Publications

Results 1-120 of 120 (Search time: 0.015 seconds).

Issue DateTitleAuthor(s)TypescopusWOSFulltext/Archive link
12018Design, synthesis and cytotoxic activity of N-Modified oleanolic saponins bearing A glucosamineJIH-HWA GUH ; PI-HUI LIANG journal article
22018Discovery of aliphatic-chain hydroxamates containing indole derivatives with potent class I histone deacetylase inhibitory activitiesJIH-HWA GUH journal article
32018An integrated approach to elucidate signaling pathways of dioscin-induced apoptosis, energy metabolism and differentiation in acute myeloid leukemiaJIH-HWA GUH ; PI-HUI LIANG journal article
42017Enantiomerically pure �]-dipeptide derivative induces anticancer activity against human hormone-refractory prostate cancer through both PI3K/Akt-dependent and -independent pathwaysJIH-HWA GUH ; SHIH-PING LIU journal article
52016ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5JIH-HWA GUH journal article
62016Hemiasterlin derivative (R)(S)(S)-BF65 and Akt inhibitor MK-2206 synergistically inhibit SKOV3 ovarian cancer cell growthJIH-HWA GUH journal article
72016Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: The role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathwaysJIH-HWA GUH ; Leu, Wohn-Jenn; SHIH-PING LIU ; Swain, Sharada Prasanna; Chan, She-Hung; Hsu, Jui-Ling; Liu, Shih-Ping ; Chan, Mei-Ling; Yu, Chia-Chun; Hsu, Lih-Ching ; Chou, Yen-Lin; Chang, Wei-Ling; Hou, Duen-Ren; Guh, Jih-Hwa journal article
82016Synthesis and characterization of ruthenium compounds incorporating keto-amine ligands. The applications of catalytic transfer hydrogenation and cancer cell inhibitionJIH-HWA GUH journal article
92016臺灣六年制藥學教育的創建JIH-HWA GUH ; YUNN-FANG HO journal article
102015Design, synthesis and biological evaluation of tetracyclic azafluorenone derivatives with topoisomerase I inhibitory properties as potential anticancer agentsJIH-HWA GUH ; JING-JER LINjournal article
112015Epi-reevesioside F inhibits Na+/K+-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastomaJIH-HWA GUH ; FAN-LU KUNG journal article
122015Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between endoplasmic reticulum stress and mitochondrial insultJIH-HWA GUH ; SHOEI-SHENG LEE journal article
132015Structural studies and anticancer activity of a novel class of β-peptidesJIH-HWA GUH journal article
142015Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells - A critical role of Cdk1 in mitotic entryJIH-HWA GUH journal article
152015Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer - A crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activationJIH-HWA GUH journal article
162015Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathwayHo, Chen-Hsun; JIH-HWA GUH ; Hsu, Jui-Ling; Hsu, Jui-Ling; SHIH-PING LIU ; Liu, Shih-Ping ; Liu, Shih-Ping ; Hsu, Lih-Ching ; Hsu, Lih-Ching ; Chang, Wei-Ling; Chao, Chuck C. -K.; Chao, Chuck C. -K.; Guh, Jih-Hwa ; Guh, Jih-Hwa journal article
172015Catalytic transfer hydrogenation and anticancer activity of arene-ruthenium compounds incorporating bi-dentate precursorsJIH-HWA GUH journal article
182015Ring fusion strategy for synthesis and lead optimization of sulfur-substituted anthra[1,2-c[[1,2,5]thiadiazole-6,11-dione derivatives as promising scaffold of antitumor agentsJIH-HWA GUH journal article
192015Cytotoxic protobassic acid glycosides from Planchonella obovata leafJIH-HWA GUH ; SHOEI-SHENG LEE journal article
202015KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora a activityJIH-HWA GUH ; Yu, Chia-Chun; Liu, Shih-Ping ; SHIH-PING LIU ; Hsu, Jui-Ling; Hsu, John T. A.; Kudryavtsev, Konstantin V.; Guh, Jih-Hwa journal article
212015Menthols as Chiral Auxiliaries for Asymmetric Cycloadditive Oligomerization: Syntheses and Studies of β-Proline HexamersJIH-HWA GUH journal article
222014Reevesioside A, a Cardenolide Glycoside, Induces Anticancer Activity against Human Hormone-Refractory Prostate Cancers through Suppression of c-myc Expression and Induction of G1 Arrest of the Cell Cycle.JIH-HWA GUH dissertation
