研究成果



第 1 到 42 筆結果,共 42 筆。

公開日期標題作者來源出版物scopusWOS全文
12023Generation of induced pluripotent stem cells (IBMSi027-A) from a patient with hearing loss carrying WFS1 c.2051C > T (p.Ala684Val) variantChan, Yen-Hui; Tsai, Cheng-Yu; Ho, Chang-Han; Lu, Ying-Chang; PEI-HSUAN LIN ; TA-CHING CHEN ; YOU-TZUNG CHEN ; Huang, Cheng-Yen; TIEN-CHEN LIU ; Hsu, Chuan-Jen; CHEN-CHI WU Stem Cell Research00
22023miR-194 Up-Regulates Cholesterol 7 Alpha-Hydroxylase Expression via β-Catenin Signaling and Aggravates Cholestatic Liver DiseasesChen, Po-Chun; Hsu, Chien-Peng; Wang, Sheng-Ya; Wu, Tsai-Yen; Lin, Yu-Jyun; YOU-TZUNG CHEN ; SHU-HAO HSU The American Journal of Pathology10
32022Targeting ER protein TXNDC5 in hepatic stellate cell mitigates liver fibrosis by repressing non-canonical TGFβ signallingHung, Chen-Ting; TUNG-HUNG SU ; Chen, Yen-Ting; Wu, Yueh-Feng; YOU-TZUNG CHEN ; SUNG-JAN LIN ; SHUEI-LIONG LIN ; KAI-CHIEN YANG Gut1011
42022Generation of induced pluripotent stem cells from a patient with hearing loss carrying OPA1 c.1468T>C (p.Cys490Arg) variantChan, Yen-Hui; Ho, Chang-Han; Tsai, Cheng-Yu; Lu, Ying-Chang; PEI-HSUAN LIN ; TA-CHING CHEN ; YOU-TZUNG CHEN ; Huang, Cheng-Yen; TIEN-CHEN LIU ; Hsu, Chuan-Jen; CHEN-CHI WU ; Hsu, Chuan-JenStem Cell Research11
52022Exploration of the niche effect on tumor satellite budding of head and neck cancer with biomimicking modelingCHUN-NAN CHEN ; Wang, Ju-Chu; YOU-TZUNG CHEN ; TSUNG-LIN YANG Biomaterials00
62021Wdhd1 is essential for early mouse embryogenesisFan, Hsiang-Hsuan; Lee, Kuo-Hong; YOU-TZUNG CHEN ; Lin, Li-Jyuan; TSUNG-LIN YANG ; SHU-WHA LIN ; Yu, I-ShingBiochimica et Biophysica Acta (BBA) - Molecular Cell Research55
72021A Preconditioning Strategy to Augment Retention and Engraftment Rate of Donor Cells during Hepatocyte TransplantationHsu, Yu-Chen; Yu, I-Shing; Tsai, Yu-Fei; YAO-MING WU ; YOU-TZUNG CHEN ; Sheu, Jin-Chuan; SHU-WHA LIN Transplantation22
82021In vitro genome editing rescues parkinsonism phenotypes in induced pluripotent stem cells-derived dopaminergic neurons carrying LRRK2 p.G2019S mutationChang, Kuo-Hsuan; Huang, Cheng-Yen; Ou-Yang, Chih-Hsin; Ho, Chang-Han; Lin, Han-Yi; Hsu, Chia-Lang; YOU-TZUNG CHEN ; Chou, Yu-Chi; Chen, Yi-Jing; Chen, Ying; Lin, Jia-Li; Wang, Ji-Kuan; Lin, Pei-Wen; Lin, Ying-Ru; MIAO-HSIA LIN ; CHI-KANG TSENG ; CHIN-HSIEN LIN Stem Cell Research and Therapy1813
92019P53 ICE CRIM mouse: A tool to generate mutant allelic series in somatic cells and germ lines for cancer studiesFan H.-H.; Shing Yu I.; Lin Y.-H.; Wang S.-Y.; Liaw Y.-H.; PEI-LUNG CHEN ; TSUNG-LIN YANG ; SHU-WHA LIN ; YOU-TZUNG CHEN FASEB Journal11
102019Embryonic Cul4b is important for epiblast growth and location of primitive streak layer cellsChen, Chun-Yu; Yu, I-Shing; Pai, Chen-Hsueh; Lin, Chien-Yu; Lin, Shu-Rung; YOU-TZUNG CHEN ; SHU-WHA LIN PloS one21
112018Generation of induced pluripotent stem cells from a patient with hearing loss carrying GJB2 p.V37I mutationChan, Yen Hui; Cheng, Yen Fu; YOU-TZUNG CHEN ; Huang, Cheng Yen; CHIN-HSIEN LIN ; Hu, Chin Ju; Lu, Ying Chang; Chen-Chi Wu ; Hsu, Chuan JenStem Cell Research32
122018Facilitating In Vivo Articular Cartilage Repair by Tissue-Engineered Cartilage Grafts Produced From Auricular ChondrocytesWong C.-C.; Chen C.-H.; Chiu L.-H.; Tsuang Y.-H.; Bai M.-Y.; Chung R.-J.; Lin Y.-H.; FON-JOU HSIEH ; YOU-TZUNG CHEN ; TSUNG-LIN YANG American Journal of Sports Medicine2318
