|Title:||Ethnic Differences in Cardiovascular Risks and Mortality in Atherothrombotic Disease: Insights from the Reduction of Atherothrombosis for Continued Health (Reach) Registry||Authors:||Meadows, Telly A.
Bhatt, Deepak L.
Cannon, Christopher P.
Gersh, Bernard J.
Wilson, Peter W.F.
Smith, Sidney C.
Steg, Ph. Gabriel
|Issue Date:||2011||Start page/Pages:||960-967||Source:||Mayo Clinic Proceedings||Abstract:||
OBJECTIVE: To determine whether ethnic-specific differences in the prevalence of cardiovascular risk factors and outcomes exist worldwide among individuals with stable arterial disease. PATIENTS AND METHODS: From December 1, 2003, to June 30, 2004, the prospective, observational REduction of Atherothrombosis for Continued Health (REACH) Registry enrolled 49,602 outpatients with coronary artery disease, cerebrovascular disease, and/or peripheral arterial disease from 7 predefined ethnic/ racial groups: white, Hispanic, East Asian, South Asian, Other Asian, black, and Other (comprising any race distinct from those specified). The baseline demographic and risk factor profiles, medication use, and 2-year cardiovascular outcomes were assessed among these groups. RESULTS: The prevalence of traditional atherothrombotic risk factors varied significantly among the ethnic/racial groups. The use of medical therapies to reduce risk was comparable among all groups. At 2-year follow-up, the rate of cardiovascular death was significantly higher in blacks (6.1%) compared with all other ethnic/racial groups (3.9%; P=.01). Cardiovascular death rates were significantly lower in all 3 Asian ethnic/racial groups (overall, 2.1%) compared with the other groups (4.5%; P <.001). CONCLUSION : The REACH Registry, a large international study of individuals with atherothrombotic disease, documents the important ethnic- specific differences In cardiovascular risk factors and variations in cardiovascular mortality that currently exist worldwide.
|Appears in Collections:||醫學系|
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