232014A unique amidoanthraquinone derivative displays antiproliferative activity against human hormone-refractory metastatic prostate cancers through activation of LKB1-AMPK-mTOR signaling pathwayHsu, Jui-Ling; JIH-HWA GUH ; Liu, Shih-Ping ; LIH-CHING HSU ; SHIH-PING LIU ; Lee, Chia-Chung; Hsu, Lih-Ching ; YUNN-FANG HO ; Ho, Yunn-Fang ; Huang, Hsu-Shan; Guh, Jih-Hwa journal article
242014Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruptionJIH-HWA GUH ; TZONG-HUEI LEEjournal article
252014Synthesis and anti-cancer activity of a glycosyl library of \\varvec{N} N -acetylglucosamine-bearing oleanolic acidJIH-HWA GUH ; PI-HUI LIANG journal article
262014Ring fusion strategy for the synthesis of anthra[2,3-d ]oxazole-2-thione-5,10-dione homologues as DNA topoisomerase inhibitors and as antitumor agentsJIH-HWA GUH journal article
272014A general synthetic strategy and the anti-proliferation properties on prostate cancer cell lines for natural phenylethanoid glycosidesJIH-HWA GUH journal article
282014Terfenadine induces anti-proliferative and apoptotic activities in human hormone-refractory prostate cancer through histamine receptor-independent Mcl-1 cleavage and Bak up-regulationJIH-HWA GUH ; Wang, Wei-Ting; Chen, Yen-Hui ; LIH-CHING HSU ; Hsu, Jui-Ling; YUNN-FANG HO ; Leu, Wohn-Jenn; Yu, Chia-Chun; Chan, She-Hung; Ho, Yunn-Fang ; Hsu, Lih-Ching ; Guh, Jih-Hwa journal article
292014The Akt inhibitor MK-2206 enhances the cytotoxicity of paclitaxel (Taxol) and cisplatin in ovarian cancer cellsWang, Ke-Deng; JIH-HWA GUH ; Lin, Ying-Hsi; Chen, Bert Yu-Hung; Chen, Pai-Shan ; LIH-CHING HSU ; Huang, Shang-Da; Lai, Wei-Ting; ANN-LII CHENG ; 陳珮珊 ; Wu, Shao-Fu; Guh, Jih-Hwa ; Cheng, Ann-Lii; Hsu, Lih-Ching journal article
302014Reevesioside A, a cardenolide glycoside, induces anticancer activity against human hormone-refractory prostate cancers through suppression of c-myc expression and induction of G1 arrest of the cell cycleJIH-HWA GUH ; LIH-CHING HSU journal article
312014A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase iYu, Chia-Chun; JIH-HWA GUH ; TSAI-KUN LI ; Pan, Shiow-Lin; Chao, Shi-Wei; SHIH-PING LIU ; Liu, Shih-Ping ; Hsu, Jui-Ling; Yang, Yu-Chen; Li, Tsia-Kun; Huang, Wei-Jan; Guh, Jih-Hwa journal article
322014Calanquinone A induces anti-glioblastoma activity through glutathione-involved DNA damage and AMPK activationJIH-HWA GUH ; FAN-LU KUNG journal article
332014Moniliformediquinone induces in vitro and in vivo antitumor activity through glutathione involved DNA damage response and mitochondrial stress in human hormone refractory prostate cancerJIH-HWA GUH journal article
342014Synthesis and biological evaluation of anthra[1,9-cd]pyrazol-6(2H)-one scaffold derivatives as potential anticancer agentsJIH-HWA GUH ; JING-JER LINjournal article
352013Structure-based design, synthesis and evaluation of novel anthra[1,2-d]imidazole-6,11-dione derivatives as telomerase inhibitors and potential for cancer polypharmacologyJIH-HWA GUH ; JING-JER LINjournal article
362013Reevesioside F induces potent and efficient anti-proliferative and apoptotic activities through Na+/K+-ATPase α3 subunit-involved mitochondrial stress and amplification of caspase cascadesJIH-HWA GUH ; LIH-CHING HSU journal article
372013Design, synthesis and antiproliferative evaluation of fluorenone analogs with DNA topoisomerase i inhibitory propertiesJIH-HWA GUH journal article
382013Total synthesis of 14,21-diepi-squamocin-KJIH-HWA GUH journal article
392013Synthesis of a chlorogenin glycoside library using an orthogonal protecting group strategyJIH-HWA GUH journal article
4020132-(1H-Imidazol-1-yl)-4-[3-(trifluoromethyl)phenyl]-1,3-thiazoleJIH-HWA GUH journal article
412013A novel hydroxysuberamide derivative potentiates MG132-mediated anticancer activity against human hormone refractory prostate cancers - The role of histone deacetylase and endoplasmic reticulum stressJIH-HWA GUH journal article
422013Ardisianone, a natural benzoquinone, efficiently induces apoptosis in human hormone-refractory prostate cancers through mitochondrial damage stress and survivin downregulationJIH-HWA GUH ; LIH-CHING HSU ; YUNN-FANG HO journal article
