研究成果


第 1 到 37 筆結果，共 37 筆。

公開日期標題作者來源出版物scopusWOS全文
12022Translation initiation site of mRNA is selected through dynamic interaction with the ribosomeChen Y.-L; JIN-DER WEN Proceedings of the National Academy of Sciences of the United States of America43
22021Formation of frameshift-stimulating RNA pseudoknots is facilitated by remodeling of their folding intermediatesHsu, Chiung-Fang; Chang, Kai-Chun; Chen, Yi-Lan; Hsieh, Po-Szu; Lee, An-I; Tu, Jui-Yun; Chen, Yu-Ting; JIN-DER WEN Nucleic Acids Research87
32021Programmed −1 ribosomal frameshifting from the perspective of the conformational dynamics of mRNA and ribosomesChang, Kai Chun; JIN-DER WEN Computational and Structural Biotechnology Journal77
42020The diversity of Shine-Dalgarno sequences sheds light on the evolution of translation initiationWen J.-D; Kuo S.-T; HSIN-HUNG CHOU ; Wen, J.-D. RNA Biology99
52020Global fitness landscapes of the Shine-Dalgarno sequenceKuo, Syue-Ting; Jahn, Ruey-Lin; Cheng, Yuan-Ju; Chen, Yi-Lan; Lee, Yun-Ju; Hollfelder, Florian; Wen, Jin-Der; Stathes Paganis ; JIN-DER WEN ; HSIN-HUNG CHOU Genome Research1412
62019Resolution-exchanged structural modeling and simulations jointly unravel that subunit rolling underlies the mechanism of programmed ribosomal frameshiftingChang, Kai-Chun; Salawu, Emmanuel Oluwatobi; Chang, Yuan-Yu; JIN-DER WEN ; Yang, Lee-WeiBioinformatics77
72018Unfolding Intermediate of mRNA Pseudoknot Correlates with Ribosomal FrameshiftingChang, Kai-Chun; Hsieh, Po-Szu; Lee, An-Yi; Salawu, Emmanuel; Lin, You-Hsin; Chen, Yu-Ting; JIN-DER WEN Biophysical Journal01
82017Coordination among tertiary base pairs results in an efficient frameshift-stimulating RNA pseudoknotChen, Yu-Ting; Chang, Kai-Chun; Hu, Hao-Teng; Chen, Yi-Lan; Lin, You-Hsin; Hsu, Chiung-Fang; Chang, Cheng-Fu; Chang, Kung-Yao; JIN-DER WEN Nucleic Acids Research1311
92015Ribosome Excursions during mRNA Translocation Mediate Broad Branching of Frameshift PathwaysYan, Shannon; JIN-DER WEN ; Bustamante, Carlos; Tinoco, IgnacioCell8276
102015Functional importance of mobile ribosomal proteinsChang, Kai-Chun; JIN-DER WEN ; Yang, Lee-WeiBioMed Research International85
112014Direct measurement of the mechanical work during translocation by the ribosomeLiu, Tingting; Kaplan, Ariel; Alexander, Lisa; Yan, Shannon; JIN-DER WEN ; Lancaster, Laura; Wickersham, Charles E.; Fredrick, Kurt; Noller, Harry; Tinoco, Ignacio; Bustamante, Carlos J.eLife6064
122014Characterization of Ribosomal Bypassing through a 50-Nt mRNA Untranslated GapChang, Kai-Chun; Jheng, Yao-Wei; JIN-DER WEN Biophysical Journal00
132014Deciphering Ribosomal Frameshifting DynamicsYan, Shannon; JIN-DER WEN ; Lancaster, Laura; Noller, Harry; Bustamante, Carlos; Tinoco, IgnacioBiophysical Journal00
142014Folding a stable RNA pseudoknot through rearrangement of two hairpin structuresWu, Yi-Ju; Wu, Cheng-Han; Yeh, Athena Yi-Chun; JIN-DER WEN Nucleic Acids Research1412
152013Single-Molecule Study on Structural Rearrangement of the 5'UTR of rpsO Messenger RNAWu, Yi-Ju; Wu, Cheng-Han; JIN-DER WEN Biophysical Journal00
162012Deciphering Ribosomal Frameshifting DynamicsShannon Yan; JIN-DER WEN ; Laura Lancaster; Harry Noller; Carlos Bustamante; Ignacio Tinoco Jr.Biophysical Journal00
172012Modelling Programmed Ribosomal Frameshifting with Elastic Network Model and Linear Response TheoryChang, Kai-Chun; JIN-DER WEN ; Yang, Lee-WeiBiophysical Journal00
182011The ribosome uses two active mechanisms to unwind messenger RNA during translationQu, Xiaohui; JIN-DER WEN ; Lancaster, Laura; Noller, Harry F.; Bustamante, Carlos; Tinoco, IgnacioNature229226
192010解開遺傳密碼的解碼者－核醣體溫進德 化學0
