研究成果


第 1 到 49 筆結果，共 49 筆。

公開日期標題作者來源出版物scopusWOS全文
12024Loss of LECT2 promotes ovarian cancer progression by inducing cancer invasiveness and facilitating an immunosuppressive environmentCHIN-JUI WU ; Pan, Ke-Fan; Chen, Ji-Qing; Tao, Yu -Chen; Liu, Yu-Cheng; Chen, Bo-Rong; Hsu, Ching; MING-YANG WANG ; BOR-CHING SHEU ; Hsiao, Michael; KUO-TAI HUA ; LIN-HUNG WEI Oncogene0
22023Multiple impacts of Naa10p on cancer progression: Molecular functions and clinical prospectsHo, Kuo-Hao; Pan, Ke-Fan; TSU-YAO CHENG ; Chien, Ming-Hsien; KUO-TAI HUA Biochimica et biophysica acta. Reviews on cancer
32023The RNA-binding protein KSRP aggravates malignant progression of clear cell renal cell carcinoma through transcriptional inhibition and post-transcriptional destabilization of the NEDD4L ubiquitin ligaseYang, Yi-Chieh; Lin, Yung-Wei; Lee, Wei-Jiunn; Lai, Feng-Ru; Ho, Kuo-Hao; Chu, Chih-Ying; KUO-TAI HUA ; Chen, Ji-Qing; Tung, Min-Che; Hsiao, Michael; Wen, Yu-Ching; Chien, Ming-HsienJournal of Biomedical Science1
42022Naa10p promotes cell invasiveness of esophageal cancer by coordinating the c-Myc and PAI1 regulatory axisPan, Ke-Fan; Liu, Yu-Cheng; Hsiao, Michael; TSU-YAO CHENG ; KUO-TAI HUA Cell death & disease33
52022In vitro genotoxicity assessment and 28-day repeated dose oral toxicity study of steady-calcium formula in ratsChang, Ting Yu; Lan, Kuo Cheng; KUO-TAI HUA ; SHING-HWA LIU Toxicology Reports10
62022Proteoglycan Endocan: A multifaceted therapeutic target in CancerPan, Ke-Fan; Yang, Yi-Chieh; Lee, Wei-Jiunn; KUO-TAI HUA ; Chien, Ming-HsienBiochimica et Biophysica Acta. Reviews on Cancer87
72022Discovery and characterization of a monoclonal antibody targeting a conformational epitope of IL-6/IL-6Rα to inhibit IL-6/ IL-6Rα/gp130 hexameric signaling complex formationChou, Chun-Chi; KUO-TAI HUA ; Chen, Min-Wei; CHIN-JUI WU ; CHUN-HUA HSU ; JANN-TAY WANG ; Hsiao, Michael; LING-HUNG WEI mAbs43
82021Histone Methyltransferase G9a-Promoted Progression of Hepatocellular Carcinoma Is Targeted by Liver-Specific Hsa-miR-122Yuan, Lan-Ting; Lee, Wei-Jiunn; Yang, Yi-Chieh; Chen, Bo-Rong; CHING-YAO YANG ; Chen, Min-Wei; Chen, Ji-Qing; Hsiao, Michael; Chien, Ming-Hsien; KUO-TAI HUA Cancers128
92021Direct interaction of β-catenin with nuclear ESM1 supports stemness of metastatic prostate cancerPan K.-F.; Lee W.-J.; Chou C.-C.; Yang Y.-C.; Chang Y.-C.; Chien M.-H.; Hsiao M.; KUO-TAI HUA EMBO Journal1615
102020Suppressing migration and invasion of H1299 lung cancer cells by honokiol through disrupting expression of an HDAC6-mediated matrix metalloproteinase 9Pai J.-T.; Hsu C.-Y.; Hsieh Y.-S.; Tsai T.-Y.; KUO-TAI HUA ; Weng M.-S.Food Science and Nutrition1514
