https://scholars.lib.ntu.edu.tw/handle/123456789/145264
標題: | A case-control study of chronic prostatitis/chronic pelvic pain syndrome and colorectal cancer | 作者: | Chung, Shiu-Dong Keller, Joseph J. Lin, Herng-Ching |
關鍵字: | colorectal cancer;chronic prostatitis;chronic pelvic pain syndrome | 公開日期: | 2012 | 卷: | 110 | 期: | 4 | 起(迄)頁: | 550-554 | 來源出版物: | BJU Int. | 摘要: | OBJECTIVE ;To estimate the association between chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and colorectal cancer (CRC) using a nationwide population-based data set. ;PATIENTS AND METHODS ;This case-control study used data sourced from the Taiwan Longitudinal Health Insurance Database. ;The cases comprised 2899 patients with CRC and 14 995 randomly selected subjects as controls. ;We used conditional logistic regression to examine the association between CRC and previous diagnosis of CP/CPPS. ;RESULTS ;Of the sampled patients, 531(3.05%) had been diagnosed with CP/CPPS before the index date, with 123 (4.24% of the patients with CRC) coming from the cases and 408 individuals (2.81% of patients without CRC) coming from the controls. ;Conditional logistic regression analysis revealed that cases were more likely to have CP/CPPS than controls (odds ratio 1.45, 95% CI 1.17-1.79, P < 0.001) after adjusting for the monthly income, geographic location, urbanization level, hypertension, diabetes, renal disease, obesity and cystic kidney disease. ;In subgroup analysis, we found the magnitude of the association to be higher in subjects younger than 60 years (age 40-49, odds ratio 2.01; 95% CI 2.04-3.58 and aged 50-59, 2.40, 95% CI 1.48-3.87, both P < 0.001) than among other age groups. ;CONCLUSION ;We conclude that CP/CPPS patients are at higher risk for CRC, especially in males under 60 years of age. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/279484 | DOI: | 10.1111/j.1464-410X.2012.10929.x | SDG/關鍵字: | adult; age; aged; article; cancer risk; chronic prostatitis; colorectal cancer; controlled study; demography; diabetes mellitus; disease association; human; hypertension; income; kidney disease; kidney polycystic disease; major clinical study; male; obesity; pelvis pain syndrome; population based case control study; priority journal; random sample; retrospective study; Taiwan; urbanization; Adult; Aged; Case-Control Studies; Chronic Disease; Colorectal Neoplasms; Humans; Male; Middle Aged; Odds Ratio; Pelvic Pain; Prevalence; Prostatitis; Retrospective Studies; Taiwan |
顯示於: | 臨床醫學研究所 |
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