202010Single-Molecule Study of Programmed Ribosomal FrameshiftingJIN-DER WEN ; Laura Lancaster; Harry Noller; Carlos Bustamante; Ignacio TinocoBiophysical Journal00
212009Simulation and analysis of single-ribosome translationTinoco Jr., Ignacio; JIN-DER WEN Physical Biology3530
222008Following translation by single ribosomes one codon at a timeJIN-DER WEN ; Lancaster, Laura; Hodges, Courtney; Zeri, Ana-Carolina; Yoshimura, Shige H.; Noller, Harry F.; Bustamante, Carlos; Tinoco Jr., IgnacioNature381372
232008Measured and calculated CD spectra of G-quartets stacked with the same or opposite polaritiesGray, Donald M.; JIN-DER WEN ; Gray, Carla W.; Repges, Rudolf; Repges, Charlotte; Raabe, Gerhard; Fleischhauer, JörgChirality187176
242007Force unfolding kinetics of RNA using optical tweezers. I. Effects of experimental variables on measured resultsJIN-DER WEN ; Manosas, Maria; Li, Pan T. X.; Smith, Steven B.; Bustamante, Carlos; Ritort, Felix; Tinoco Jr., IgnacioBiophysical Journal117113
252007Single-molecule mechanical unfolding and folding of a pseudoknot in human telomerase RNAChen, Gang; JIN-DER WEN ; Tinoco Jr., IgnacioRNA6162
262007Force unfolding kinetics of RNA using optical tweezers. II. Modeling experimentsManosas, Maria; JIN-DER WEN ; Li, Pan T.X.; Smith, Steve B.; Bustamante, Carlos J.; Tinoco, Ignacio; Ritort, FélixBiophysical Journal5655
272004Ff Gene 5 Single-Stranded DNA-Binding Protein Assembles on Nucleotides Constrained by a DNA HairpinJIN-DER WEN ; Gray, Donald M.Biochemistry1113
282004Selection of genomic sequences that bind tightly to Ff gene 5 protein: primer-free genomic SELEX.JIN-DER WEN ; Gray, Donald MNucleic acids research5857
292002The Ff gene 5 single-stranded DNA-binding protein binds to the transiently folded form of an intramolecular G-quadruplexJIN-DER WEN ; Gray, Donald M.Biochemistry2729
302002CD of single-stranded, double-stranded, and G-quartet nucleic acids in complexes with a single-stranded DNA-binding proteinGray, Donald M.; Gray, Carla W.; Mou, Tung-Chung; JIN-DER WEN Enantiomer1913
312001SELEX selection of high-affinity oligonucleotides for bacteriophage Ff gene 5 proteinJIN-DER WEN ; Gray, Carla Winlund; Gray, Donald M.Biochemistry3031
321999Evidence from CD spectra and melting temperatures for stable Hoogsteen-paired oligomer duplexes derived from DNA and hybrid triplexesHashem, Gihan M.; JIN-DER WEN ; Do, Quynh; Gray, Donald M.Nucleic Acids Research2426
331999Increased nitric oxide synthase mRNA expression in the renal medulla of water-deprived ratsShin, Shyi-Jang; Lai, Feng-Jie; JIN-DER WEN ; Lin, Shiu-Ru; Hsieh, Ming-Chia; Hsiao, Pi-Jung; Tsai, Juei-HsiungKidney International3436
341998The naturally occurring PKC inhibitor sphingosine and tumor promoter phorbol ester potentially induce tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase FA/GSK-3alpha in a common signalling pathwayLee, S.-C.; Kuan, C.-Y.; Wen, Z.-D. ; Yang, S.-D.Journal of Protein Chemistry7
351998Increased renal ANP synthesis, but decreased or unchanged cardiac ANP synthesis in water-deprived and salt-restricted ratsShin, Shyi-Jang; JIN-DER WEN ; Chen, I.-Hsuan; Lai, Feng-Jie; Hsieh, Ming-Chia; Hsieh, Tusty-Jiuan; Tan, Mian-Shin; Tsai, Juei-HsiungKidney International1817
361998Increased C-type natriuretic peptide mRNA expression in the kidney of diabetic ratsShin, Shyi Jang; JIN-DER WEN ; Lee, Yaujiunn; Chen, I. Hsuan; Tsai, Juei HsiungJournal of Endocrinology2018
371994Tumor promoter phorbol ester reversibly modulates tyrosine dephosphorylation/inactivation of protein kinase FA/GSK-3 alpha in A431 cellsShiaw-Der Yang; Jau-Song Yu; Zin-Der Wen Journal of Cellular Biochemistry 0