132018A simple and efficient feeder-free culture system to up-scale iPSCs on polymeric material surface for use in 3D bioprintingWong, C.-W.; YOU-TZUNG CHEN ; CHUNG-LIANG CHIEN ; Yu, T.-Y.; Rwei, S.-P.; SHAN-HUI HSU Materials Science and Engineering C109
142018Application of three-dimensional collagen scaffolds to recapitulate and monitor the dynamics of epithelial-mesenchymal transition during tumor satellite formation of head and neck cancerChun-Nan Chen ; YOU-TZUNG CHEN ; TSUNG-LIN YANG Biomaterials1110
152017The data of establishing a three-dimensional culture system for in vitro recapitulation and mechanism exploration of tumor satellite formation during cancer cell transitionChun-Nan Chen ; YOU-TZUNG CHEN ; TSUNG-LIN YANG Data in Brief30
162017Subcellular localization of survivin determines its function in cardiomyocytesTsang T.-J.; Hsueh Y.-C.; Wei E.I.; Lundy D.J.; Cheng B.; YOU-TZUNG CHEN ; SHOEI-SHEN WANG ; Hsieh P.C.H.Theranostics1212
172017PARP1 controls KLF4-mediated telomerase expression in stem cells and cancer cellsHsieh M.-H; YOU-TZUNG CHEN ; Chen Y.-T; Lee Y.-H; Lu J; CHUNG-LIANG CHIEN ; HSIN-FU CHEN ; HONG-NERNG HO ; Yu C.-J; Wang Z.-Q; SHU-CHUN TENG Nucleic Acids Research3535
182017Mobilizing transit-amplifying cell-derived ectopic progenitors prevents hair loss from chemotherapy or radiation therapyHuang W.-Y.; SHIH-FAN LAI ; HSIEN-YI CHIU ; Chang M.; Plikus M.V.; CHIH-CHIEH CHAN ; YOU-TZUNG CHEN ; PO-NIEN TSAO ; TSUNG-LIN YANG ; Lee, Hsuan-Shu ; Chi P. ; SUNG-JAN LIN Cancer Research3025
192017Single-Stage Cartilage Repair Using Platelet-Rich Fibrin Scaffolds With Autologous Cartilaginous GraftsWong C.-C.; Chen C.-H.; Chan W.P.; Chiu L.-H.; Ho W.-P.; FON-JOU HSIEH ; YOU-TZUNG CHEN ; TSUNG-LIN YANG American Journal of Sports Medicine3431
202015Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant dravet syndrome model during developmentTsai M.-S.; Lee M.-L.; Chang C.-Y.; Fan H.-H.; Yu I.-S.; YOU-TZUNG CHEN ; You J.-Y.; Chen C.-Y.; Chang F.-C.; Hsiao J.H.; Khorkova O.; HORNG-HUEI LIOU ; Yanagawa Y.; LI-JEN LEE ; SHU-WHA LIN Neurobiology of Disease3934
212014Genetic analysis of CARD14 in non-familial pityriasis rubra pilaris: A case seriesJIN-BON HONG ; PEI-LUNG CHEN ; YOU-TZUNG CHEN ; TSEN-FANG TSAI Acta Dermato-Venereologica129
222014A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cellsJIN-BON HONG ; Chou F.-J.; Ku A.T.; Fan H.-H.; Lee T.-L.; Huang Y.-H.; TSUNG-LIN YANG ; Su I.-C.; Yu I.-S.; SHU-WHA LIN ; CHUNG-LIANG CHIEN ; HONG-NERNG HO ; YOU-TZUNG CHEN PLoS ONE44
232013The mesenchymal architecture of the cranial mesoderm of mouse embryos is disrupted by the loss of Twist1 function.You-Tzung Chen; Loebel D.A.F.; Jones V.J.; Hor A.C.C.; Braithwaite A.W.; YOU-TZUNG CHEN ; Behringer R.R.; Tam P.P.L.3837
242013Controlling branching structure formation of the salivary gland by the degree of chitosan deacetylationHsiao Y.-C.; Chun-Nan Chen ; YOU-TZUNG CHEN ; TSUNG-LIN YANG Acta Biomaterialia1815
252012Regionalized Twist1 activity in the forelimb bud drives the morphogenesis of the proximal and preaxial skeleton.You-Tzung Chen; Hor A.C.C.; Bildsoe H.; Jones V.; YOU-TZUNG CHEN ; Behringer R.R.; Tam P.P.L.2221
