研究成果



第 1 到 61 筆結果,共 61 筆。

公開日期標題作者來源出版物scopusWOS全文
12024Anticonvulsant effect of equilibrative nucleoside transporters 1 inhibitor in a mouse model of Dravet syndromeHo, Shih-Yin; I-CHUN CHEN ; WEN-CHE TSAI ; Chang, Kai-Chieh; CHUN-JUNG LIN ; Chern, Yijuang; HORNG-HUEI LIOU Hippocampus
22023Physiologically based mechanistic insight into differential risk of valproate hepatotoxicity between children and adults: A focus on ontogeny impactHuang, Yu-Ting; YEN-MING HUANG ; FAN-LU KUNG ; CHUN-JUNG LIN ; TUN JAO ; YUNN-FANG HO CPT: pharmacometrics & systems pharmacology1
32023The Critical Role of Equilibrative Nucleoside Transporter-2 in Modulating Cerebral Damage and Vascular Dysfunction in Mice with Brain Ischemia-ReperfusionChiang, Hui-Ling; Wu, Kuo-Chen; Chen, You-Yin; Ho, Chin-Jui; Wang, Han-Lin; Fu, Yu-Hua; Chen, Wen-Yu; CHUN-JUNG LIN Pharmaceutical research
42023Deletion of equilibrative nucleoside transporter 2 disturbs energy metabolism and exacerbates disease progression in an experimental model of Huntington's diseaseChen, Ching-Ya; Chou, Fang-Yi; Chang, Ya-Gin; Ho, Chin-Jui; Wu, Kuo-Chen; Hsu, Chia-Lin; Chern, Yijuang; CHUN-JUNG LIN Neurobiology of disease
52023Equilibrative Nucleoside Transporter 1 is a Target to Modulate Neuroinflammation and Improve Functional Recovery in Mice with Spinal Cord InjuryChen, Kuan-Yu; Lu, Chiao-Shin; Pang, Cheng-Yoong; Ho, Chin-Jui; Wu, Kuo-Chen; Yang, Hsiu-Wei; Lai, Hsin-Lin; Chern, Yijuang; CHUN-JUNG LIN Molecular neurobiology
62022Ibuprofen treatment ameliorates memory deficits in rats with collagen-induced arthritis by normalizing aberrant MAPK/NF-κB and glutamatergic pathwaysZhang N.-Y.; Wang T.-H.; Chou C.-H.; Wu K.-C.; CHIA-RON YANG ; Kung F.-L.; CHUN-JUNG LIN European Journal of Pharmacology32
72022The Asian Pharmacometrics Network: The historical background, establishment, objectives and roles, and recent activitiesAtsunori Kaibara; Ao Peng; Rujia Xie; YUNN-FANG HO ; CHUN-JUNG LIN ; Lai-San Tham; Surulivelrajan Mallayasamy; Korbtham Sathirakul; Yoke-Lin Lo; Manh Hung Tran; Van Toi Pham; Akhmad Kharis Nugroho; Khin Myo Oo; Bimal Kunwar; Uthpali Mannapperuma; Kimheang Ya; Muhammad Usman; Long Chiau Ming; Kyungsoo ParkCPT: Pharmacometrics and Systems Pharmacology11
82021Changes of blood-brain-barrier function and transfer of amyloid beta in rats with collagen-induced arthritisLai, Po Hsuan; Wang, Ting Hsuan; Zhang, Nai You; Wu, Kuo Chen; JANE CHUNG-CHEN YAO ; CHUN-JUNG LIN Journal of Neuroinflammation1211
92021Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathyChang, Ching-Pang; Chang, Ya-Gin; Chuang, Pei-Yun; Nguyen, Thi Ngoc Anh; Wu, Kuo-Chen; Chou, Fang-Yi; Cheng, Sin-Jhong; Chen, Hui-Mei; Jin, Lee-Way; Carvalho, Kevin; Huin, Vincent; Buée, Luc; Liao, Yung-Feng; CHUN-JUNG LIN ; Blum, David; Chern, YijuangActa Neuropathologica Communications66
102021Amelioration of lipopolysaccharide-induced memory impairment in equilibrative nucleoside transporter-2 knockout mice is accompanied by the changes in glutamatergic pathwaysWu, Kuo-Chen; Lee, Chih-Yu; Chern, Yijuang; CHUN-JUNG LIN Brain, Behavior, and Immunity65
