoic Acid against Multidrug-Resistant Staphylococcus aureus Persisters and Biofilms | Yeo, Hui-Hui; Shiau, Chung-Wei; Jao, Yu-Hsuan; Wan, Tsai-Wen; HAO-CHIEH CHIU | Antimicrobial agents and chemotherapy | 0 | 0 | |
5 | 2022 | Molecular epidemiology of bacteraemic vancomycin-resistant Enterococcus faecium isolates and in vitro activities of SC5005 and other comparators against these isolates collected from a medical centre in northern Taiwan, 2019-2020 | Wan, Tsai-Wen; Yeo, Hui-Hui; Lee, Tai-Fen; YU-TSUNG HUANG ; PO-REN HSUEH ; HAO-CHIEH CHIU | The Journal of antimicrobial chemotherapy | 2 | 2 | |
6 | 2022 | Discovery of antipsychotic loxapine derivatives against intracellular multidrug-resistant bacteria | Lin, Hsueh-Chun; Wu, Yi-Lun; Hsu, Cheng-Yun; Lin, Man-Yi; Chen, Ling-Han; Shiau, Chung-Wai; HAO-CHIEH CHIU | RSC Medicinal Chemistry | 2 | ||
7 | 2021 | Unique virulence role of post-translocational chaperone PrsA in shaping Streptococcus pyogenes secretome | Wu, Zhao-Yi; Campeau, Anaamika; Liu, Chao-Hsien; Gonzalez, David J; Yamaguchi, Masaya; Kawabata, Shigetada; Lu, Chieh-Hsien; Lai, Chian-Yu; HAO-CHIEH CHIU ; YUNG-CHI CHANG | Virulence | 4 | 3 | |
8 | 2021 | SC5005 dissipates the membrane potential to kill Staphylococcus aureus persisters without detectable resistance | Lu, Chieh-Hsien; Shiau, Chung-Wai; YUNG-CHI CHANG ; HSIU-NI KUNG ; JUI-CHING WU ; Lim, Chui-Hian; Yeo, Hui-Hui; Chang, Han-Chu; Chien, Han-Sheng; Huang, Sheng-Hsuan; Hung, Wei-Kang; Wei, Jun-Rong; HAO-CHIEH CHIU | The Journal of antimicrobial chemotherapy | 8 | 8 | |
9 | 2021 | Potentially conjugative plasmids harboring Tn6636, a multidrug-resistant and composite mobile element, in Staphylococcus aureus | Wan, Tsai-Wen; Liu, Yu-Jung; YUN-TUNG WANG ; Lin, Yu-Tzu; Hsu, Jia-Chuan; JUI-CHANG TSAI ; HAO-CHIEH CHIU ; PO-REN HSUEH ; Hung, Wei-Chun; LEE-JENE TENG | Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi | 5 | 5 | |
10 | 2021 | A Novel Dibenzoxazepine Attenuates Intracellular Salmonella Typhimurium Oxidative Stress Resistance | Hsu, Cheng-Yun; Wu, Yi-Lun; Lin, Hsueh-Chun; Lin, Man-Yi; Chou, Shih-Hsiu; Shiau, Chung-Wai; HAO-CHIEH CHIU | Microbiology spectrum | 2 | 2 | |
11 | 2020 | A celecoxib derivative eradicates antibiotic-resistant staphylococcus aureus and biofilms by targeting yidc2 translocase | SHIOU-RU TZENG ; Huang Y.-W.; Zhang Y.-Q.; Yang C.-Y.; Chien H.-S.; Chen Y.-R.; SUNG-LIANG YU ; Chen C.S.; HAO-CHIEH CHIU | International Journal of Molecular Sciences | 5 | 5 | |
12 | 2019 | Loxapine, an antipsychotic drug, suppresses intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages | Yang C.-Y.; Hsu C.-Y.; Fang C.-S.; Shiau C.-W.; Chen C.S.; HAO-CHIEH CHIU | Journal of Microbiology, Immunology and Infection | 11 | 10 | |
13 | 2018 | A multi-omic analysis reveals the role of fumarate in regulating the virulence of enterohemorrhagic Escherichia coli | Kuo, C.-J.; Wang, S.-T.; Lin, C.-M.; HAO-CHIEH CHIU ; Huang, C.-R.; Lee, D.-Y.; Chang, G.-D.; Chou, T.-C.; Chen, J.-W.; GEEN-DONG CHANG | Cell Death and Disease | 19 | 17 | |
14 | 2018 | Design and synthesis of malonamide derivatives as antibiotics against methicillin-resistant staphylococcus aureus | Su, J.-C.; Huang, Y.-T.; Chen, C.-S.; HAO-CHIEH CHIU ; Shiau, C.-W. | Molecules | 8 | 9 | |