262012Rescue of the genetically engineered Cul4b mutant mouse as a potential model for human X-linked mental retardationChen C.-Y.; Tsai M.-S.; Lin C.-Y.; Yu I.-S.; YOU-TZUNG CHEN ; Lin S.-R.; Juan L.-W.; Hsu H.-M.; LI-JEN LEE ; SHU-WHA LIN Human Molecular Genetics4443
272012R26R-GR: A Cre-Activable Dual Fluorescent Protein Reporter MouseYOU-TZUNG CHEN ; Tsai M.-S.; TSUNG-LIN YANG ; Ku A.T.; Huang K.-H.; Huang C.-Y.; Chou F.-J.; Fan H.-H.; JIN-BON HONG ; Yen S.-T.; Wang W.-L.; Lin C.-C.; Hsu Y.-C.; KANG-YI SU ; Su I.-C.; Jang C.-W.; Behringer R.R.; Favaro R.; Nicolis S.K.; CHUNG-LIANG CHIEN ; SHU-WHA LIN ; Yu I.-S.PLoS ONE1310
282011Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.You-Tzung Chen; Yeung S.-C.J.; Chen J.; Iwakuma T.; Su C.-H.; Chen B.; Qu C.; Zhang F.; YOU-TZUNG CHEN ; Lin Y.-L.; Lee D.-F.; Jin F.; Zhu R.; Shaikenov T.; Sarbassov D.; Sahin A.; Wang H.; Wang H.; Lai C.-C.; Tsai F.-J.; Lozano G.; Lee M.-H.8787
292011The impact of compositional topography of amniotic membrane scaffold on tissue morphogenesis of salivary glandHsiao Y.-C.; Lee H.-W.; YOU-TZUNG CHEN ; Tai-Horng Young ; TSUNG-LIN YANG Biomaterials2522
302010Twist1 activity thresholds define multiple functions in limb development.You-Tzung Chen; Weiner S.J.; YOU-TZUNG CHEN ; Lu B.C.; Costantini F.; Behringer R.R.; Laufer E.5251
312010Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb.You-Tzung Chen; Sui P.; Dong A.; Hassell J.; Cserjesi P.; YOU-TZUNG CHEN ; Behringer R.R.; Sun X.5556
322010PiggyBac transposon-mediated, reversible gene transfer in human embryonic stem cellsYOU-TZUNG CHEN ; Furushima K; Hou P.-S; Ku A.T; Deng J.M; Jang C.-W; Fang H; Adams H.P; Kuo M.-L; HONG-NERNG HO ; CHUNG-LIANG CHIEN ; Behringer R.R.Stem Cells and Development3230
332009Requirement for Twist1 in frontonasal and skull vault development in the mouse embryo.You-Tzung Chen; Loebel D.A.F.; Jones V.J.; YOU-TZUNG CHEN ; Behringer R.R.; Tam P.P.L.7168
342008H1 and H9 human embryonic stem cell lines are heterozygous for the ABO locus.YOU-TZUNG CHEN ; Dejosez M.; Zwaka T.P.; Behringer R.R.76
352007Generation of a Twist1 conditional null allele in the mouseYOU-TZUNG CHEN ; Akinwunmi P.O.; Jian M.D.; Tam O.H.; Behringer R.R.Genesis4545
362006Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium.You-Tzung Chen; Bialek P.; YOU-TZUNG CHEN ; Rached M.-T.; Groner Y.; Behringer R.R.; Ornitz D.M.; Karsenty G.133128
372006BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning.Ovchinnikov D.A.; Selever J.; Wang Y.; YOU-TZUNG CHEN ; Mishina Y.; Martin J.F.; Behringer R.R.7672
382006Gene expression profiles in developing nephrons using Lim1 metanephric mesenchyme-specific conditional mutant mice.YOU-TZUNG CHEN ; Kobayashi A.; Kwan K.M.; Johnson R.L.; Behringer R.R.260
392004Inducible gene trapping with drug-selectable markers and Cre/loxP to identify developmentally regulated genes.YOU-TZUNG CHEN ; Liu P.; Bradley A.2017
402004Bigenic Cre/loxP, puDeltatk conditional genetic ablation.YOU-TZUNG CHEN ; Levasseur R.; Vaishnav S.; Karsenty G.; Bradley A.1411
412000A new positive/negative selectable marker, pu?tk, for use in embryonic stem cellsYOU-TZUNG CHEN ; Bradley A.Genesis70
421996Detection of baculovirus associated with white spot syndrome (WSBV) in penaeid shrimps using polymerase chain reactionYou-Tzung Chen; Leu J.-H.; Ho C.-H.; Chen C.-H.; Peng S.-E.; YOU-TZUNG CHEN ; Chou C.-M.; Yeh P.-Y.; Huang C.-J.; Chou H.-Y.; Wang C.-H.; Kou G.-H.428409