112020Equilibrative Nucleoside Transporters-1 Inhibitors Act as Anti-epileptic Agents by Inhibiting Glutamatergic TransmissionHo S.-Y.; Chen I.-C.; Chang K.-C.; Lin H.-R.; Tsai C.-W.; CHUN-JUNG LIN ; Liou H.-H.Frontiers in Neuroscience76
122020Deletion of equilibrative nucleoside transporter-2 protects against lipopolysaccharide-induced neuroinflammation and blood-brain barrier dysfunction in miceWu K.-C.; Lee C.-Y.; Chou F.-Y.; Chern Y.; CHUN-JUNG LIN Brain, Behavior, and Immunity2220
132019The regulation of drug-metabolizing enzymes and membrane transporters by inflammation: Evidences in inflammatory diseases and age-related disordersWu K.-C.; CHUN-JUNG LIN Journal of Food and Drug Analysis6054
142019Down-regulation of natural resistance-associated macrophage protein-1 (Nramp1) is associated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)/1-methyl-4-phenylpyridinium (MPP + )-induced α-synuclein accumulation and neurotoxicityWu K.-C.; HORNG-HUEI LIOU ; Lee C.-Y.; CHUN-JUNG LIN Neuropathology and Applied Neurobiology1512
152018Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer’s DiseaseLee, Chia-Chia; Chang, Ching-Pang; CHUN-JUNG LIN ; Lai, Hsing-Lin; Kao, Yu-Han; Cheng, Sin-Jhong; Chen, Hui-Mei; Liao, Yu-Ping; Faivre, Emilie; Buee, Luc; Blum, David; Fang, J.-M. ; HUI-MEI CHEN Molecular Neurobiology3535
162017Differential changes in the pharmacokinetics of statins in collagen-induced arthritis ratsCHUN-JUNG LIN Biochemical Pharmacology1715
172017Targeting ENT1 and adenosine tone for the treatment of Huntington's diseaseKao, Yu-Han; Lin, Meng-Syuan; Chen, Chiung-Mei; Wu, Yih-Ru; Chen, Hui-Mei; Lai, Hsing-Lin; Chern, Yijuang; CHUN-JUNG LIN Human Molecular Genetics3129
182017Rifamycin SV MMX for the treatment of traveler’s diarrheaSHU-WEN LIN ; CHUN-JUNG LIN ; JYH-CHIN YANG Expert Opinion on Pharmacotherapy42
192017The critical role of Nramp1 in degrading α-synuclein oligomers in microglia under iron overload conditionWu K.-C.; HORNG-HUEI LIOU ; Kao Y.-H.; Lee C.-Y.; CHUN-JUNG LIN Neurobiology of Disease1211
202015Effects of lipopolysaccharide on the expression of plasma membrane monoamine transporter (PMAT) at the blood-brain barrier and its implications to the transport of neurotoxinsWu, Kuo-Chen; Lu, Ya-Hsuan; Peng, Yi-Hsuan; LIH-CHING HSU ; CHUN-JUNG LIN Journal of Neurochemistry2315
212015Biotransformed product, genistein 7-O-phosphate, enhances the oral bioavailability of genisteinWang, Shang-Ta; Fang, Ting-Fang; Hsu, Chen; Chen, Chia-Hao; CHUN-JUNG LIN ; NAN-WEI SU Journal of Functional Foods1718
222015Decreased expression of organic cation transporters, Oct1 and Oct2, in brain microvessels and its implication to MPTP-induced dopaminergic toxicity in aged miceCHUN-JUNG LIN Journal of Cerebral Blood Flow and Metabolism3022
232015High-dose dual therapy is superior to standard first-line or rescue therapy for helicobacter pylori infectionJYH-CHIN YANG ; CHUN-JUNG LIN ; Wang H.-L.; Chen J.-D.; Kao J.Y.; CHIA-TUNG SHUN ; Lu C.-W.; BOR-RU LIN ; MING-JIUM SHIEH ; MING-CHU CHANG ; YU-TING CHANG ; SHU-CHEN WEI ; Lin L.-C.; Yeh W.-C.; Kuo J.-S.; CHIEN-CHIH TUNG ; Leong Y.-L.; Wang T.-H.; Wong J.-M.Clinical Gastroenterology and Hepatology153131