15 | 2017 | Rapid Sputum Multiplex Detection of the M. tuberculosis Complex (MTBC) and Resistance Mutations for Eight Antibiotics by Nucleotide MALDI-TOF MS | KANG-YI SU ; BO-SHIUN YAN ; HAO-CHIEH CHIU ; CHONG-JEN YU ; Chang S.-Y.; Jou R.; Liu J.-L.; PO-REN HSUEH ; SUNG-LIANG YU | Scientific Reports | 16 | 10 | |
16 | 2017 | Effects of toluidine blue O (TBO)-photodynamic inactivation on community-associated methicillin-resistant Staphylococcus aureus isolates | Tseng S.-P.; Hung W.-C.; Chen H.-J.; Lin Y.-T.; Jiang H.-S.; HAO-CHIEH CHIU ; PO-REN HSUEH ; LEE-JENE TENG ; JUI-CHANG TSAI | Journal of Microbiology, Immunology and Infection | 25 | 21 | |
17 | 2016 | Substituted malonamides and their use as antibacterial drugs | HAO-CHIEH CHIU ; Chung-Wai Shiau | US patent: US10800732 | |||
18 | 2016 | Substituted malonamides and their use as antibacterial drugs | HAO-CHIEH CHIU ; Chung-Wai Shiau | EU patent: EP3331852 | |||
19 | 2016 | Mutation of the enterohemorrhagic escherichia coli core LPS biosynthesis enzyme RfaD confers hypersusceptibility to host intestinal innate immunity in vivo | Kuo C.-J.; Chen J.-W.; HAO-CHIEH CHIU ; Teng C.-H.; Hsu T.-I.; Lu P.-J.; Syu W.-J.; Wang S.T.; Chou T.-C.; Chen C.-S. | Frontiers in Cellular and Infection Microbiology | 15 | 18 | |
20 | 2016 | Disrupting VEGF-A paracrine and autocrine loops by targeting SHP-1 suppresses triple negative breast cancer metastasis | Su J.-C.; Mar A.-C.; Wu S.-H.; Tai W.-T.; Chu P.-Y.; Wu C.-Y.; Tseng L.-M.; Lee T.-C.; Chen K.-F.; Liu C.-Y.; HAO-CHIEH CHIU ; Shiau C.-W. | Scientific Reports | 44 | 34 | |
21 | 2016 | In vitro and in vivo activity of a novel sorafenib derivative SC5005 against MRSA | Chang H.-C.; YU-TSUNG HUANG ; Chen C.-S.; Chen Y.-W.; Su J.-C.; LEE-JENE TENG ; Shiau C.-W.; HAO-CHIEH CHIU | Journal of Antimicrobial Chemotherapy | 24 | 22 | |
22 | 2016 | Substituted malonamides and their use as antibacterial drugs | HAO-CHIEH CHIU ; Chung-Wai Shiau | 中國專利: CN108026027 | |||
23 | 2016 | 經取代的丙二醯胺化合物及其作爲抗菌藥物的用途 | HAO-CHIEH CHIU ; Chung-Wai Shiau | 中華民國專利: I675817 | |||
24 | 2015 | A novel fusidic acid resistance determinant, fusF, in Staphylococcus cohnii | Chen H.-J.; Hung W.-C.; Lin Y.-T.; JUI-CHANG TSAI ; HAO-CHIEH CHIU ; PO-REN HSUEH ; LEE-JENE TENG | Journal of Antimicrobial Chemotherapy | 20 | 20 | |
25 | 2014 | Sensitization of intracellular Salmonella enterica serovar Typhimurium to aminoglycosides in vitro and in vivo by a host-targeted antimicrobial agent | Lo, Jung-Hsin; Kulp, Samuel K; Chen, Ching-Shih; HAO-CHIEH CHIU | Antimicrobial agents and chemotherapy | 22 | 21 | |
26 | 2014 | Compositions and methods for sensitizing intracellular bacteria to aminoglycosides | HAO-CHIEH CHIU ; Samuel K. Kulp; Ching-Shih Chen | US provisional patent: 61/993819 | |||
27 | 2013 | Histone deacetylase inhibitor AR42 regulates telomerase activity in human glioma cells via an Akt-dependent mechanism | Yang, Y.-L.; Huang, P.-H.; HAO-CHIEH CHIU ; Kulp, S.K.; Chen, C.-S.; Kuo, C.-J.; Chen, H.-D.; Chen, C.-S. | Biochemical and Biophysical Research Communications | 18 | 16 | |
