https://scholars.lib.ntu.edu.tw/handle/123456789/146418
標題: | Association of Single-Nucleotide Polymorphism 3 and C.553g > T of Apoa5 with Hypertriglyceridemia after Treatment with Highly Active Antiretroviral Therapy Containing Protease Inhibitors in Hiv-Infected Individuals in Taiwan | 作者: | CHANG, SUI-YUAN KO, WEI-SHIN KAO, JAU-TSUEN LEE, CHUN-NAN SUN, HSIN-YUN CHEN, MAO-YUAN HSIEH, SZU-MIN SHENG, WANG-HUEI CHANG, SHU-FANG LIU, WEN-CHUN WU, CHENG-HSIN CHANG, SHAN-CHWEN KAO, CHUAN-LIANG HUNG, CHIEN-CHING |
公開日期: | 2009 | 卷: | v.48 | 期: | n.6 | 起(迄)頁: | 832-835 | 來源出版物: | CLINICAL INFECTIOUS DISEASES | 摘要: | We investigated the relationship between hypertriglyceridemia and the single-nucleotide polymorphisms (SNPs) on APOA5 in human immunodeficiency virus (HIV)- infected patients receiving highly active antiretroviral therapy (HAART) in Taiwan. Receipt of protease inhibitor- based HAART, high baseline triglyceride levels, and carriage of APOA5 SNP3 or c.553G>T variants or APOA5 SNP1T/SNP2G/SNP 3C/c.553T haplotype were statistically significantly associated with development of extreme hypertriglyceridemia( triglyceride level, >500 mg/dL) |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/188808 |
顯示於: | 醫學檢驗暨生物技術學系 |
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