https://scholars.lib.ntu.edu.tw/handle/123456789/109074
標題: | Prevalence and determinants of hepatitis B antigenemia in 15,007 prisoners in Taiwan | 作者: | 林慶豐 涂醒哲 陳萍和 鄭若瑟 王榮德 LIN, CHING-FENG TWU, SHIING-JER CHEN, PING-HO CHENG, JOSEPH JROR-SERK WANG, JUNG-DER |
公開日期: | 2010 | 卷: | 20 | 期: | 3 | 起(迄)頁: | 231-236 | 來源出版物: | JOURNAL OF EPIDEMIOLOGY | 摘要: | The goal of this study was to determine the prevalence and risk factors for horizontal transmission of hepatitis B infection due to intravenous drug abuse (IVDA), tattooing, blood transfusion, and combinations of these risk factors. Methods: All people detained in 19 prisons were invited to participate. Subjects underwent a physical examination and completed a questionnaire. Blood samples were collected and screened for hepatitis B surface antigen and Venereal Disease Research Laboratory (VDRL) reactivity. Results: A total of 16 204 prisoners were invited to participate. The response rate was 92.6% and the mean age was 29.73 years. The overall prevalence of HBsAg positivity was 21.7%. Among 3333 subjects with a history of blood transfusion, the carrier rate was 23.19%. Among the 3071 subjects with a history of IVDA and the 6908 subjects with tattoos, the carrier rate was 26.4% and 29.3%, respectively. IVDA appeared to be the strongest risk factor among the 3, with an adjusted odds ratio (AOR) of 1.54 (95% confidence interval, 1.27-1.86), followed by tattooing (1.40. 1.23-1.55 ), and blood transfusion (1.27, 1.05-1.61). When blood transfusion was combined with either of the other 2 risk factors, the risk increased multiplicatively, and the combination of the 3 factors increased the AOR to 2.76 (2.20 -3.47). The prevalence of a positive VDRL test result was 1. 01%. Conclusions: The prevalence of HBV antigenemia in prisoners was high and was associated with BT, IVDA, and tattooing. A national vaccination program against HBV should be considered for prisoners and other people with these risk factors. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/233178 |
顯示於: | 公共衛生學系 |
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