242014Treatment of Helicobacter pylori infection: Current status and future conceptsJYH-CHIN YANG ; Lu C.-W.; CHUN-JUNG LIN World Journal of Gastroenterology130119
252014Tamiphosphor monoesters as effective anti-influenza agentsChen, C.-L.; Lin, T.-C.; Wang, S.-Y.; Shie, J.-J.; Tsai, K.-C.; Cheng, Y.-S.E.; Jan, J.-T.; Lin, C.-J.; Fang, J.-M.; Wong, C.-H.; CHUN-JUNG LIN ; JIM-MIN FANG European Journal of Medicinal Chemistry2323
262013Synthesis and biological evaluation of novel C-aryl D-glucofuranosides as sodium-dependent glucose co-transporter 2 inhibitorsLin, Tzung-Sheng; Liw, Ya-Wen; Song, Jen-Shin; Hsieh, Tsung-Chih; Yeh, Hsien-Wei; LIH-CHING HSU ; CHUN-JUNG LIN ; Wu, Szu-Huei; PI-HUI LIANG Bioorganic and Medicinal Chemistry1311
272013Development of a novel non-radioactive cell-based method for the screening of SGLT1 and SGLT2 inhibitors using 1-NBDGChang, Hung-Chi; Yang, Su-Fu; Huang, Ching-Chun; Lin, Tzung-Sheng; PI-HUI LIANG ; CHUN-JUNG LIN ; LIH-CHING HSU Molecular BioSystems1616
282013Improved dissolution rate and oral bioavailability of lovastatin in red yeast rice productsChen C.-H.; JYH-CHIN YANG ; Uang Y.-S.; CHUN-JUNG LIN International Journal of Pharmaceutics6452
292012Hyperglycemia induced down-regulation of renal P-glycoprotein expressionCHUN-JUNG LIN European Journal of Pharmacology1612
302012Interaction between red yeast rice and CYP450 enzymes/P-glycoprotein and its implication for the clinical pharmacokinetics of lovastatinChen C.-H.; Uang Y.-S.; Wang S.-T.; JYH-CHIN YANG ; CHUN-JUNG LIN Evidence-based Complementary and Alternative Medicine3219
312012Differential inhibitory effects of proton pump inhibitors on the metabolism and antiplatelet activities of clopidogrel and prasugrelChen C.-H.; JYH-CHIN YANG ; Uang Y.-S.; CHUN-JUNG LIN Biopharmaceutics and Drug Disposition1915
322011MUC1 expression is elevated in severe preeclamptic placentas and suppresses trophoblast cell invasion via β1-integrin signalingMING-KWANG SHYU ; Chen C.-W.; NENG-YU LIN ; Liao W.-C.; CHI-HAU CHEN ; CHUN-JUNG LIN ; Huang H.-C.; Lee Jr. J.; Huang M.-J.; Tseng G.-F.; JIN-CHUNG SHIH ; CHIEN-NAN LEE ; FON-JOU HSIEH ; MIN-CHUAN HUANG Journal of Clinical Endocrinology and Metabolism2525
332011Hypoxia-mediated down-regulation of OCTN2 and PPARrα expression in human placentas and in BeWo cellsChang T-T.; MING-KWANG SHYU ; MIN-CHUAN HUANG ; Hsu C-C.; Yeh S-Y.; MEI-RU CHEN ; CHUN-JUNG LIN Molecular Pharmaceutics2322
342011Role of omeprazole dosage and cytochrome P450 2C19 genotype in patients receiving omeprazole-amoxicillin dual therapy for Helicobacter pylori eradicationJYH-CHIN YANG ; Wang H.-L.; Chern H.-D.; CHIA-TUNG SHUN ; BOR-RU LIN ; CHUN-JUNG LIN ; Wang T.-H.Pharmacotherapy4233
