研究成果


第 1 到 63 筆結果，共 63 筆。

公開日期標題作者來源出版物scopusWOS全文
12024Isotropic multi-scale neuronal reconstruction from high-ratio expansion microscopy with contrastive unsupervised deep generative modelsChang, Gary Han; Wu, Meng Yun; Yen, Ling Hui; Huang, Da Yu; Lin, Ya Hui; Luo, Yi Ru; Liu, Ya Ding; Xu, Bin; Leong, Kam W.; WEN-SUNG LAI ; Chiang, Ann Shyn; Wang, Kuo Chuan; CHIN-HSIEN LIN ; Wang, Shih Luen; Chu, Li AnComputer Methods and Programs in Biomedicine
22021Functional neuroanatomy and neural oscillations during social eavesdropping in male golden hamstersLiu, C.-Y.; WEN-SUNG LAI Hormones and Behavior22
32021Not just a bystander: The emerging role of astrocytes and research tools in studying cognitive dysfunctions in schizophreniaChang C.-Y; Luo D.-Z; Pei J.-C; MING-CHE KUO ; Hsieh Y.-C; Lai W.-S.; WEN-SUNG LAI International Journal of Molecular Sciences149
42021A Reconfigurable Differential-to-Single-Ended Autonomous Current Adaptation Buffer Amplifier Suitable for Biomedical ApplicationsWEN-SUNG LAI IEEE Transactions on Biomedical Circuits and Systems11
52021Directly and Indirectly Targeting the Glycine Modulatory Site to Modulate NMDA Receptor Function to Address Unmet Medical Needs of Patients With SchizophreniaPei J.-C; Luo D.-Z; Gau S.-S; Chang C.-Y; WEN-SUNG LAI Frontiers in Psychiatry1315
62020P50, N100, and P200 Auditory Sensory Gating Deficits in Schizophrenia PatientsShen, C.-L.; Chou, T.-L.; Lai, W.-S.; MING-HSIEN HSIEH ; CHEN-CHUNG LIU ; CHIH-MIN LIU ; TAI-LI CHOU ; WEN-SUNG LAI Frontiers in Psychiatry3228
72020Lithium for schizophrenia: supporting evidence from a 12-year, nationwide health insurance database and from Akt1-deficient mouse and cellular modelsLuo, D.-Z.; Chang, C.-Y.; Huang, T.-R.; Studer, V.; Wang, T.-W.; TSUNG-REN HUANG ; WEN-SUNG LAI Scientific Reports108
82020Firing activity of locus coeruleus noradrenergic neurons decreases in necdin-deficient mice, an animal model of Prader-Willi syndromeWu, R.-N.; Hung, W.-C.; Chen, C.-T.; Tsai, L.-P.; Lai, W.-S.; Min, M.-Y.; MING-YUAN MIN ; WEN-SUNG LAI Journal of Neurodevelopmental Disorders86
92019Therapeutic potential and underlying mechanism of sarcosine (N-methylglycine) in N-methyl-D-aspartate (NMDA) receptor hypofunction models of schizophreniaPei, J.-C.; Hung, W.-L.; Lin, B.-X.; Shih, M.-H.; Lu, L.-Y.; Luo, D.-Z.; Tai, H.-C. ; Studer, V.; Min, M.-Y.; Lai, W.-S.; WEN-SUNG LAI Journal of Psychopharmacology119
102017Misfortune may be a blessing in disguise: Fairness perception and emotion modulate decision makingLiu, H.-H.; Hwang, Y.-D.; MING-HSIEN HSIEH ; Hsu, Y.-F.; WEN-SUNG LAI ; YUNG-FONG HSU Psychophysiology33
112016Ophiocordyceps formosana improves hyperglycemia and depression-like behavior in an STZ-induced diabetic mouse modelHuang, C.-W.; Hong, T.-W.; Wang, Y.-J.; Chen, K.-C.; Pei, J.-C.; Chuang, T.-Y. ; Lai, W.-S.; Tsai, S.-H.; Chu, R.; Chen, W.-C.; Sheen, L.-Y.; Takahashi, S.; Ding, S.-T. ; TANG-LONG SHEN ; WEN-SUNG LAI ; Sheen L.-Y. BMC Complementary and Alternative Medicine1916
122016Neuronal firing patterns outweigh circuitry oscillations in parkinsonian motor controlMING-KAI PAN ; Kuo, S.-H.; CHUN-HWEI TAI ; Liou, J.-Y.; Pei, J.-C.; Chang, C.-Y.; Wang, Y.-M.; Liu, W.-C.; Wang, T.-R.; WEN-SUNG LAI ; CHUNG-CHIN KUO Journal of Clinical Investigation3028
132016Akting up in the GABA hypothesis of schizophrenia: Akt1 deficiency modulates GABAergic functions and hippocampus-dependent functionsChang, C.-Y.; Chen, Y.-W.; Wang, T.-W.; Lai, W.-S.; WEN-SUNG LAI Scientific Reports1916