432013Erratum: Anti-angiogenic effects and mechanism of prazosin (The Prostate (2011) 71 (976-984))JIH-HWA GUH ; HONG-JENG YU journal article
442012Pycnidione, a fungus-derived agent, induces cell cycle arrest and apoptosis in A549 human lung cancer cellsJIH-HWA GUH ; TZONG-HUEI LEEjournal article
452012Synthesis, antiproliferative activities and telomerase inhibition evaluation of novel asymmetrical 1,2-disubstituted amidoanthraquinone derivativesJIH-HWA GUH ; JING-JER LINjournal article
462012Antroquinonol, a natural ubiquinone derivative, induces a cross talk between apoptosis, autophagy and senescence in human pancreatic carcinoma cellsJIH-HWA GUH journal article
472012Bioactive diterpenes from Callicarpa longissimaJIH-HWA GUH journal article
482012Pim-1 knockdown potentiates paclitaxel-induced apoptosis in human hormone-refractory prostate cancers through inhibition of NHEJ DNA repairJIH-HWA GUH ; LIH-CHING HSU ; YUNN-FANG HO journal article
492012Chemical modification and anticancer effect of prenylated flavanones from Taiwanese propolisJIH-HWA GUH ; SHOEI-SHENG LEE journal article
502012Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathwayJIH-HWA GUH ; TSAI-KUN LI ; LIH-CHING HSU ; YUNN-FANG HO journal article
512011ICAM-1 and AMPK regulate cell detachment and apoptosis by N-methyl-N'-nitro-N-nitrosoguanidine, a widely spread environmental chemical, in human hormone-refractory prostate cancersJIH-HWA GUH journal article
522011Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitorsJIH-HWA GUH journal article
532011Anti-angiogenic effects and mechanism of prazosinJIH-HWA GUH ; HONG-JENG YU journal article
542011Targeting energy metabolic and oncogenic signaling pathways in triple-negative breast cancer by a novel adenosine monophosphate-activated protein kinase (AMPK) activatorJIH-HWA GUH journal article
552011Paclitaxel induces apoptosis through activation of nuclear protein kinase C-δ and subsequent activation of Golgi associated Cdk1 in human hormone refractory prostate cancerJIH-HWA GUH ; FAN-LU KUNG ; YUNN-FANG HO journal article
562011A unique P-glycoprotein interacting agent displays anticancer activity against hepatocellular carcinoma through inhibition of GRP78 and mTOR pathwaysJIH-HWA GUH journal article
572011Total synthesis of moniliformediquinone and calanquinone A as potent inhibitors for breast cancerJIH-HWA GUH ; CHE-MING TENG journal article
582011Costunolide induces apoptosis through nuclear calcium2+ overload and DNA damage response in human prostate cancerJIH-HWA GUH ; FAN-LU KUNG ; YUNN-FANG HO journal article
592011WJ9708012 exerts anticancer activity through PKC-α related crosstalk of mitochondrial and endoplasmic reticulum stresses in human hormone-refractory prostate cancer cellsJIH-HWA GUH journal article
602010Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: A crucial role of AMPK and mTOR pathwaysCHING-HUA KUO ; JIH-HWA GUH journal article
612010Methoxychalcone induces cell-cycle arrest and apoptosis in human hormone-resistant prostate cancer cells through PI 3-kinase-independent inhibition of mTOR pathwaysJIH-HWA GUH journal article
622010Anticancer activity of a cyclooxygenase inhibitor, CX9051, in human prostate cancer cells: The roles of NF-κB and crosstalk between the extrinsic and intrinsic apoptotic pathwaysJIH-HWA GUH ; Huang, Chiung-Hua; Guh, Jih-Hwa ; Chen, Grace Shiahuy; Lu, Pin-Hsuan; Chern, Ji-Wang journal article
632010Cryptocaryone, a Natural Dihydrochalcone, Induces Apoptosis in Human Androgen Independent Prostate Cancer Cells by Death Receptor Clustering in Lipid Raft and Nonraft CompartmentsJIH-HWA GUH ; FAN-LU KUNG journal article
642010The indazole derivative YD-3 specifically inhibits thrombin-induced angiogenesis in vitro and in vivoJIH-HWA GUH ; CHE-MING TENG journal article
6520102-Phenyl-5-(pyrrolidin-1-yl)-1-(3,4,5-trimethoxybenzyl)-1H-benzimidazole, a benzimidazole derivative, inhibits growth of human prostate cancer cells by affecting tubulin and c-Jun N-terminal kinaseJIH-HWA GUH ; YUNN-FANG HO journal article