352011A new drug design targeting the adenosinergic system for huntington's diseaseHuang N.-K.; Lin J.-H.; Lin J.-T.; Lin C.-I.; Liu E.M.; CHUN-JUNG LIN ; Chen W.-P.; Shen Y.-C.; Chen H.-M.; Chen J.-B.; Lai H.-L.; Yang C.-W.; Chiang M.-C.; Wu Y.-S.; Chang C.; Chen J.-F.; Fang J.-M.; Lin Y.-L.; Chern Y.PLoS ONE7263
362010Cellular localization of the organic cation transporters, OCT1 and OCT2, in brain microvessel endothelial cells and its implication for MPTP transport across the blood-brain barrier and MPTP-induced dopaminergic toxicity in rodentsCHUN-JUNG LIN ; Tai Y.; Huang M.-T.; Tsai Y.-F.; Hsu H.-J.; KAI-YUAN TZEN ; HORNG-HUEI LIOU Journal of Neurochemistry9680
372010CYP2C19 genotypes in the pharmacokinetics/pharmacodynamics of proton pump inhibitor-based therapy of Helicobacter pylori infectionJYH-CHIN YANG ; CHUN-JUNG LIN Expert Opinion on Drug Metabolism and Toxicology4842
382009Change in P-glycoprotein and caveolin protein expression in brain striatum capillaries in New Zealand Obese mice with type 2 diabetesWu, Kuo-Chen; Pan H.-J.; HSIANG-SHU YIN ; MEI-RU CHEN ; SHAO-CHUN LU ; CHUN-JUNG LIN Life Sciences2924
392009Regulation of Protein Expression and Function of OCTN2 in Forskolin-Induced Syncytialization in BeWo CellsHuang F.-D.; FAN-LU KUNG ; Tseng Y.-C.; MEI-RU CHEN ; Chan H.-S.; CHUN-JUNG LIN Placenta1512
402009Pharmacokinetic- pharmacodynamic analysis of the role of CYP2C19 genotypes in short-term rabeprazole-based triple therapy against Helicobacter pyloriJYH-CHIN YANG ; Yang Y.-F.; Uang Y.-S.; CHUN-JUNG LIN ; Wang T.-H.British Journal of Clinical Pharmacology1414
412009Aspect-ratio-dependent ultra-low reflection and luminescence of dry-etched Si nanopillars on Si substratePai, Y.-H.; Meng, F.-S.; Lin, C.-J.; Kuo, H.-C.; Hsu, S.-H.; Chang, Y.-C.; GONG-RU LIN ; Lin, Chun-Jung Nanotechnology1817
422008Functional evaluation of polymorphisms in the human ABCB1 gene and the impact on clinical responses of antiepileptic drugsHung, Chin-Chuan; Chen, Chih-Chuan; CHUN-JUNG LIN ; HORNG-HUEI LIOU Pharmacogenetics and Genomics5449
432008Association of galactose single-point test levels and phenytoin metabolic polymorphisms with gingival hyperplasia in patients receiving long-term phenytoin therapyCHUN-JUNG LIN ; Yen M.-F.; Hu O.Y.-P.; Lin M.-S.; Hsiong C.-H.; Hung, Chin-Chuan; HORNG-HUEI LIOU Pharmacotherapy76
442008Characterization of Si nanorods by spectroscopic ellipsometry with efficient theoretical modelingHsu, S.-H.; Liu, E.-S.; Chang, Y.-C.; Hilfiker, J.N.; Kim, Y.D.; Kim, T.J.; Lin, C.-J.; Lin, G.-R.; GONG-RU LIN ; Lin, Chun-Jung Physica Status Solidi (A) Applications and Materials Science3331
452008Enhancement of glucose transporter expression of brain endothelial cells by vascular endothelial growth factor derived from glioma exposed to hypoxiaYeh W.-L.; CHUN-JUNG LIN ; WEN-MEI FU Molecular Pharmacology128124
462007Interaction between nicotine and MPTP/MPP+ in rat brain endothelial cellsHORNG-HUEI LIOU ; Hsu, Hao-Jui; Tsai Y.-F.; Shih, Chin-Yu; Chang, Yu-Chia; CHUN-JUNG LIN Life Sciences1413
472007Interaction of flavonoids and intestinal facilitated glucose transportersCHUN-JUNG LIN Planta Medica4736
