研究成果


第 1 到 25 筆結果，共 25 筆。

公開日期標題作者來源出版物scopusWOS全文
12023TRAF3-EWSR1 signaling axis acts as a checkpoint on germinal center responsesLi, Yanchuan; Zhu, Lele; Chun-Jung Ko ; Yang, Jin-Young; Wang, Hongjiao; Manyam, Ganiraju; Wang, Jing; Cheng, Xuhong; Zhao, Shuli; Jie, ZuliangThe Journal of experimental medicine
22023Correction: TRAF3-EWSR1 signaling axis acts as a checkpoint on germinal center responsesLi, Yanchuan; Zhu, Lele; Chun-Jung Ko ; Yang, Jin-Young; Wang, Hongjiao; Manyam, Ganiraju; Wang, Jing; Cheng, Xuhong; Zhao, Shuli; Jie, ZuliangThe Journal of experimental medicine
32023Role of the E3 ubiquitin ligase Peli1 in regulating antitumor T cell responsesChun-Jung Ko ; Sun, Shao-CongThe Journal of Immunology
42022Dapl1 controls NFATc2 activation to regulate CD8+ T cell exhaustion and responses in chronic infection and cancerZhu, Lele; Zhou, Xiaofei; Gu, Meidi; Kim, Jiseong; Li, Yanchuan; Chun-Jung Ko ; Xie, Xiaoping; Gao, Tianxiao; Cheng, Xuhong; Sun, Shao-CongNature cell biology76
52022Matriptase-2/NR4A3 axis switches TGF-β action toward suppression of prostate cancer cell invasion, tumor growth, and metastasisLin, Hsin-Ying; Chun-Jung Ko ; Lo, Tzu-Yu; Wu, Shang-Ru; Lan, Shao-Wei; Huang, Chen-An; Lin, Yi-Chin; Lin, Hsin-Hsien; Tu, Hsin-Fang; Lee, Cheng-Fan; Hsiao, Pei-Wen; HSIANG-PO HUANG ; MEI-JOU CHEN ; Chang, Kai-Hsiung; MING-SHYUE LEE Oncogene54
62022Myeloid cell TBK1 restricts inflammatory responsesGao, Tianxiao; Liu, Ting; Chun-Jung Ko ; Zhang, Lingyun; Joo, Donghyun; Xie, Xiaoping; Zhu, Lele; Li, Yanchuan; Cheng, Xuhong; Sun, Shao-CongProceedings of the National Academy of Sciences of the United States of America129
72021Afatinib Exerts Immunomodulatory Effects by Targeting the Pyrimidine Biosynthesis Enzyme CADTu, Hsin-Fang; Chun-Jung Ko ; Lee, Ching-Tai; Lee, Cheng-Fan; Lan, Shao-Wei; Lin, Hsin-Hsien; Lin, Hsin-Ying; CHIA-CHI KU ; Lee, Der-Yen; I-CHUN CHEN ; YA-HUI CHUANG ; Del Caño-Ochoa, Francisco; Ramón-Maiques, Santiago; CHAO-CHI HO ; MING-SHYUE LEE ; GEEN-DONG CHANG Cancer research1414
82021The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responsesChun-Jung Ko ; Zhang L.; Jie Z.; Zhu L.; Zhou X.; Xie X.; Gao T.; Yang J.-Y.; Cheng X.; Sun S.-C.EMBO Journal1411
92021DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesisLi Y.; Xie X.; Jie Z.; Zhu L.; Yang J.-Y.; Chun-Jung Ko ; Gao T.; Jain A.; Jung S.Y.; Baran N.; Konopleva M.Y.; Cheng X.; Sun S.-C.Blood1916
102021TRAF2 regulates T cell immunity by maintaining a Tpl2-ERK survival signaling axis in effector and memory CD8 T cellsXie X.; Zhu L.; Jie Z.; Li Y.; Gu M.; Zhou X.; Wang H.; Chang J.-H.; Chun-Jung Ko ; Cheng X.; Sun S.-C.Cellular and Molecular Immunology75
112021Microglia promote autoimmune inflammation via the noncanonical NF-κB pathwayJie Z.; Chun-Jung Ko ; Wang H.; Xie X.; Li Y.; Gu M.; Zhu L.; Yang J.-Y.; Gao T.; Ru W.; Tang S.-J.; Cheng X.; Sun S.-C.Science Advances1818
122021Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitinationZhang L.; Chun-Jung Ko ; Li Y.; Jie Z.; Zhu L.; Zhou X.; Xie X.; Gao T.; Liu T.; Cheng X.; Sun S.-C.Cell Reports1414
132020Intestinal Epithelial TBK1 Prevents Differentiation of T-helper 17 Cells and Tumorigenesis in MiceYang J.-Y.; Jie Z.; Mathews A.; Zhou X.; Li Y.; Gu M.; Xie X.; Chun-Jung Ko ; Cheng X.; Qi Y.; Estrella J.S.; Wang J.; Sun S.-C.Gastroenterology1412