142016Repeated, Intermittent social defeat across the entire juvenile period resulted in behavioral, Physiological, Hormonal, Immunological, and neurochemical alterations in young adult male golden hamstersYu, W.-C.; Liu, C.-Y.; Lai, W.-S.; WEN-SUNG LAI Frontiers in Behavioral Neuroscience910
152015Impaired cognition and cerebral glucose regulation are associated with astrocyte activation in the parenchyma of metabolically stressed APPswe/PS1dE9 miceYeh, C.-W.; Yeh, S.H.-H.; Shie, F.-S.; Lai, W.-S.; Liu, H.-K.; Tzeng, T.-T.; Tsay, H.-J.; WEN-SUNG LAI Neurobiology of Aging2827
162015Investigation of gene effects and epistatic interactions between Akt1 and neuregulin 1 in the regulation of behavioral phenotypes and social functions in genetic mouse models of schizophreniaHuang, C.-H.; Pei, J.-C.; Luo, D.-Z.; Chen, C.; Chen, Y.-W.; WEN-SUNG LAI Frontiers in Behavioral Neuroscience2213
172015Effects of affective arousal on choice behavior, reward prediction errors, and feedback-related negativities in human reward-based decision makingLiu, Hong-Hsiang; Hsieh, Ming H.; YUNG-FONG HSU ; WEN-SUNG LAI Frontiers in Psychology217
182014Assessing Schizophrenia-relevant Cognitive and Social Deficits in Mice: A Selection of Mouse Behavioral Tasks and Potential Therapeutic CompoundsWen-Sung Lai; Chia-Yuan Chang; Wan-Rong Wong; Ju-Chun Pei; Ya-Shan Chen; Wei-Li Hung; WEN-SUNG LAI CPD1310
192014A new method for studying social eavesdropping using male golden hamstersLai, W.-S.; Yu, W.-C.; Liu, C.-Y.; Kuo, M.-T.; WEN-SUNG LAI Physiology and Behavior55
202014以增強學習模型與貝氏因子探討酬賞預測誤差的男女差異及性格相關李家慈; 賴文崧; 徐永豐; YUNG-FONG HSU ; WEN-SUNG LAI 中華心理學刊 00
212014Inferring reward prediction errors in patients with schizophrenia: A dynamic reward task for reinforcement learningLi, C.-T.; CHIH-MIN LIU ; WEN-SUNG LAI ; YUNG-FONG HSU Frontiers in Psychology811
222014A sex- and region-specific role of Akt1 in the modulation of methamphetamine-induced hyperlocomotion and striatal neuronal activity: Implications in schizophrenia and methamphetamine-induced psychosisChen, Y.-W.; Kao, H.-Y.; Min, M.-Y.; MING-YUAN MIN ; WEN-SUNG LAI Schizophrenia Bulletin1615
232014Deranged NMDAergic cortico-subthalamic transmission underlies parkinsonian motor deficitsMING-KAI PAN ; CHUN-HWEI TAI ; Liu, W.-C.; Pei, J.-C.; WEN-SUNG LAI ; CHUNG-CHIN KUO Journal of Clinical Investigation2726
242014Distinct phenotypes of new transmembrane-domain neuregulin 1 mutant mice and the rescue effects of valproate on the observed schizophrenia-related cognitive deficitsPei, J.-C.; CHIH-MIN LIU ; WEN-SUNG LAI Frontiers in Behavioral Neuroscience2321
252014Assessing Schizophrenia-Relevant Cognitive and Social Deficits in Mice: A selection of Mouse behavioral Tasks and Potential Therapeutic CompoundsLai, W.-S.; Chang, C.-Y.; Wong, W.-R.; Pei, J.-C.; Chen, Y.-S.; Hung, W.-L.; WEN-SUNG LAI Current Pharmaceutical Design13
262014Phenotypic characterization of C57BL/6J mice carrying the Disc1 gene from the 129S6/SvEv strainJuan, L.-W.; Liao, C.-C.; WEN-SUNG LAI ; Chang, C.-Y.; Pei, J.-C.; Wong, W.-R.; CHIH-MIN LIU ; HAI-GWO HWU ; LI-JEN LEE Brain Structure and Function2726
272013Aromatic L-Amino Acid Decarboxylase (AADC) Is Crucial for Brain Development and Motor FunctionsShih, De-Fen; Hsiao, Chung-Der; MING-YUAN MIN ; WEN-SUNG LAI ; Yang, Chianne-Wen; WANG-TSO LEE ; SHYH-JYE LEE PLoS ONE2825
282013Antidepressant-like effect of lemon essential oil is through a modulation in the levels of norepinephrine, dopamine, and serotonin in mice: Use of the tail suspension testHao, C.-W.; Lai, W.-S.; Ho, C.-T.; WEN-SUNG LAI ; Sheen L.-Y. Journal of Functional Foods4034
