https://scholars.lib.ntu.edu.tw/handle/123456789/199873
標題: | An Intervention Trial on Efficacy of Atropine and Multi-Focal Glasses in Controlling Myopic Progression | 作者: | SHIH, YUNG-FENG HSIAO, CHUHSING K. HUNG, POR-TYING LIN, LUKE LONG-KUANG |
關鍵字: | atropine;multi-focal lens;myopi;randomized trial | 公開日期: | 2001 | 卷: | v.79 | 期: | n.3 | 起(迄)頁: | 233-236 | 來源出版物: | ACTA OPHTHALMOLOGICA SCANDINAVICA | 摘要: | Purpose: This randomized clinical trial assessed the treatment effects of atropine and/or multi-focal lenses in decreasing the progression rate of myopia in children. Methods: Two hundred and twenty-seven schoolchildren with myopia, aged from 6 to 13 years, who were stratified based on gender, age and the initial amount of myopia were randomly assigned to three treatment groups: 0.5% atropine with multi-focal glasses, multi-focal glasses, and single vision spectacles, Each subject was followed for at least eighteen months. These results report on the 188 patients available for the follow-up.Results: The mean progression of myopia in atropine with multi-focal glasses group (0.41 D) was significantly less than the multi- focal (1.19 D) and single vision group (1.40 D) (p < 0.0001). But no significant difference was noted between the last two groups (p = 0.44). The progression of myopia was significantly correlated with the increases of axial length (r = 0.65, p = 0.0001), but not with the changes of corneal power (r = -0. 09), anterior chamber depth (r = -0.023), lens thickness (r = -0.08), or intra-ocular pressure (r = -0.008),Conclusion: The 0.5% atropine with multi-focal lenses can slow down the progression rate of myopia. However, multi-focal lenses alone showed no difference in effect compared to control. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/99510 |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。