https://scholars.lib.ntu.edu.tw/handle/123456789/201394
標題: | Detection of Recurrent or Persistent Nasopharyngeal Carcinomas after Radiotherapy with 18-Fluoro-2-Deoxyglucose Positron Emission Tomography and Comparison with Computed Tomography | 作者: | KAO, CHIA-HUNG CHANG, LAI SHENG-PING CHIENG, POON-UNG YEN, RUOH-FANG YEN, TZU-CHEN |
公開日期: | 1998 | 卷: | v.16 | 期: | n.11 | 起(迄)頁: | 3550-5 | 來源出版物: | JOURNAL OF CLINICAL ONCOLOGY | 摘要: | PURPOSE: The effectiveness of positron emission tomography ( PET) with 1 8-fluoro-2-deoxyglucose (FDG) for detecting suspected recurrence of nasopharyngeal carcinomas (NPC) was evaluated and compared with computed tomography (CT). PATIENTS AND METHODS: FDG-PET studies were performed on 36 NPC patients 4 months after radiotherapy. The images were interpreted visually and quantitatively by calculating standardized uptake values(SUVs ). RESULTS: The sensitivity, specificity, and accuracy of visually interpreted FDG-PET images, for differentiation of recurrent or persistent NPC from benign lesions, were 100%, 96%, and 97%, respectively. Cases with recurrent or persistent NPC (1.6 to 5.8) had significantly higher SUVs than cases with benign lesions (0. 8 to 1.5). The sensitivity, specificity, and accuracy of CT for detecting recurrent or persistent NPC were 72%, 88%, and 83%, respectively. CONCLUSION: FDG-PET is a better tool than CT for the detection of recurrent or persistent NPC. Either visual interpretation or SUV can be used to differentiate benign lesions from recurrent or persistent NPC. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/93698 |
顯示於: | 醫學系 |
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