https://scholars.lib.ntu.edu.tw/handle/123456789/194919
DC Field | Value | Language |
---|---|---|
dc.contributor | 小兒科 | en |
dc.contributor.author | Huang, Yhu-Chering | en |
dc.contributor.author | Lin, Tzou-Yien | en |
dc.contributor.author | Lien, Rey-In | en |
dc.contributor.author | Chou, Yi-Hong | en |
dc.contributor.author | Kuo, Chii-Yuh | en |
dc.contributor.author | Yang, Peng-Hong | en |
dc.contributor.author | Hsieh, Wu-Shiun | en |
dc.creator | 謝武勳 | zh-tw |
dc.creator | Huang, Yhu-Chering; Lin, Tzou-Yien; Lien, Rey-In; Chou, Yi-Hong; Kuo, Chii-Yuh; Yang, Peng-Hong; Hsieh, Wu-Shiun | en |
dc.date | 2000 | en |
dc.date.accessioned | 2008-12-29T06:09:04Z | - |
dc.date.accessioned | 2018-07-11T17:54:28Z | - |
dc.date.available | 2008-12-29T06:09:04Z | - |
dc.date.available | 2018-07-11T17:54:28Z | - |
dc.date.issued | 2000 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/94811 | - |
dc.description.abstract | We reviewed 62 episodes (from 59 infants) of neonatal candidemia that occurred between January 1994 and June 1999. Except 5 term babies, all infants were premature (median gestational age [GA], 30 weeks) and birth weight was less than 2500 g (median, 1300 g). Most infants had reported risk factors and other neonatal problems. The age at onset of candidemia ranged from 15 to 173 days with a median of 34 days. In addition to catheter removal, all but one infants received antifungal agents and candidemia was eradicated subsequently in 46 episodes (75%). Eighteen infants with 19 episodes ever received fluconazole therapy. Fluconazole was administered as the first line agent in 6 episodes and successfully cleared candidemia in 5 episodes. Fluconazole was used as an alternative agent in an additional 13 episodes after amphotericin B (am B) +/- flucytosine were given for a period without a satisfactory result and eradication of candidemia was achieved in 8 episodes subsequently. All 18 infants tolerated fluconazole well and no withdrawal was required on account of its adverse effect. In contrast, am B alone was administered as the first line agent in 55 episodes and successfully cleared candidemia in 32 episodes (58%). This retrospective analysis suggests that fluconazole appears to be safe in neonates and can be used as an alternative agent in treating neonatal candidemia. A large-scaled prospective study may be needed. | en |
dc.language | en-us | en |
dc.language.iso | en_US | - |
dc.relation | AMERICAN JOURNAL OF PERINATOLOGY v.17 n.8 pp.411-415 | en |
dc.relation.ispartof | AMERICAN JOURNAL OF PERINATOLOGY | - |
dc.subject | fluconazole | en |
dc.subject | neonate | en |
dc.subject | candidemia | en |
dc.subject | INTENSIVE-CARE UNIT | en |
dc.subject | AMPHOTERICIN-B | en |
dc.subject | RANDOMIZED TRIAL | en |
dc.title | Fluconazole Therapy in Neonatal Candidemia | en |
dc.type | journal article | en |
dc.relation.pages | 411-415 | - |
dc.relation.journalvolume | v.17 | - |
dc.relation.journalissue | n.8 | - |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.languageiso639-1 | en_US | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
Appears in Collections: | 醫學系 |
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