https://scholars.lib.ntu.edu.tw/handle/123456789/158171
標題: | The suppressive effect of electrical stimulation on nociceptive responses in the rat | 作者: | WANG, SHWU-FEN CHEN, YANG-WEN SHYU, BAI-CHUANG 王淑芬 |
公開日期: | 1997 | 卷: | v.77 | 期: | n.8 | 起(迄)頁: | 839-847 | 來源出版物: | PHYSICAL THERAPY | 摘要: | Background and Purpose: The aim of this investigation was to study the effect of electrical stimulation on nociceptive responses within the lumbar levels of the rat spinal cord. Methods: A single high-energy thermal pulse produced by a surgical laser stimulator (5W, 30 milliseconds ) was applied on the plantar surface of the hind paws of male Sprague- Dawley rats. The spinal cord field potential evoked by the laser pulse was used as an indicator of thermosensitive nociceptive responses. Low- intensity single stimulation, high-intensity single stimulation, low- intensity train stimulation, and high-intensity train stimulation were applied on the common peroneal nerve with protected cuff electrodes in different trials. Results: Neither low- intensity nor high- intensity single stimulation suppressed field potentials. Furthermore, high- intensity train stimulation elicited biphasic inhibition at a wider range of intervals lasting for 20 seconds. Conclusion and Discussion : The results demonstrate that two models of train electrical stimulation can produce two patterns of fast- onset (within milliseconds), short-duration (within 20 seconds) inhibition of field potentials in the spinal cord. These results provide evidence that noxious heat-related impulses are modulated by the presence of specific electrical stimulation. The clinical application of transcutaneous electrical nerve stimulation to block pain is supported. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/96981 |
顯示於: | 物理治療學系所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。