https://scholars.lib.ntu.edu.tw/handle/123456789/194938
DC Field | Value | Language |
---|---|---|
dc.contributor | 小兒科 | en |
dc.contributor.author | CHEN, JIMMY PENG-SHENG | en |
dc.contributor.author | LIN, KAI-HSIN | en |
dc.contributor.author | LU, MENG-YAO | en |
dc.contributor.author | LIN, DONG-TSAMN | en |
dc.contributor.author | LIN, KUO-SIN | en |
dc.creator | 陳鵬升;林凱信;盧孟佑;林東燦;林國信 | zh_TW |
dc.creator | CHEN, JIMMY PENG-SHENG;LIN, KAI-HSIN;LU, MENG-YAO;LIN, DONG-TSAMN;LIN, KUO-SIN | en |
dc.date | 2001 | en |
dc.date.accessioned | 2008-12-29T06:11:54Z | - |
dc.date.accessioned | 2018-07-11T17:54:32Z | - |
dc.date.available | 2008-12-29T06:11:54Z | - |
dc.date.available | 2018-07-11T17:54:32Z | - |
dc.date.issued | 2001 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/94830 | - |
dc.description.abstract | OBJECTIVE- To study the prevalence of and risk factors for abnormal glucose tolerance in transfusion-dependent beta- thalassemic patients. RESEARCH DESIGN AND METHODS- A total of 89 transfusion-dependent beta- thalassemic patients were interviewed. Diabetes was previously diagnosed in 14 of them . In the remaining 75 patients, 68 participated in an oral glucose tolerance test. Potential risk factors were identified using the independent t test, X2 test, and Fisher 's exact test. Logistic regression analysis was used to select the independent risk factors that best predicted abnormal glucose tolerance. A two-tailed P value of <0.05 was considered to be statistically significant. RESULTS- The prevalence of impaired glucose tolerance was 8.5% (7 of 82) and that of diabetes was 19. 5% (16 of 82). Presentation with diabetic ketoacidosis was 31.1% (5 of 16) . The risk factors for abnormal glucose tolerance found in transfusion- dependent beta-thalassemic patients were serum ferritin concentration and hepatitis C infection. CONCLUSIONS- The interaction of iron overload and hepatitis C infection worsened the prognosis of thalassemic patients. Aggressive iron-chelation therapy as well as prevention and treatment of hepatitis C infection should be mandatory in managing glucose homeostasis in transfusion-dependent beta- thalassemic patients in Taiwan. | en |
dc.language | en-us | en |
dc.language.iso | en_US | - |
dc.relation | DIABETES CARE v.24 n.5 pp.850-854 | en |
dc.relation.ispartof | DIABETES CARE | - |
dc.subject | IRON-CHELATING THERAPY | en |
dc.subject | INSULIN-RESISTANCE | en |
dc.subject | MARROW TRANSPLANTATION | en |
dc.subject | HEPATITIS-C | en |
dc.subject | SURVIVAL | en |
dc.subject | HYPERINSULINEMIA | en |
dc.subject.classification | [SDGs]SDG3 | - |
dc.title | Abnormal Glucose Tolerance in Transfusion-Dependent Beta- Thalassemic Patients | en |
dc.type | journal article | en |
dc.relation.pages | 850-854 | - |
dc.relation.journalvolume | v.24 | - |
dc.relation.journalissue | n.5 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en_US | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
Appears in Collections: | 醫學系 |
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