112020Stabilization of ADAM9 by N-α-acetyltransferase 10 protein contributes to promoting progression of androgen-independent prostate cancerLin Y.-W.; Wen Y.-C.; Chu C.-Y.; Tung M.-C.; Yang Y.-C.; KUO-TAI HUA ; Pan K.-F.; Hsiao M.; Lee W.-J.; Chien M.-H.Cell Death and Disease1510
122020Circulating proteoglycan endocan mediates EGFR-driven progression of non-small cell lung cancerYang Y.-C.; Pan K.-F.; Lee W.-J.; Chang J.-H.; Tan P.; Gu C.-C.; Chang W.-M.; Yang S.-F.; Hsiao M.; KUO-TAI HUA ; Chien M.-H.Cancer Research1413
132020Overexpression of PSAT1 promotes metastasis of lung adenocarcinoma by suppressing the IRF1-IFNγ axisChan Y.-C.; Chang Y.-C.; Chuang H.-H.; Yang Y.-C.; Lin Y.-F.; Huang M.-S.; Hsiao M.; Yang C.-J.; KUO-TAI HUA Oncogene3127
142019Cabozantinib (XL184) and R428 (BGB324) Inhibit the Growth of Esophageal Squamous Cell Carcinoma (ESCC)Yang P.-W.; Liu Y.-C.; Chang Y.-H.; Lin C.-C.; PEI-MING HUANG ; KUO-TAI HUA ; JANG-MING LEE ; MIN-SHU HSIEH Frontiers in Oncology1214
152018Circulating Interleukin-6 is Associated with Prognosis and Genetic Polymorphisms of MIR608 in Patients with Esophageal Squamous Cell CarcinomaYang P.-W.; PEI-MING HUANG ; Yong L.-S.; Chang Y.-H.; Wu C.-W.; KUO-TAI HUA ; MIN-SHU HSIEH ; JANG-MING LEE Annals of Surgical Oncology1212
162018Leukocyte cell-derived chemotaxin 2 retards non-small cell lung cancer progression through antagonizing MET and EGFR activitiesHung W.-Y.; Chang J.-H.; Cheng Y.; Chen C.-K.; Chen J.-Q.; KUO-TAI HUA ; Cheng C.-W.; Hsiao M.; Chung C.-L.; Lee W.-J.; Chien M.-H.Cellular Physiology and Biochemistry1211
172018N-α-acetyltransferase 10 protein promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomasChien M.-H.; Lee W.-J.; Yang Y.-C.; Tan P.; Pan K.-F.; Liu Y.-C.; Tsai H.-C.; Hsu C.-H.; Wen Y.-C.; Hsiao M.; KUO-TAI HUA Cancer Letters2525
182018Pyruvate kinase M2 promotes pancreatic ductal adenocarcinoma invasion and metastasis through phosphorylation and stabilization of PAK2 proteinTSU-YAO CHENG ; Yang Y.-C.; HSIU-PO WANG ; YU-WEN TIEN ; CHIA-TUNG SHUN ; Huang H.-Y.; Hsiao M.; KUO-TAI HUA Oncogene5245
192018Nuclear translocation of PKM2/AMPK complex sustains cancer stem cell populations under glucose restriction stressYang Y.-C.; Chien M.-H.; Liu H.-Y.; Chang Y.-C.; Chen C.-K.; Lee W.-J.; Kuo T.-C.; Hsiao M.; KUO-TAI HUA ; TSU-YAO CHENG Cancer Letters5050
202018miR-519d promotes melanoma progression by downregulating EphA4KUO-TAI HUA ; Hong J.-B.; YI-SHUAN SHEEN ; Huang H.-Y.; Huang Y.-L.; JAU-SHIUH CHEN ; YI-HUA LIAO Cancer Research2119