292013Effects of maternal immune activation on adult neurogenesis in the subventricular zone-olfactory bulb pathway and olfactory discriminationLiu, Y.-H.; Lai, W.-S.; Tsay, H.-J.; Wang, T.-W.; WEN-SUNG LAI Schizophrenia Research3026
302012Akt1 deficiency modulates reward learning and reward prediction error in miceChen, Y.-C.; Chen, Y.-W.; Hsu, Y.-F.; Chang, W.-T.; CHUHSING KATE HSIAO ; Min, M.-Y.; WEN-SUNG LAI ; YUNG-FONG HSU Genes, Brain and Behavior109
312012Active coping with stress suppresses glucose metabolism in the rat hypothalamusOno, Y.; Lin, H.-C.; KAI-YUAN TZEN ; Chen, H.-H.; Yang, P.-F.; WEN-SUNG LAI ; Chen, J.-H.; Onozuka, M.; CHEN-TUNG YEN Stress2121
322011Akt1 deficiency causes alterations in hippocampal neuromorphology and hippocampus-dependent cognitive functionYi-Wen Chen; Wan-Ting Chang; Wen-Sung Lai; WEN-SUNG LAI Neuroscience Research 00
332011The behavioral consequence and functional neuroanatomy of social learning in male Syrian hamstersWEN-SUNG LAI Neuroscience Research 00
342011Evaluation of attentional functions in AKT1 mouse model of schizophrenia using five-choice serial reaction time taskWEN-SUNG LAI Neuroscience Research 00
352011Active coping prevents stress-increased glucose metabolism in the rat hypothalamusOno, Yumie; Lin, Hsiao-Chun; Chen, Hui-Hsing; Yang, Pai-Feng; Lai, Wen-Sung; Chen, Jyh-Horng; Onozuka, Minoru; Tzen, Kai-Yuan; WEN-SUNG LAI ; CHEN-TUNG YEN Neuroscience Research00
362011Characterization of behavioural responses in different test contexts after a single social defeat in male golden hamsters (Mesocricetus auratus)Huang, C.-H.; Kuo, M.-T.; WEN-SUNG LAI Behavioural Processes1413
372011A biological validation procedure for the measurements of fecal outputs and fecal cortisol metabolites in male Syrian hamstersKuo, M.-T.; Jong, D.-S.; Jong, De-Shien ; Lai, Wen-Sung ; WEN-SUNG LAI Chinese Journal of Physiology66
382011BEHAVIORAL PHENOTYPING OF V-AKT MURINE THYMOMA VIRAL ONCOGENE HOMOLOG 1-DEFICIENT MICE REVEALS A SEX-SPECIFIC PREPULSE INHIBITION DEFICIT IN FEMALES THAT CAN BE PARTIALLY ALLEVIATED BY GLYCOGEN SYNTHASE KINASE-3 INHIBITORS BUT NOT BY ANTIPSYCHOTICSChen, Y.W.; WEN-SUNG LAI Neuroscience2018
392010An investigation of neonatal immune challenge in NRG1 mutant miceSin-Ru Jhang; Yao-Chu Chen; Wan-Ting Chang; Ju-Chun Pei; Wen-Sung Lai; WEN-SUNG LAI Neuroscience Research 00
402010Effects of periadolescent exposure to methamphetamine on adult behavioral performances in male Akt1 deficient miceWEN-SUNG LAI Neuroscience Research 00
412010The potential role of Akt1 in the regulation of pentylenetetrazol-induced convulsion and the expression of GABAergic interneuronsWEN-SUNG LAI Neuroscience Research 00
422010Effects of long-term social subjugations during puberty on adult behavioral performance: using male hamsters as a modelWEN-SUNG LAI Neuroscience Research 00
432010An investigation of neuromorphological alterations in the auditory cortex of Akt1 knockout miceYi-Wen Chen; Ju-Chun Pei; Wen-Sung Lai; WEN-SUNG LAI Neuroscience Research 00
442010Behavioral and cognitive characterizations of AKT1-NRG1 single and double mutant miceChing-Hsun Huang; Yi-Wen Chen; Ju-Chun Pei; Wen-Sung Lai; WEN-SUNG LAI Neuroscience Research 00
452010Kyanite formation and element fractionation in the high-al eclogites from the sulu UHP metamorphic terraneLi, Chia-Tzu; Liu, Yung-Hsin; MEI-FEI CHU ; Lai, Wen-Sung ; Yang, Huai-Jen; Zhang, Jianxin; Liu, Chih-Min ; Shau, Yen-Hong; Hsu, Yung-Fong ; Chu, Mei-Fei ; Iizuka, Yoshiyuki; Yu, Shu-Cheng; 劉智民 Terrestrial, Atmospheric and Oceanic Sciences33
