https://scholars.lib.ntu.edu.tw/handle/123456789/194879
標題: | Noninvasive Diagnosis of Aortic Coarctation in Neonates with Patent Ductus Arteriosus | 作者: | LU, CHUN-WEI WANG, JOU-KOU CHANG, CHUNG -I LIN, MING-TAI WU, EN-TING LUE, HUNG-CHI CHEN, YIH-SHARNG CHIU, ING-SH WU, MEI-HWAN |
關鍵字: | Aorta/abnormalities/ultrasonography;Aortic Coarctation/ complications/ diagnosis/physiopathology;Blood Flow Velocity;Blood Pressure;Case-Control Studies;Ductus Arteriosus, Patent/complications/ diagnosis/physiopat | 公開日期: | 2006 | 卷: | v.148 | 期: | n.2 | 起(迄)頁: | 217-221 | 來源出版物: | JOURNAL OF PEDIATRICS | 摘要: | OBJECTIVES: To find a noninvasive method to detect coarctation of the aorta (CoA) in the presence of a patent ductus arteriosus (PDA) in neonates. STUDY DESIGN: From 1994 to 1998, 36 neonates with CoA and PDA confirmed by surgery or cardiac catheterization were studied; another 19 neonates with isolated PDA served as control patients. The prospective study was conducted from 2001 to 2002 on 162 neonates. RESULTS: Among the 36 neonates in the CoA group, 14 patients (39%) had blood pressure discrepancy, 26 patients (72%) had a visualized posterior shelf by echocardiogram, and the ratio of isthmus/descending aorta diameters (I/D ratio) was below 0.64 in 32 patients (89%). None of the control patients had these features. A diagnostic approach was subsequently proposed, according to which a neonate with PDA who fulfilled any of the above features was diagnosed as CoA plus PDA. In the prospective study, the sensitivity and positive predictive values of this method were both 91.7%, whereas the specificity and negative predictive values were both 99.3%. CONCLUSIONS: Echocardiographic measurements of I/D ratio along with the delineation of posterior shelf and a BP discrepancy can satisfactorily identify CoA in the presence of PDA in neonates. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/92636 |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。