https://scholars.lib.ntu.edu.tw/handle/123456789/191821
標題: | The Changes of Serum and Urinary Neopterin Concentritions in Rats after Partial Hepatectomy | 作者: | LAI, HONG-SHIEE | 公開日期: | 1999 | 卷: | v.165 | 期: | n.6 | 起(迄)頁: | 604-608 | 來源出版物: | THE EUROPEAN JOURNAL OF SURGERY | 摘要: | Objective: To investigate the changes in serum and urinary neopterin concentrations over time after partial hepatectomy in rats, and to find out if neopterin can be used as a marker of immunological response during the regulation of liver regeneration. Design: Randomised experiment. Setting: University hospital, Taiwan, R.O.C. Subjects: 84 male Wistar rats weighing about 200g. Interventions: Partial hepatectomy (67%) or sham operation (n = 42 in each group). Main outcome measures: Serum and urinary neopterin concentrations measured by radioimmunoassay preoperatively and on days 1, 2, 3, 5, 7, and 10 postoperatively. Results: Serum neopterin concentrations increased and reached their peak on days 5 and 7 after partial hepatectomy. The urinary neopterin concentration showed a similar trend, but with a more pronounced increase on days 5 and 7. Conclusions: Serum and urinary neopterin concentrations can be used as markers of activated cell-mediated immunity in rats after partial hepatectomy. [ABSTRACT FROM AUTHOR] Copyright of European Journal of Surgery is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts) |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/91384 |
顯示於: | 醫學系 |
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