482007Inhibition of hypoxia-induced increase of blood-brain barrier permeability by YC-1 through the antagonism of HIF-1α accumulation and VEGF expressionYeh W.-L.; Lu D.-Y.; CHUN-JUNG LIN ; Liou H.-C.; WEN-MEI FU Molecular Pharmacology132122
492007Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insultYeh T.-C.; Chiang P.-C.; TSAI-KUN LI ; Hsu J.-L.; CHUN-JUNG LIN ; Wang S.-W.; Peng C.-Y.; JIH-HWA GUH Biochemical Pharmacology123110
502006Inhibition of intestinal glucose uptake by aporphines and secoaporphinesCHUN-JUNG LIN ; Chen C.-H.; Liu F.-W.; Kang J.-J.; Chen C.-K.; Lee S.-L.; SHOEI-SHENG LEE Life Sciences1010
512005Complex haplotypic effects of the ABCB1 gene on epilepsy treatment responseHung, Chin-Chuan; Tai J.J.; CHUN-JUNG LIN ; MING-JEN LEE ; HORNG-HUEI LIOU Pharmacogenomics118102
522005Tissue distribution of arsenic species in rabbits after single and multiple parenteral administration of arsenic trioxide: Tissue accumulation and the reversibility after washout are tissue-selectiveCHUN-JUNG LIN ; MEI-HWAN WU ; Hsueh Y.-M.; Sun S.S.-M.; ANN-LII CHENG Cancer Chemotherapy and Pharmacology2318
532005Oxygen defect and Si nanocrystal dependent white-light and near-infrared electroluminescence of Si-implanted and plasma-enhanced chemical-vapor deposition-grown Si-rich SiO <inf>2</inf>Lin, G.-R.; Lin, C.-J.; Lin, C.-K.; Chou, L.-J.; Lin, Gong-Ru ; Lin, Chun-Jung ; GONG-RU LIN Journal of Applied Physics198195
542004Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphismsHung, Chin-Chuan; CHUN-JUNG LIN ; Chen, Chih-Chuan; Chang C.-J.; HORNG-HUEI LIOU Therapeutic Drug Monitoring11593
552004Interaction between Anticonvulsants and Human Placental Carnitine TransporterWu S.-P.; MING-KWANG SHYU ; HORNG-HUEI LIOU ; Gau C.-S.; CHUN-JUNG LIN Epilepsia3928
562003Direct cardiac effects of As2O3 in rabbits: Evidence of reversible chronic toxicity and tissue accumulation of arsenicals after parenteral administrationMEI-HWAN WU ; CHUN-JUNG LIN ; Chen C.-L.; MING-JAI SU ; Sun S.S.-M.; ANN-LII CHENG Toxicology and Applied Pharmacology2823
572003Time-dependent amplified pharmacokinetic and pharmacodynamic responses of rabeprazole in cytochrome P450 2C19 poor metabolizersCHUN-JUNG LIN ; JYH-CHIN YANG ; Uang Y.-S.; Chern H.-D.; Wang T.-H.Pharmacotherapy2116
581999Glycylsarcosine uptake in rabbit renal brush border membrane vesicles isolated from outer cortex or outer medulla: Evidence for heterogeneous distribution of oligopeptide transportersCHUN-JUNG LIN AAPS Journal
591999Competitive inhibition of glycylsarcosine transport by enalapril in rabbit renal brush border membrane vesicles: Interaction of ACE inhibitors with high-affinity H+/peptide symporterCHUN-JUNG LIN Pharmaceutical Research3231
601998Noncompetitive inhibition of glycylsarcosine transport by quinapril in rabbit renal brush border membrane vesicles: Effect on high-affinity peptide transporterCHUN-JUNG LIN Journal of Pharmacology and Experimental Therapeutics
611996Intestinal absorption studies on peptide mimetic α-methyldopa prodrugsCHUN-JUNG LIN Journal of Pharmacy and Pharmacology