https://scholars.lib.ntu.edu.tw/handle/123456789/136471
標題: | GeneNetwork: an interactive tool for reconstruction of genetic networks using microarray data | 作者: | Wu, Chia-Chin Huang, Hsuan-Cheng Juan, Hsueh-Fen Chen, Shui-Tein |
公開日期: | 2004 | 卷: | 20 | 期: | 18 | 起(迄)頁: | 3691-3693 | 來源出版物: | Bioinformatics | 摘要: | Summary: Inferring genetic network architecture from time series data generated from high-throughput experimental technologies, such as cDNA microarray, can help us to understand the system behavior of living organisms. We have developed an interactive tool, GeneNetwork, which provides four reverse engineering models and three data interpolation approaches to infer relationships between genes. GeneNetwork enables a user to readily reconstruct genetic networks based on microarray data without having intimate knowledge of the mathematical models. A simple graphical user interface enables rapid, intuitive mapping and analysis of the reconstructed network allowing biologists to explore gene relationships at the system level. © Oxford University Press 2004; all rights reserved. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/161531 https://www.scopus.com/inward/record.uri?eid=2-s2.0-12344257752&doi=10.1093%2fbioinformatics%2fbth428&partnerID=40&md5=86d8f588c69c0bcf840f6970491130ed |
ISSN: | 13674803 | DOI: | 10.1093/bioinformatics/bth428 | SDG/關鍵字: | article; computer program; data analysis; DNA microarray; gene mapping; gene technology; genetic analysis; genetic association; genetic engineering; high throughput screening; information processing; mathematical model; priority journal; process model; time series analysis; Algorithms; Computer Graphics; Computer Simulation; Gene Expression Profiling; Models, Genetic; Numerical Analysis, Computer-Assisted; Oligonucleotide Array Sequence Analysis; Signal Transduction; Software; User-Computer Interface |
顯示於: | 生命科學系 |
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