212017Corrigendum to “Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells” [Cancer Letters 383 (2016) 282–294] (S0304383516306243) (10.1016/j.canlet.2016.10.012)Kuo T.-C.; Chen C.-K.; KUO-TAI HUA ; Yu P.; Lee W.-J.; Chen M.-W.; YUNG-MING JENG ; Chien M.-H.; Kuo K.-T.; Hsiao M.; Kuo M.-L.Cancer Letters00
222017Erratum: miR-107 promotes tumor progression by targeting the let-7 microRNA in mice and humans (The Journal of clinical investigation (2011) 121 9 (3442-3455) PII: 92099)Chen P.-S.; Su J.-L.; Cha S.-T.; Tarn W.-Y.; Wang M.-Y.; Hsu H.-C.; Lin M.-T.; CHIA-YU CHU ; KUO-TAI HUA ; CHIUNG-NIEN CHEN ; Kuo T.-C.; KING-JEN CHANG ; Hsiao M.; Chang Y.-W.; JIN-SHING CHEN ; PAN-CHYR YANG ; Kuo M.-L.The Journal of clinical investigation06
2320173′UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinomaKUO-TAI HUA ; Liu Y.-F.; CHIA-LANG HSU ; TSU-YAO CHENG ; CHING-YAO YANG ; Chang J.-S.; Lee W.-J.; Hsiao M.; Juan H.-F. ; Chien M.-H.; Yang S.-F.Scientific Reports4945
242017Histone methyltransferase G9a drives chemotherapy resistance by regulating the glutamate-cysteine ligase catalytic subunit in head and neck squamous cell carcinomaLiu C.-W.; KUO-TAI HUA ; Li K.-C.; HSIANG-FONG KAO ; RUEY-LONG HONG ; JENG-YUH KO ; Hsiao M.; Kuo M.-L.; CHING-TING TAN Molecular Cancer Therapeutics4240
252017The STAT3-miRNA-92-Wnt signaling pathway regulates spheroid formation and malignant progression in ovarian cancerChen M.-W.; Yang S.-T.; Chien M.-H.; KUO-TAI HUA ; CHIN-JUI WU ; Hsiao S.M.; Lin H.; Hsiao M.; Su J.-L.; LING-HUNG WEI Cancer Research121111
262017KSRP suppresses cell invasion and metastasis through miR-23a-mediated EGR3 mRNA degradation in non-small cell lung cancerChien M.-H.; Lee W.-J.; Yang Y.-C.; Li Y.-L.; Chen B.-R.; TSU-YAO CHENG ; Yang P.-W.; Wang M.-Y.; Jan Y.-H.; Lin Y.-K.; JANG-MING LEE ; Hsiao M.; JIN-SHING CHEN ; KUO-TAI HUA Biochimica et Biophysica Acta - Gene Regulatory Mechanisms2826
272016Lipocalin 2 prevents oral cancer metastasis through carbonic anhydrase IX inhibition and is associated with favourable prognosisLin C.-W.; Yang W.-E.; Lee W.-J.; KUO-TAI HUA ; Hsieh F.-K.; Hsiao M.; Chen C.-C.; Chow J.-M.; Chen M.-K.; Yang S.-F.; Chien M.-H.Carcinogenesis6059
282016Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cellsKuo T.-C.; Chen C.-K.; KUO-TAI HUA ; Yu P.; Lee W.-J.; Chen M.-W.; YUNG-MING JENG ; Chien M.-H.; Kuo K.-T.; Hsiao M.; Kuo M.-L.Cancer Letters4443
292016Akt activation correlates with snail expression and potentially determines the recurrence of prostate cancer in patients at stage T2 after a radical prostatectomyChen W.-Y.; KUO-TAI HUA ; Lee W.-J.; Lin Y.-W.; Liu Y.-N.; Chen C.-L.; Wen Y.-C.; Chien M.-H.International Journal of Molecular Sciences33
