|Title:||Cardiovascular Disease and Colorectal Cancer: A Population-Based Observation in Taiwan||Authors:||Lai, Shih-Wei
|Keywords:||cardiovascular disease;colorectal adenoma;colorectal cancer||Issue Date:||2013||Journal Volume:||45||Journal Issue:||1||Start page/Pages:||31-36||Source:||Kuwait Med. J.||Abstract:||
Objective: To explore the relationship between cardiovascular disease and colorectal cancer in Taiwan
Design: Population-based cohort study
Subjects: Using database of the Taiwan National Health Insurance program from 2000 to 2006, 89,034 patients (35 years or older) with newly diagnosed cardiovascular disease (CVD) which included coronary artery disease, heart failure, cerebrovascular disease, peripheral atherosclerosis, or hypertension, and 89,034 control subjects without CVD were studied
Main Outcome Measures: The incidence of colorectal cancer at the end of 2009 and the association with CVD and other co-morbidities were determined
Results: The incidence of colorectal cancer was 1.19-fold higher in the CVD group compared with the non-CVD group (10.87 Vs 9.11 per 10,000 person-years, 95% CI = 1.051.36). After adjustment for covariates, no association was found between CVD and colorectal cancer (95% CI = 0.87-1.13). Men (HR = 1.53, 95% CI = 1.34-1.75), increasing age (HR = 1.07, 95% CI = 1.06-1.07), and colorectal adenoma (HR = 1.80, 95% CI = 1.06-3.05) were associated with colorectal cancer.
Conclusions: No association between cardiovascular disease and colorectal cancer is found. Men, increasing age, and colorectal adenoma correlate with the increased risk of colorectal cancer.
|Appears in Collections:||流行病學與預防醫學研究所|
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