DC 欄位 | 值 | 語言 |
dc.contributor | 臺大公衛學院-流行病學與預防醫學研究所; | en |
dc.contributor.author | Pan, Hsueh-Hsing | en |
dc.contributor.author | Li, Chung-Yi | en |
dc.contributor.author | Chen, Pei-Chun | en |
dc.contributor.author | Lee, Ming-Der | en |
dc.contributor.author | Liang, Chun-Yu | en |
dc.contributor.author | Hou, Wen-Hsuan | en |
dc.contributor.author | Wang, Kwua-Yun | en |
dc.creator | Pan, Hsueh-Hsing;Li, Chung-Yi;Chen, Pei-Chun;Lee, Ming-Der;Liang, Chun-Yu;Hou, Wen-Hsuan;Wang, Kwua-Yun | en |
dc.creator | 陳培君 | zh-tw |
dc.date | 2012 | en |
dc.date.accessioned | 2014-02-17T09:20:13Z | - |
dc.date.accessioned | 2018-06-29T18:34:39Z | - |
dc.date.available | 2014-02-17T09:20:13Z | - |
dc.date.available | 2018-06-29T18:34:39Z | - |
dc.date.issued | 2012 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/259987 | - |
dc.description.abstract | Objective: To prospectively examine the roles of diabetic macro-vascular complications and hip fracture in association with depression onset in Taiwan's elderly diabetic population.
Methods: A representative sample of elderly diabetic patients (n=144,216) identified in 2000 were linked to National Health Insurance claims (2000-2007) to ascertain the diagnoses of depression in both outpatient and inpatient settings. The person-year approach with Poisson assumption was used to estimate the hazard rates. Using Cox proportional hazard regression model, we evaluated the relative risk of depression in relation to diabetic macro-vascular complications and hip fracture. The additive effects from the above medical conditions were also assessed.
Results: The 8-year cumulative risk of depression was 5.08%, representing an incidence density of 8.40 per 1000 patient-years. Hazard ratio (HR) with 95% confidence interval (Cl) for the elderly diabetes associated with cardiovascular disease (CVD), hip fracture, and lower extremity amputation was 1.13 (1.04-1.23), 1.10(0.91-1.34), and 1.25 (0.95-1.65), respectively. Additionally, we found that the more the complications or hip fracture, the higher the risk of depression onset in elderly diabetes.
Conclusion: The increased number of diabetic macro-vascular complications and hip fracture is significantly associated with a higher risk of depression onset in elderly diabetes. Future studies should be conducted to assess the feasibility and cost-effectiveness of intensive depression screening program in elderly diabetes suffering from macro-vascular complications and hip fracture. (C) 2012 Elsevier Inc. All rights reserved. | en |
dc.format.extent | 114 bytes | - |
dc.format.mimetype | text/html | - |
dc.language | en-us | en |
dc.relation | J. Psychosomat. Res., 73(3), 180-184 | en |
dc.relation.ispartof | Journal of Psychosomatic Research | en_US |
dc.subject | Depression | en |
dc.subject | Diabetic complications | en |
dc.subject | Elderly | en |
dc.subject | Population-based | en |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | aged; article; cohort analysis; depression; diabetic angiopathy; disease association; female; follow up; hazard ratio; hip fracture; human; incidence; major clinical study; male; non insulin dependent diabetes mellitus; population research; prospective study; risk assessment; risk factor; Age Factors; Aged; Cardiovascular Diseases; Depressive Disorder; Diabetic Angiopathies; Female; Follow-Up Studies; Hip Fractures; Humans; Male; Poisson Distribution; Proportional Hazards Models; Prospective Studies; Risk; Sex Factors; Taiwan | - |
dc.title | Contributions of diabetic macro-vascular complications and hip fracture to depression onset in elderly patients with diabetes: An 8-year population-based follow-up study | en |
dc.identifier.doi | 10.1016/j.jpsychores.2012.06.003 | en |
dc.relation.pages | 180-184 | - |
dc.identifier.uri.fulltext | http://ntur.lib.ntu.edu.tw/bitstream/246246/259987/1/index.html | - |
item.grantfulltext | open | - |
item.fulltext | with fulltext | - |
顯示於: | 流行病學與預防醫學研究所
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