Frequency of Prescribing Chinese Herb Medicine May Containing Plant Species of the Genus Aristolochia in National Health Insurance in Taiwan Between 1997-2001
|Keywords:||馬兜鈴酸;腎毒性;中草藥;全民健保;細辛;Aristolochic acid;Nephrotoxicity;Chinese herb medicine;National Health Insurance;Si-Sin||Issue Date:||2006||Abstract:||
Object：This study was conducted to determine the current prescription patterns of Chinese Herb Medicine May Containing Plant Species of the Genus Aristolochia in National Health Insurance in Taiwan between 1997-2001. and explore the different of prescription patterns between Taiwan’s regular using and Belgian’s Chinese herbs nephropathy cases. Method：The database containing 200,000 people randomly sampled from the National Health Insurance (NHI) system during 1997-2001 was used. The retrospective cohort was stratified for age, gender, cumulative prescribing days of mixtures containing Si-sin、Fang-ji、Mu-tong、Mu-siang、tian-sian-teng and Ma-dou-ling. Result：103630 people used Chinese medicine service and had 5098390 prescriptions between 1997-2001. There were 64216 people taking 361333 prescriptions containing these six kinds of drug, with a mean prescribing age of 37.9±19.3 and 76964 prescriptions between 35-44 years old. Using incidence rate of hole people is 64.2*10-3Year-1.Female gender is more than male. The mixture contain Si-Sin is the highest. All other kinds of mixtures had the most popular age range between 35-44 expecting Si-sin is under the 15 years old. 5999 prescriptions of six kinds of mixture had individual prescribing day more than eight days. The mean age of first time taking prescription of seven mixtures are 34.9±18.8 years old; all had the most popular age range between 35-44 expecting Si-sin is under the 15 and tian-sian-teng is between 25-34 years old. The cumulative prescribing day of all seven kinds of mixture is 32.9±56.1 days; 46355 people were less than 30 days. 5089 people had cumulative prescribing day more than 3 months. Conclusion：In Taiwan, the Chinese Herb Containing Plant Species of the Genus Aristolochia is no more used expect Si-sin. Our study find the using of mixture contain Si-sin is popular. Although the cumulative prescribing day is not as long as Belgian’s cases, Sin-Sin is frequently used in children under 15 years old. They may have lower danger dose than adult and has much long life time for cumulative dose. It is very crucial to further clarify the effect of Si-Sin on kidney function and urinary cancer in the future.
|Appears in Collections:||環境與職業健康科學研究所|
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