https://scholars.lib.ntu.edu.tw/handle/123456789/114116
標題: | Cardiovascular Disease and Colorectal Cancer: A Population-Based Observation in Taiwan | 作者: | Lai, Shih-Wei Liao, Kuan-Fu Lai, Hsueh-Chou Tsai, Pang-Yao Sung, Fung-Chang Chen, Pei-Chun |
關鍵字: | cardiovascular disease;colorectal adenoma;colorectal cancer | 公開日期: | 2013 | 卷: | 45 | 期: | 1 | 起(迄)頁: | 31-36 | 來源出版物: | Kuwait Med. J. | 摘要: | Objective: To explore the relationship between cardiovascular disease and colorectal cancer in Taiwan Design: Population-based cohort study Subjects: Using database of the Taiwan National Health Insurance program from 2000 to 2006, 89,034 patients (35 years or older) with newly diagnosed cardiovascular disease (CVD) which included coronary artery disease, heart failure, cerebrovascular disease, peripheral atherosclerosis, or hypertension, and 89,034 control subjects without CVD were studied Main Outcome Measures: The incidence of colorectal cancer at the end of 2009 and the association with CVD and other co-morbidities were determined Results: The incidence of colorectal cancer was 1.19-fold higher in the CVD group compared with the non-CVD group (10.87 Vs 9.11 per 10,000 person-years, 95% CI = 1.051.36). After adjustment for covariates, no association was found between CVD and colorectal cancer (95% CI = 0.87-1.13). Men (HR = 1.53, 95% CI = 1.34-1.75), increasing age (HR = 1.07, 95% CI = 1.06-1.07), and colorectal adenoma (HR = 1.80, 95% CI = 1.06-3.05) were associated with colorectal cancer. Conclusions: No association between cardiovascular disease and colorectal cancer is found. Men, increasing age, and colorectal adenoma correlate with the increased risk of colorectal cancer. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/260019 |
顯示於: | 流行病學與預防醫學研究所 |
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