302016Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90-EGFR associationYang Y.-C.; TSU-YAO CHENG ; Huang S.-M.; Su C.-Y.; Yang P.-W.; JANG-MING LEE ; Chen C.-K.; Hsiao M.; KUO-TAI HUA ; Kuo M.-L.Oncogene4239
312016Inhibition of VEGF 165/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesisChen C.-K.; Yu W.-H.; TSU-YAO CHENG ; Chen M.-W.; Su C.-Y.; Yang Y.-C.; Kuo T.-C.; MING-TSAN LIN ; Huang Y.-C.; Hsiao M.; KUO-TAI HUA ; Hung M.-C.; Kuo M.-L.Scientific Reports2521
322015Correction: Soluble AXL: A possible circulating biomarker for neurofibromatosis type 1 related tumor burdenJohansson G.; Peng P.-C.; Huang P.-Y.; Chien H.-F.; KUO-TAI HUA ; Kuo M.-L.; Chen C.-T.PLoS ONE00
332015GIT1 promotes lung cancer cell metastasis through modulating Rac1/Cdc42 activity and is associated with poor prognosisChang, J.-S.; Su, C.-Y.; Yu, W.-H.; Lee, W.-J.; Liu, Y.-P.; Lai, T.-C.; Jan, Y.-H.; Yang, Y.-F.; Shen, C.-N.; Shew, J.-Y.; Lu, J.; Yang, C.-J.; Huang, M.-S.; Lu, P.-J.; Lin, Y.-F.; Kuo, M.-L.; KUO-TAI HUA ; Hsiao, M.Oncotarget4037
342015Honokiol from Magnolia spp. induces G1 arrest via disruption of EGFR stability through repressing HDAC6 deacetylated Hsp90 function in lung cancer cellsLiou, S.-F.; KUO-TAI HUA ; Hsu, C.-Y.; Weng, M.-S.Journal of Functional Foods1817
352015Keap1-Nrf2 interaction suppresses cell motility in lung adenocarcinomas by targeting the S100P proteinChien M.-H.; Lee W.-J.; Hsieh F.-K.; Li C.-F.; TSU-YAO CHENG ; Wang M.-Y.; JIN-SHING CHEN ; Chow J.-M.; Jan Y.-H.; Hsiao M.; KUO-TAI HUA ; Kuo M.-L.Clinical Cancer Research3937
362015The H3K9 Methyltransferase G9a Represses E-cadherin and is Associated with Myometrial Invasion in Endometrial CancerHsiao S.-M; Chen M.-W; CHI-AN CHEN ; Chien M.-H; KUO-TAI HUA ; Hsiao M; Kuo M.-L; LING-HUNG WEI Annals of Surgical Oncology3128
372014Cyr61/CTGF/Nov family proteins in gastric carcinogenesisTSU-YAO CHENG ; MING-SHIANG WU ; KUO-TAI HUA ; Kuo M.-L.; MING-TSAN LIN World Journal of Gastroenterology3127
382014The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasisKUO-TAI HUA ; Wang M.-Y; Chen M.-W; LING-HUNG WEI ; Chen C.-K; Ko C.-H; YUNG-MING JENG ; Sung P.-L; Jan Y.-H; Hsiao M; Kuo M.-L; MEN-LUH YEN Molecular Cancer121113
392014Soluble AXL: a possible circulating biomarker for neurofibromatosis type 1 related tumor burdenJohansson G.; Peng P.-C.; Huang P.-Y.; Chien H.-F.; KUO-TAI HUA ; Kuo M.-L.; Chen C.-T.; MING-JEN LEE PloS one1820
402014Formyl peptide receptor 1 expression is associated with tumor progression and survival in gastric cancerTSU-YAO CHENG ; MING-SHIANG WU ; Lin J.-T.; MING-TSAN LIN ; CHIA-TUNG SHUN ; KUO-TAI HUA ; Kuo M.-L.Anticancer Research3433