662009Tunicamycin induces resistance to camptothecin and etoposide in human hepatocellular carcinoma cells: Role of cell-cycle arrest and GRP78JIH-HWA GUH journal article
672009abeo-taxane diterpenoids from the Taiwanese yew Taxus sumatranaJIH-HWA GUH journal article
682008Elucidation of susceptible factors to endoplasmic reticulum stress-mediated anticancer activity in human hepatocellular carcinomaJIH-HWA GUH journal article
692008New bioactive clerodane diterpenoids from the roots of Casearia membranaceaJIH-HWA GUH journal article
702008Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stressJIH-HWA GUH ; YUNN-FANG HO journal article
712008WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancersLING-WEI HSIN ; JIH-HWA GUH ; TSAI-KUN LI journal article
722008Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugatesLING-WEI HSIN ; JIH-HWA GUH ; TSAI-KUN LI journal article
732008The p38 mitogen-activated protein kinase pathway plays a critical role in PAR2-induced endothelial IL-8 production and leukocyte adhesionJIH-HWA GUH ; CHE-MING TENG journal article
742008YC-1 induces heat shock protein 70 expression and prevents oxidized LDL-mediated apoptosis in vascular smooth muscle cellsJIH-HWA GUH ; CHE-MING TENG journal article
752008YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathwayJIH-HWA GUH ; CHE-MING TENG journal article
762007Prazosin displays anticancer activity against human prostate cancers: Targeting DNA and cell cycleJIH-HWA GUH ; TSAI-KUN LI journal article
772007Four new briarane diterpenoids from the gorgonian coral Junceella fragilisJIH-HWA GUH journal article
782007Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathwayLu, P.-H.; JIH-HWA GUH ; Chueh, S.-C.; FAN-LU KUNG ; Kung, F.-L.; Pan, S.-L.; Shen, Y.-C.; Guh, J.-H.journal article
792007Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insultJIH-HWA GUH ; CHUN-JUNG LIN ; TSAI-KUN LI journal article
802007YC-1 inhibits HIF-1 expression in prostate cancer cells: Contribution of Akt/NF-κB signaling to HIF-1α accumulation during hypoxiaJIH-HWA GUH ; CHE-MING TENG journal article
812006Investigation of anti-tumor mechanisms of K2154: Characterization of tubulin isotypes, mitotic arrest and apoptotic machineryJIH-HWA GUH ; FAN-LU KUNG journal article
822006Induction of Fas clustering and apoptosis by coral prostanoid in human hormone-resistant prostate cancer cellsJIH-HWA GUH ; FAN-LU KUNG ; TSAI-KUN LI journal article
832006YC-1 [3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole] inhibits neointima formation in balloon-injured rat carotid through suppression of expressions and activities of matrix metalloproteinases 2 and 9JIH-HWA GUH ; CHE-MING TENG journal article
842005Two new sesquiterpene lactones from Ixeris chinensisJIH-HWA GUH journal article
852005YC-1 suppresses constitutive nuclear factor-κB activation and induces apoptosis in human prostate cancer cellsJIH-HWA GUH ; CHE-MING TENG journal article
862005YC-1 [3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole] inhibits endothelial cell functions induced by angiogenic factors in vitro and angiogenesis in vivo modelsJIH-HWA GUH ; CHE-MING TENG journal article
872005Three new taxane diterpenoids from Taxus sumatranaJIH-HWA GUH ; CHE-MING TENG journal article
882005YC-1 [3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole] exhibits a novel antiproliferative effect and arrests the cell cycle in G 0-G1 in human hepatocellular carcinoma cellsJIH-HWA GUH ; Hui-Ling Chen ; CHE-MING TENG journal article
892004New Cytotoxic Clerodane Diterpenoids from the Leaves and Twigs of Casearia membranaceaJIH-HWA GUH journal article
902004Two new cytotoxic clerodane diterpenoids from Casearia membranaceaJIH-HWA GUH journal article
912004New pentacyclic polyketide dimeric peroxides from a Taiwanese marine sponge Petrosia elasticaJIH-HWA GUH journal article
