https://scholars.lib.ntu.edu.tw/handle/123456789/192226
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 外科 | en |
dc.contributor.author | LEE, PO-HUANG | en |
dc.creator | 李伯皇 | zh-tw |
dc.creator | LEE, PO-HUANG | en |
dc.date | 2002 | en |
dc.date.accessioned | 2008-12-16T01:04:23Z | - |
dc.date.accessioned | 2018-07-11T09:25:51Z | - |
dc.date.available | 2008-12-16T01:04:23Z | - |
dc.date.available | 2018-07-11T09:25:51Z | - |
dc.date.issued | 2002 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/91938 | - |
dc.description.abstract | Background. Recent studies show that almost all patients who have rejected a kidney transplant had human leukocyte antigen (HIA) antibodies. In this study, we sought to determine whether patients develop HIA antibodies before chronic rejection. Methods. For the past 8 years, 139 patients who had undergone kidney transplantation were systematically examined, using an enzyme-linked immunosorbent assay-based method, for the development of class-I and class-II HLA antibodies 3 months, 6 months, and yearly after transplantation. Chronic rejection was diagnosed by biopsy. Results. Among 29 patients with chronic rejection, 100% of the patients had HLA antibodies before rejection. Of these patients, 14 patients developed antibodies de novo. In contrast, among 110 patients with stable function, 27% of the patients developed HLA antibodies posttransplant (P<0.001). Conclusions. HLA antibodies were found in 29 consecutive cases of chronic rejection failures as much as one year before the loss of grafts. We conclude that HLA antibodies may be a prerequisite for chronic immunologic rejection. | en |
dc.language | en-us | en |
dc.language.iso | en_US | - |
dc.relation | TRANSPLANTATION v.74 n.8 pp.1192-1194 | en |
dc.relation.ispartof | TRANSPLANTATION | - |
dc.title | All Chronic Rejection Failures of Kidney Transplants Were Preceded by the Development of Hla Antibodies | en |
dc.type | journal article | en |
dc.relation.pages | 1192-1194 | - |
dc.relation.journalvolume | v.74 | - |
dc.relation.journalissue | n.8 | - |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en_US | - |
item.cerifentitytype | Publications | - |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。