412013Hispolon induces apoptosis through JNK1/2-mediated activation of a caspase-8, -9, and -3-dependent pathway in acute myeloid leukemia (AML) cells and inhibits AML xenograft tumor growth in vivoHsiao, P.-C.; Hsieh, Y.-H.; Chow, J.-M.; Yang, S.-F.; Hsiao, M.; KUO-TAI HUA ; Lin, C.-H.; Chen, H.-Y.; Chien, M.-H.Journal of Agricultural and Food Chemistry4036
422013Inhibition of metastatic potential in breast carcinoma in vivo and in vitro through targeting VEGFRs and FGFRsChien M.-H; Lee L.-M; Hsiao M; LING-HUNG WEI ; Chen C.-H; Lai T.-C; KUO-TAI HUA ; Chen M.-W; Sun C.-M; Kuo M.-L.Evidence-based Complementary and Alternative Medicine108
432012Annexin A1 is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the formyl peptide receptor/extracellular signal-regulated kinase/integrin beta-1-binding protein 1 pathwayTSU-YAO CHENG ; MING-SHIANG WU ; Lin J.-T.; MING-TSAN LIN ; CHIA-TUNG SHUN ; Huang H.-Y.; KUO-TAI HUA ; Kuo M.-L.Cancer8379
442011FOXO3a-dependent mechanism of E1A-induced chemosensitizationSu, J.-L; Cheng, X; Yamaguchi, H; Chang, Y.-W; Hou, C.-F; Lee, D.-F; Ko, H.-W; KUO-TAI HUA ; Wang, Y.-N; Hsiao, M; Chen, P.B; Hsu, J.-M; Bast Jr., R.C; Hortobagyi, G.N; Hung, M.-C.Cancer Research3838
452011N-α-Acetyltransferase 10 Protein Suppresses Cancer Cell Metastasis by Binding PIX Proteins and Inhibiting Cdc42/Rac1 ActivityKUO-TAI HUA ; CHING-TING TAN ; Johansson G.; JANG-MING LEE ; Yang P.-W.; Lu H.-Y.; Chen C.-K.; Su J.-L.; Chen P.B.; Wu Y.-L.; Chi C.-C.; Kao H.-J.; Shih H.-J.; Chen M.-W.; Chien M.-H.; Chen P.-S.; Lee W.-J.; TSU-YAO CHENG ; Rosenberger G.; Chai C.-Y.; Yang C.-J.; Huang M.-S.; Lai T.-C.; Chou T.-Y.; Hsiao M.; Kuo M.-L.Cancer Cell8580
462010H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAMChen M.-W.; KUO-TAI HUA ; Kao H.-J.; Chi C.-C.; LING-HUNG WEI ; Johansson G.; Shiah S.-G.; Chen P.-S.; YUNG-MING JENG ; TSU-YAO CHENG ; Lai T.-C.; Chang J.-S.; Jan Y.-H.; Chien M.-H.; Yang C.-J.; Huang M.-S.; Hsiao M.; Kuo M.-L.Cancer Research300279
472009Beneficial effects of different tea flowers against human breast cancer MCF-7 cellsWay, T.-D.; Lin, H.-Y.; KUO-TAI HUA ; Lee, J.-C.; Li, W.-H.; Lee, M.-R.; Shuang, C.-H.; Lin, J.-K.Food Chemistry3129
482007CTGF enhances the motility of breast cancer cells via an integrin-αvβ3-ERK1/2-dependent S100A4-upregulated pathwayPO-HUANG LEE ; CHIUNG-NIEN CHEN ; KUO-TAI HUA ; Su J.-L.; Hong C.-C.; Chuang S.-E.; Chen M.-W.; Hua K.-T.; Wu Y.-L.; Cha S.-T.; Babu M.S.; KING-JEN CHANG ; Kuo M.-L.Journal of Cell Science131127
492006Pentagalloylglucose inhibits estrogen receptor α by lysosome-dependent depletion and modulates ErbB/PI3K/Akt pathway in human breast cancer MCF-7 cellsKUO-TAI HUA ; Way, T.-D.; Lin, J.-K.Molecular Carcinogenesis3128