https://scholars.lib.ntu.edu.tw/handle/123456789/110881
標題: | 半導體業潛在砷暴露危害評估-實證資料分析 | 作者: | 黃耀輝 | 關鍵字: | 半導體業;尿中砷濃度;風險推估;蒙地卡羅模擬;semiconductor;urinary arsenic;risk estimation;Monte Carlo simulation | 公開日期: | 31-七月-2002 | 出版社: | 臺北市:國立臺灣大學公共衛生學院職業醫學與工業衛生研究所 | 摘要: | 本研究之目的在於調查晶圓廠機台維 修人員可能砷暴露情形,並推估其潛在砷 暴露作業下可能發生的健康風險值。研究 結果發現,維修保養工程師之尿中總無機 砷代謝產物平均為32.8 ±29.1μg/L,而對 照組則為32.1 ±25.1μg/L 。但比較三名維 修工程師在同一日工作前與下工後的尿中 總無機胂濃度的結果顯示,本研究維修工 作區有明顯的職業性砷暴露。同時,而在 維修工程師之終生癌症風險的推估方面, 以蒙地卡羅模擬的結果,工作五年的平均 終身癌症風險值為3.58 ×10 -5 ,接近一般認 同之可接受的風險值10 -4 ~10 -6 。此外,針 對有無配戴個人防護具來進行維修作業的 模擬分析結果顯示,沒有配戴個人防護具 的情況下會有五倍高的終身致癌風險值。 同時在此模擬模式的敏感度分析結果顯 示,敏感度最高的參數依次是尿中砷濃度值、暴露頻率,以及體重。 The aims of this study is to investigate the possible arsenic exposure among the maintenance engineers of wafer fabrication facilities, in order to predict the potential health risk after long-term occupational exposure to arsenic. For urinary arsenic level, average urinary arsenic levels of control group and maintenance engineers were 32.1±25.7 μ g/L and 32.8±29.1 μ g/L, respectively. However, by comparing the urine arsenic concentrations before and after workshift of three preventative maintenance engineers, occupationally exposure to arsenic is strongly suggested in the study site. Meanwhile, the average of Incremental Lifetime Cancer Risk of the maintenance engineers for working 5 years was 3.58×10 -5 , within the universally acceptable level of 10 -6 ~10 -4 . Besides, the simulation results of life cancer risk for those engineers not wearing personal protective equipment at work were nearly five times the risk for these wearing. The sensitivity analysis indicated that the input variables which are more sensitive in the risk estimation for preventative maintenance engineers exposure to arsenic are concentration of urinary arsenic, exposure frequency, and body weight. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/4957 | 其他識別: | 902320B002179 | Rights: | 國立臺灣大學公共衛生學院職業醫學與工業衛生研究所 |
顯示於: | 環境與職業健康科學研究所 |
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902320B002179.pdf | 163.39 kB | Adobe PDF | 檢視/開啟 |
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