28 | 2013 | Vitamin e facilitates the inactivation of the kinase akt by the phosphatase PHLPP1 | Huang, P.-H.; Chuang, H.-C.; Chou, C.-C.; Wang, H.; Lee, S.-L.; Yang, H.-C.; HAO-CHIEH CHIU ; Kapuriya, N.; Wang, D.; Kulp, S.K.; Chen, C.-S. | Science Signaling | 45 | 43 | |
29 | 2013 | Enterohaemorrhagic Escherichia coli O157: H7 Shiga-like toxin 1 is required for full pathogenicity and activation of the p38 mitogen-activated protein kinase pathway in Caenorhabditis elegans | Chou, T.-C.; HAO-CHIEH CHIU ; Kuo, C.-J.; Wu, C.-M.; Syu, W.-J.; Chiu, W.-T.; Chen, C.-S. | Cellular Microbiology | 48 | 48 | |
30 | 2012 | Escherichia coli O104:H4 | Hsiao-Jan Chen; HAO-CHIEH CHIU ; Lee-Jene Teng | Formosa Journal of Medicine | 0 | ||
31 | 2012 | Tularemia, A Potential Bioterrorism Threat | HAO-CHIEH CHIU ; Bo-Shiun Yan | Formosa Journal of Medicine | 0 | ||
32 | 2012 | Anti-Francisella agents | HAO-CHIEH CHIU ; Ching-Shih Chen; Samuel Kulp; John S. Gunn; Larry S. Schlesinger | US patent: US8580827 | |||
33 | 2012 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus | HAO-CHIEH CHIU ; Lee S.-L.; Kapuriya N.; Wang D.; Chen Y.-R.; SUNG-LIANG YU ; Kulp S.K.; LEE-JENE TENG ; Chen C.-S. | Bioorganic and Medicinal Chemistry | 35 | 29 | |
34 | 2010 | Pyrazole derivatives as anti-Francisella agents | HAO-CHIEH CHIU ; Ching-Shih Chen; Samuel Kulp; John S. Gunn; Larry S. Schlesinger | EU patent: EP2246332 | |||
35 | 2009 | Eradication of intracellular Salmonella enterica serovar typhimurium with a small-molecule, host cell-directed agent | HAO-CHIEH CHIU ; Kulp, S.K.; Soni, S.; Wang, D.; Gunn, J.S.; Schlesinger, L.S.; Chen, C.-S. | Antimicrobial Agents and Chemotherapy | 66 | 68 | |
36 | 2009 | Eradication of intracellular Francisella tularensis in THP-1 human macrophages with a novel autophagy inducing agent | HAO-CHIEH CHIU ; Soni, S.; Kulp, S.K.; Curry, H.; Wang, D.; Gunn, J.S.; Schlesinger, L.S.; Chen, C.S. | Journal of biomedical science | 58 | 58 | |
37 | 2009 | Pharmacological exploitation of an off-target antibacterial effect of the cyclooxygenase-2 inhibitor celecoxib against Francisella tularensis | HAO-CHIEH CHIU ; Yang, J.; Soni, S.; Kulp, S.K.; Gunn, J.S.; Schlesinger, L.S.; Chen, C.-S. | Antimicrobial Agents and Chemotherapy | 19 | 19 | |
38 | 2008 | Anti-infective agents against intracellular pathogens | HAO-CHIEH CHIU ; Ching-Shih Chen; Dasheng Wang; John S. Gunn; Larry S. Schlesinger | US patent: US8039502 | |||
39 | 2006 | Comparison of Tir from enterohemorrahgic and enteropathogenic Escherichia coli strains: Two homologues with distinct intracellular properties | Chuang C.-H.; HAO-CHIEH CHIU ; Hsu S.-C.; Ho J.-Y.; Syu W.-J. | Journal of Biomedical Science | 4 | 4 | |
40 | 2006 | Development of small-molecule cyclin D1-ablative agents | Huang J.-W.; Shiau C.-W.; Yang J.; Wang D.-S.; HAO-CHIEH CHIU ; Chen C.-Y.; Chen C.-S. | Journal of Medicinal Chemistry | 52 | 48 | |
41 | 2005 | Functional analysis of EspB from enterohaemorrhagic Escherichia coli | HAO-CHIEH CHIU ; Syu W.-J. | Microbiology | 14 | 15 | |
42 | 2003 | Type III secretion of EspB in enterohemorrhagic Escherichia coli O157:H7 | HAO-CHIEH CHIU ; Lin W.-S.; Syu W.-J. | Archives of Microbiology | 17 | 17 |