DC 欄位 | 值 | 語言 |
dc.contributor | 臺大醫院-內科部;臺大醫學院; | en |
dc.contributor.author | Yang J.-Y. | en_US |
dc.contributor.author | TSUNG-CHUN LEE | en_US |
dc.contributor.author | Montez-Rath M.E. | en_US |
dc.contributor.author | Chertow G.M. | en_US |
dc.contributor.author | Winkelmayer W.C. | en_US |
dc.creator | Yang, Ju-Yeh;Lee, Tsung-Chun;Montez-Rath, Maria E.;Chertow, Glenn M.;Winkelmayer, Wolfgang C. | en |
dc.creator | 李宗錞 | zh-tw |
dc.date | 2013 | en |
dc.date.accessioned | 2014-02-14T06:45:49Z | - |
dc.date.accessioned | 2018-07-11T07:03:11Z | - |
dc.date.available | 2014-02-14T06:45:49Z | - |
dc.date.available | 2018-07-11T07:03:11Z | - |
dc.date.issued | 2013 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/259301 | - |
dc.description.abstract | Background: Impaired kidney function is an established predictor of mortality after acute nonvariceal upper gastrointestinal bleeding (ANVUGIB); however, which factors are associated with mortality after ANVUGIB among patients undergoing dialysis is unknown. We examined the associations among demographic characteristics, dialysis-specific features, and comorbid conditions with short-term mortality after ANVUGIB among patients on dialysis.
Methods: Design: Retrospective cohort study. Setting: United States Renal Data System (USRDS), a nation-wide registry of patients with end-stage renal disease. Participants: All ANVUGIB episodes identified by validated algorithms in Medicare-covered patients between 2003 and 2007. Measurements: Demographic characteristics and comorbid conditions from 1 year of billing claims prior to each bleeding event. We used logistic regression extended with generalized estimating equations methods to model the associations among risk factors and 30-day mortality following ANVUGIB events.
Results: From 2003 to 2007, we identified 40,016 eligible patients with 50,497 episodes of ANVUGIB. Overall 30-day mortality was 10.7% (95% CI: 10.4-11.0). Older age, white race, longer dialysis vintage, peritoneal dialysis (vs. hemodialysis), and hospitalized (vs. outpatient) episodes were independently associated with a higher risk of 30-day mortality. Most but not all comorbid conditions were associated with death after ANVUGIB. The joint ability of all factors captured to discriminate mortality was modest (c=0.68).
Conclusions: We identified a profile of risk factors for 30-day mortality after ANVUGIB among patients on dialysis that was distinct from what had been reported in non-dialysis populations. Specifically, peritoneal dialysis and more years since initiation of dialysis were independently associated with short-term death after ANVUGIB. | en_US |
dc.format.extent | 105 bytes | - |
dc.format.mimetype | text/html | - |
dc.language | en-us | en |
dc.relation | BMC Nephrol., 14 | en_US |
dc.relation.ispartof | BMC Nephrology | en_US |
dc.subject | Gastrointestinal hemorrhage | en_US |
dc.subject | Risk factors | en_US |
dc.subject | Mortality | en_US |
dc.subject | Dialysis | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | acute nonvariceal upper gastrointestinal bleeding; adult; aged; article; comorbidity; female; hemodialysis; hospitalization; human; kidney failure; major clinical study; male; medicare; mortality; peritoneal dialysis; renal replacement therapy; retrospective study; risk factor; upper gastrointestinal bleeding; Acute Disease; Adolescent; Adult; Aged; Cohort Studies; Female; Gastrointestinal Hemorrhage; Humans; Male; Middle Aged; Population Surveillance; Registries; Renal Dialysis; Retrospective Studies; Risk Factors; Time Factors; Young Adult | - |
dc.title | Risk factors of short-term mortality after acute nonvariceal upper gastrointestinal bleeding in patients on dialysis: a population-based study | en_US |
dc.identifier.doi | 10.1186/1471-2369-14-97 | - |
dc.relation.pages | 97 | en_US |
dc.identifier.uri.fulltext | http://ntur.lib.ntu.edu.tw/bitstream/246246/259301/1/index.html | - |
item.fulltext | with fulltext | - |
item.grantfulltext | open | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0002-8352-3266 | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系
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