922004The indazole derivative YD-3 inhibits thrombin-induced vascular smooth muscle cell proliferation and attenuates intimal thickening after balloon injuryJIH-HWA GUH ; CHE-MING TENG journal article
932004YC-1 prevents sodium nitroprusside-mediated apoptosis in vascular smooth muscle cellsJIH-HWA GUH ; CHE-MING TENG journal article
942004Flavonol glycosides and cytotoxic triterpenoids from Alphitonia philippinensisJIH-HWA GUH journal article
952003A novel secobetulinic acid 3,4-lactone from Viburnum aboricolumJIH-HWA GUH ; SHOEI-SHENG LEE journal article
962003Investigation of anticancer mechanism of thiadiazole-based compound in human non-small cell lung cancer A549 cellsJIH-HWA GUH journal article
972002Cardiac glycosides induce resistance to tubulin-dependent anticancer drugs in androgen-independent human prostate cancerJIH-HWA GUH journal article
982002Cardiac glycosides induce resistance to tubulin-dependent anticancer drugs in androgen-independent human prostate cancer.JIH-HWA GUH journal article
992002Inhibition of Ras-mediated cell proliferation by benzyloxybenzaldehyde.JIH-HWA GUH journal article
1002002Inhibition of Ras-mediated cell proliferation by benzyloxybenzaldehydeJIH-HWA GUH journal article
1012001Dual effects of ouabain on the regulation of proliferation and apoptosis in human prostatic smooth muscle cellsJIH-HWA GUH journal article
1022000Effects of ouabain on tension response and [<sup>3</sup>H]noradrenaline release in human prostateJIH-HWA GUH journal article
1032000Effects of ouabain on tension response and [3H]noradrenaline release in human prostateJIH-HWA GUH journal article
1041998Erratum: Mechanism of catecholamine-induced proliferation of vascular smooth muscle cells (Circulation (1996) 94 (547-554))JIH-HWA GUH journal article
1051998Mechanism of anti-proliferation caused by YC-1, an indazole derivative, in cultured rat A10 vascular smooth-muscle cells.JIH-HWA GUH journal article
1061998Retraction: Mechanism of anti-proliferation caused by YC-1, an indazole derivative, in cultured rat A10 vascular smooth-muscle cells (Biochemical Journal (1995) 306 (787-792))JIH-HWA GUH journal article
1071998Antiproliferative effect in human prostatic smooth muscle cells by nitric oxide donorJIH-HWA GUH journal article
1081997Correction: Mechanism of anti-proliferation caused by YC-1, an indazole derivative, in cultured rat A10 vascular smooth-muscle cells (Biochemical Journal (1995) 306 (787-792))JIH-HWA GUH journal article
1091996Mechanism of catecholamine-induced proliferation of vascular smooth muscle cellsJIH-HWA GUH journal article
1101996Ouabain-induced increases in resting tone of human hyperplastic prostate following repeated noradrenaline and electrical field stimulationJIH-HWA GUH journal article
1111995CSH72—A Specific Antagonist of Platelet‐activating Factor in Rabbit PlateletsJIH-HWA GUH journal article
1121995Antiplatelet Effect of Gingerol Isolated from Zingiber officinaleJIH-HWA GUH journal article
1131995Characterization of α<inf>1</inf>‐adrenoceptor subtypes in tension response of human prostate to electrical field stimulationJIH-HWA GUH journal article
1141995Antiplatelet effect of gingerol isolated from Zingiber officinaleJIH-HWA GUH journal article
1151995Pharmacological evaluation of N-methyl-actinodaphnine, a new vascular α-adrenoceptor antagonist, isolated from Illigera luzonensisJIH-HWA GUH journal article
1161995Characterization of α1-adrenoceptor subtypes in tension response of human prostate to electrical field stimulationJIH-HWA GUH journal article
1171995Mechanism of anti-proliferation caused by YC-1, an indazole derivative, in cultured rat A10 vascular smooth-muscle cellsJIH-HWA GUH journal article
1181994Functional identification of α1-adrenoceptor subtypes in human prostate: comparison with those in rat vas deferens and spleenJIH-HWA GUH journal article
1191994(−)‐Discretamine, a selective α<inf>1D</inf>‐adrenoceptor antagonist, isolated from Fissistigma glaucescensJIH-HWA GUH journal article
1201994(-)-Discretamine, a selective α(1D)-adrenoceptor antagonist, isolated from Fissistigma glaucescensJIH-HWA GUH journal article