https://scholars.lib.ntu.edu.tw/handle/123456789/189794
標題: | Ethnic Differences in Cardiovascular Risks and Mortality in Atherothrombotic Disease: Insights from the Reduction of Atherothrombosis for Continued Health (Reach) Registry | 作者: | Meadows, Telly A. Bhatt, Deepak L. Cannon, Christopher P. Gersh, Bernard J. Röther, Joachim Goto, Shinya Liau, Chiau-Suong Wilson, Peter W.F. Salette, Genevieve Smith, Sidney C. Steg, Ph. Gabriel |
公開日期: | 2011 | 起(迄)頁: | 960-967 | 來源出版物: | Mayo Clinic Proceedings | 摘要: | OBJECTIVE: To determine whether ethnic-specific differences in the prevalence of cardiovascular risk factors and outcomes exist worldwide among individuals with stable arterial disease. PATIENTS AND METHODS: From December 1, 2003, to June 30, 2004, the prospective, observational REduction of Atherothrombosis for Continued Health (REACH) Registry enrolled 49,602 outpatients with coronary artery disease, cerebrovascular disease, and/or peripheral arterial disease from 7 predefined ethnic/ racial groups: white, Hispanic, East Asian, South Asian, Other Asian, black, and Other (comprising any race distinct from those specified). The baseline demographic and risk factor profiles, medication use, and 2-year cardiovascular outcomes were assessed among these groups. RESULTS: The prevalence of traditional atherothrombotic risk factors varied significantly among the ethnic/racial groups. The use of medical therapies to reduce risk was comparable among all groups. At 2-year follow-up, the rate of cardiovascular death was significantly higher in blacks (6.1%) compared with all other ethnic/racial groups (3.9%; P=.01). Cardiovascular death rates were significantly lower in all 3 Asian ethnic/racial groups (overall, 2.1%) compared with the other groups (4.5%; P <.001). CONCLUSION : The REACH Registry, a large international study of individuals with atherothrombotic disease, documents the important ethnic- specific differences In cardiovascular risk factors and variations in cardiovascular mortality that currently exist worldwide. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/240761 | DOI: | 10.4065/mcp.2011.0010 | SDG/關鍵字: | 2,4 thiazolidinedione derivative; acetylsalicylic acid; angiotensin receptor antagonist; beta adrenergic receptor blocking agent; biguanide derivative; calcium channel blocking agent; dipeptidyl carboxypeptidase inhibitor; diuretic agent; hydroxymethylglutaryl coenzyme A reductase inhibitor; insulin; nitrate; nonsteroid antiinflammatory agent; sulfonylurea; adult; aged; article; Asian; body mass; cardiovascular risk; Caucasian; cerebrovascular disease; cigarette smoking; controlled study; coronary artery disease; demography; diabetes mellitus; drug use; employment status; ethnic difference; female; follow up; Hispanic; human; hyperlipidemia; hypertension; major clinical study; male; mortality; Negro; peripheral occlusive artery disease; prospective study; risk assessment; risk reduction |
顯示於: | 醫學系 |
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