DC 欄位 | 值 | 語言 |
dc.contributor | 臺大公衛學院-職醫與工衛所;臺大醫院;臺大醫院-內科部;臺大醫院新竹分院;臺大醫學院-內科; | en |
dc.contributor.author | MIN-TSUN LIAO | en_US |
dc.contributor.author | LIAN-YU LIN | en_US |
dc.contributor.author | YAO-HSU YANG | en_US |
dc.contributor.author | TING TSE LIN | en_US |
dc.contributor.author | JIUNN-LEE LIN | en_US |
dc.contributor.author | PAU-CHUNG CHEN | en_US |
dc.contributor.author | CHIA-TI TSAI | en_US |
dc.creator | Liao, Min-Tsun;Lin, Lian-Yu;Yang, Yao-Hsu;Lin, Tin-Tse;Lin, Jiunn-Lee;Chen, Pau-Chung;Tsai, Chia-Ti | en |
dc.creator | 林亮宇 ;陳保中 ;林俊立 ;蔡佳醍 | zh-tw |
dc.date | 2013 | en |
dc.date.accessioned | 2014-02-14T08:55:54Z | - |
dc.date.accessioned | 2018-07-11T07:07:39Z | - |
dc.date.available | 2014-02-14T08:55:54Z | - |
dc.date.available | 2018-07-11T07:07:39Z | - |
dc.date.issued | 2013-07 | - |
dc.identifier.issn | 10116842 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/259658 | - |
dc.identifier.uri | https://www.scopus.com/record/display.uri?eid=2-s2.0-84880635288&origin=inward&txGid=5b4720c8a9636840eee961bc8464d106 | - |
dc.description.abstract | Purpose: Atrial fibrillation (AF) is associated with increased risk of thromboembolisnn, and is also a predisposing factor to dementia. Our investigation was a retrospective observational study to evaluate whether the usage of angiotensin-converting-enzyme inhibitor (ACE) or angiotensin II receptor blocker (ARB) could reduce the incidence of dementia in patients with AF.
Methods: A total of 5221 patients over 20 years of age who had a history of AF as noted in ambulatory and inpatient claims data were enrolled from the National Health Insurance Research Database of Taiwan in 1997 and 1998. Patients with ACEI or ARB were designated as group 1 (4343 patients), and patients without ACEI or ARB were designated as group 2 (878 patients).
Results: During a follow-up of 5.90 +/- 3.39 years, 135 patients of group 1(3.1%) and 25 of group 2(2.8%) developed new-onset dementia. Group 1 and group 2 had similar proportions of new-onset dementia (p = 0.75). The Kaplan-Meier curve demonstrated that patients with ACEI or ARB were not associated with a lower incidence of dementia during the follow-up period (log rank p = 0.91). Cox-regression analysis also showed that usage of ACEI or ARB was not associated with a lower risk of new-onset dementia after adjustment for gender and comorbidities. (Hazard ratio = 0.942, 95% confidence interval 0.589 similar to 1.506, and p = 0.80).
Conclusions: ACEI or ARB may be ineffective in reducing the incidence of dementia in patients with AF. | en_US |
dc.format.extent | 82 bytes | - |
dc.format.mimetype | text/html | - |
dc.language | en-us | en |
dc.language.iso | en | en_US |
dc.relation | Acta Cardiol. Sin., 29(4), 323-327 | en_US |
dc.relation.ispartof | Acta Cardiol. Sin. | en_US |
dc.subject | Angiotensin-converting-enzyme inhibitor | en_US |
dc.subject | Angiotensin II receptor blocker | en_US |
dc.subject | Atrial fibrillation | en_US |
dc.subject | Dementia | en_US |
dc.title | ACEI and ARB did not Reduce the Incidence of Dementia in Patients with Atrial Fibrillation: A Nationwide Cohort Study | en_US |
dc.type | journal article | en |
dc.relation.pages | 323 | en_US |
dc.relation.journalvolume | 29 | en_US |
dc.relation.journalissue | 4 | en_US |
dc.identifier.uri.fulltext | http://ntur.lib.ntu.edu.tw/bitstream/246246/259658/1/index.html | - |
dc.relation.pageend | 327 | en_US |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.fulltext | with fulltext | - |
item.grantfulltext | open | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Master's Program in Smart Medicine and Health Informatics (SMARTMHI) | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUHHC | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Institute of Environmental and Occupational Health Sciences | - |
crisitem.author.dept | Environmental and Occupational Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0002-6283-6554 | - |
crisitem.author.orcid | 0000-0001-7505-6429 | - |
crisitem.author.orcid | 0000-0002-6266-9864 | - |
crisitem.author.orcid | 0000-0002-8810-5127 | - |
crisitem.author.orcid | 0000-0003-2148-3956 | - |
crisitem.author.orcid | 0000-0002-6242-5974 | - |
crisitem.author.orcid | 0000-0002-4853-8665 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | International College | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系
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