|Title:||Rare Presentation of Endocrine Pancreatic Tumor: A Case of Diffuse Glucagonoma without Metastasis and Necrolytic Migratory Erythema||Authors:||CHEN, HUAN-WU
SU, DENG- HUANG
|Keywords:||adenoma;islet cel;glucagonoma;signs and symptoms||Issue Date:||2005||Journal Volume:||v.104||Journal Issue:||n.5||Start page/Pages:||363-366||Source:||JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION||Abstract:||
Glucagonoma is a very rare endocrine pancreatic tumor. At diagnosis, most glucagonomas are and often metastatic. Suspicion of glucagonoma is based on characteristic presentations known as syndrome". Glucagonoma is often found in the pancreatic body and/or tail and is usually large enough to localized by computed tomography. We report a case of diffuse glucagonoma necrolytic migratory erythema (NME) in a 45-year-old man with mild diabetes mellitus, mild anemia, and weight loss over 1.5 years. Diffused pancreas was noted on abdominal ultrasonography incidentally during a routine health check-up. The levels carcinoembryonic antigen and carbohydrate antigen 19-9 were within normal limits. No enlarged lymph node extrapancreatic tumor mass was found by several imaging studies. Total pancreatectomy was performed, and pathology revealed glucagon- producing islet cells and intrapancreatic vascular emboli of tumor cells. He died to internal bleeding and sepsis after surgery . Presentation of diffuse malignant glucagonoma with tumor emboli no metastasis or NME is unusual.
|Appears in Collections:||法醫學科所|
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