462010Distribution of large terminal inputs from the primary and secondary somatosensory cortices to the dorsal thalamus in the rodentChia-Chi Liao; Ruei-Feng Chen; Wen-Sung Lai; Rick C. S. Lin; Chen-Tung Yen; RUEI-FENG CHEN ; WEN-SUNG LAI ; CHEN-TUNG YEN Journal of Comparative Neurology3327
472010Longitudinal characterization of behavioral phenotypes in NRG1 mutant micePei, Ju-Chun; Chen, Yi-Wen; Chen, Yao-Chu; Huang, Ching-Hsun; Jhang, Sin-ru; WEN-SUNG LAI Neuroscience Research01
482010Behavioural phenotyping of dopamine transporter knockdown mice using local small interference RNAChen, Y.-C.; WEN-SUNG LAI Behavioural Brain Research44
492009Behavioral consequences of local dopamine transporter knockdown in the mouse brain using small interfering RNAYao-chu Chen; Yi-Wen Chen; Wen-Hao Tsai; Jia-Yuan Chang; Wen-Sung Lai; WEN-SUNG LAI Neuroscience Research 00
502009The regulatory role of Akt1 in dopamine dependent behavior in male and female miceWEN-SUNG LAI Neuroscience Research 00
512009The effects of social defeat experience on anxiety-like behavior and social memory in male hamsterWEN-SUNG LAI Neuroscience Research 00
522009An investigation of eavesdropping and consequential changes in golden hamstersKuo, Ming-tsung; Yu, Wei-Chun; Shang, Cheng-I.; Huang, Ching-Hsun; WEN-SUNG LAI Neuroscience Research00
532008Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse modelKimberly L Stark et al.; Xu, B.; Bagchi, A.; WEN-SUNG LAI ; Liu, H.; Hsu, R.; Wan, X.; Pavlidis, P.; Mills, A.A.; Karayiorgou, M.; Gogos, J.A.Nature Genetics491450
542007探尋個體辨識的行為與神經機制 - 利用倉鼠作為研究模式　（新制多年期第1年）賴文崧 
552007利用倉鼠探討個體辨識與社會記憶之神經生理機制賴文崧 
562007Nogo receptor 1 (RTN4R) as a candidate gene for schizophrenia: Analysis using human and mouse genetic approachesHsu, R.; Woodroffe, A.; Lai, W.-S.; Cook, M.N.; Mukai, J.; Dunning, J.P.; Swanson, D.J.; Roos, J.L.; Abecasis, G.R.; Karayiorgou, M.; WEN-SUNG LAI PLoS ONE5450
572006Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioningLai, W.-S.; Xu, B.; Westphal, K.G.C.; Paterlini, M.; Olivier, B.; Pavlidis, P.; Karayiorgou, M.; Gogos, J.A.; WEN-SUNG LAI Proceedings of the National Academy of Sciences of the United States of America131126
582005Recognition of familiar individuals in golden hamsters: A new method and functional neuroanatomyLai, W.-S.; Ramiro, L.-L.R.; Yu, H.A.; Johnston, R.E.; WEN-SUNG LAI Journal of Neuroscience8578
592005Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in micePaterlini, M.; Zakharenko, S.S.; Lai, W.-S.; Qin, J.; Zhang, H.; Mukai, J.; Westphal, K.G.C.; Olivier, B.; Sulzer, D.; Pavlidis, P.; Siegelbaum, S.A.; Karayiorgou, M.; WEN-SUNG LAI Nature Neuroscience215200
602004Patterns of neural activation associated with exposure to odors from a familiar winner in male golden hamstersLai, W.-S.; Chen, A.; Johnston, R.E.; WEN-SUNG LAI Hormones and Behavior1919
612004Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophreniaMukai, J.; Liu, H.; Burt, R.A.; Swor, D.E.; Lai, W.-S.; Karayiorgou, M.; Gogos, J.A.; WEN-SUNG LAI Nature Genetics258249
622002Individual recognition after fighting by golden hamsters: A new methodLai, W.-S.; Johnston, R.E.; WEN-SUNG LAI Physiology and Behavior7774
632002The Role of Catecholamines in Retention Performance of a Partially Baited Radial Eight-Arm Maze for RatsWEN-SUNG LAI The Chinese Journal of Physiology1210