142020Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasisChun-Jung Ko ; Hsu, Ting-Wei; Wu, Shang-Ru; Lan, Shao-Wei; Hsiao, Ting-Feng; Lin, Hsin-Ying; Lin, Hsin-Hsien; Tu, Hsin-Fang; Lee, Cheng-Fan; Huang, Cheng-Chung; Chen, Mei-Ju May; Hsiao, Pei-Wen; HSIANG-PO HUANG ; MING-SHYUE LEE Oncogene2825
152019HAI-2 as a novel inhibitor of plasmin represses lung cancer cell invasion and metastasisWu S.-R.; Lin C.-H.; Shih H.-P.; Chun-Jung Ko ; Lin H.-Y.; Lan S.-W.; Lin H.-H.; Tu H.-F.; CHAO-CHI HO ; HSIANG-PO HUANG ; MING-SHYUE LEE British Journal of Cancer89
162019TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesisZhu L.; Li Y.; Xie X.; Zhou X.; Gu M.; Jie Z.; Chun-Jung Ko ; Gao T.; Hernandez B.E.; Cheng X.; Sun S.-C.Nature Cell Biology4545
172019Activation of sphingosine kinase by lipopolysaccharide promotes prostate cancer cell invasion and metastasis via SphK1/S1PR4/matriptaseLee, Cheng-Fan; Dang, Andrew; Hernandez, Elizabeth; Pong, Rey-Chen; Chen, Benjamin; Sonavane, Rajni; Raj, Ganesh; Kapur, Payal; Lin, Hsin-Ying; Wu, Shang-Ru; Chun-Jung Ko ; Lo, U-Ging; HSIN-YU LEE ; Hsieh, Jer-Tsong; MING-SHYUE LEE Oncogene2729
182017The Kunitz Domain i of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer CellsWu S.-R.; Teng C.-H.; Tu Y.-T.; Chun-Jung Ko ; Cheng T.-S.; Lan S.-W.; Lin H.-Y.; Lin H.-H.; Tu H.-F.; Hsiao P.-W.; HSIANG-PO HUANG ; CHUNG-HSIN CHEN ; MING-SHYUE LEE Scientific Reports1512
192017Inhibition of cyclooxygenase-2-mediated matriptase activation contributes to the suppression of prostate cancer cell motility and metastasisChun-Jung Ko ; Lan S.-W.; YU-CHUAN LU ; Cheng T.-S.; Lai P.-F.; Tsai C.-H.; Hsu T.-W.; Lin H.-Y.; Shyu H.-Y.; Wu S.-R.; Lin H.-H.; Hsiao P.-W.; CHUNG-HSIN CHEN ; HSIANG-PO HUANG ; MING-SHYUE LEE Oncogene3832
202016Ketamine Increases Permeability and Alters Epithelial Phenotype of Renal Distal Tubular Cells via a GSK-3β-Dependent MechanismShyu H.-Y.; Chun-Jung Ko ; Luo Y.-C.; Lin H.-Y.; Wu S.-R.; Lan S.-W.; Cheng T.-S.; Hu S.-H.; MING-SHYUE LEE Journal of Cellular Biochemistry1110
212015Androgen-induced TMPRSS2 activates matriptase and promotes extracellular matrix degradation, prostate cancer cell invasion, tumor growth, and metastasisChun-Jung Ko ; Huang C.-C.; Lin H.-Y.; Juan C.-P.; Lan S.-W.; Shyu H.-Y.; Wu S.-R.; Hsiao P.-W.; HSIANG-PO HUANG ; CHIA-TUNG SHUN ; MING-SHYUE LEE Cancer Research108100
222014Proteomic analysis of osteoarthritic chondrocyte reveals the hyaluronic acid-regulated proteins involved in chondroprotective effect under oxidative stressYu C.-J.; Chun-Jung Ko ; Hsieh C.-H.; Chien C.-T.; Huang L.-H.; Lee C.-W.; Jiang C.-C.Journal of Proteomics5043
232014HAI-2 suppresses the invasive growth and metastasis of prostate cancer through regulation of matriptaseTsai C.-H.; Teng C.-H.; Tu Y.-T.; Cheng T.-S.; Wu S.-R.; Chun-Jung Ko ; Shyu H.-Y.; Lan S.-W.; HSIANG-PO HUANG ; Tzeng S.-F.; Johnson M.D.; Lin C.-Y.; Hsiao P.-W.; MING-SHYUE LEE Oncogene4642
242013Curcumin-targeting pericellular serine protease matriptase role in suppression of prostate cancer cell invasion, tumor growth, and metastasisCheng T.-S.; Chen W.-C.; Lin Y.-Y.; Tsai C.-H.; Liao C.-I.; Shyu H.-Y.; Chun-Jung Ko ; Tzeng S.-F.; Huang C.-Y.; PAN-CHYR YANG ; Hsiao P.-W.; MING-SHYUE LEE Cancer Prevention Research4142
252010Matriptase is involved in ErbB-2-induced prostate cancer cell invasionWu S.-R.; Cheng T.-S.; Chen W.-C.; Shyu H.-Y.; Chun-Jung Ko ; HSIANG-PO HUANG ; Teng C.-H.; Lin C.-H.; Johnson M.D.; Lin C.-Y.; MING-SHYUE LEE American Journal of Pathology3431