https://scholars.lib.ntu.edu.tw/handle/123456789/201458
標題: | Compare Fdg-Pet and Tc-99m Tetrofosmin Spect to Detect Metastatic Thyroid Carcinoma | 作者: | LIU, FENG-YUAN YEN, RUOH-FANG KAO, CHIA-HUNG |
關鍵字: | 18-fluoro-2-deoxyglucose positron emission tomography (FDG);technetium-99m tetrofosmin single photon emission computed;radioiodine (I-131) whole body scan | 公開日期: | 2003 | 卷: | v.10 | 期: | n.8 | 起(迄)頁: | 835-839 | 來源出版物: | ACADEMIC RADIOLOGY | 摘要: | Rationale and Objectives. The effectiveness of 18-fluoro-2- deoxyglucose (FDG) positron emission tomography (PET) and technetium-99m tetrofosmin ( Tc-99m TF) single photon emission computed tomography (SPECT) of neck and chest was evaluated to detect metastatic lesions in well- differentiated thyroid carcinoma after nearly total thyroidectomy and radioiodine (I-131) treatment who present with elevated serum human thyroglobulin levels but negative I-131 whole body scan. Materials and Methods. Twenty-three patients with differentiated thyroid carcinoma who underwent nearly total thyroidectomy and I-131 treatments were included in this study. Results. All of the 23 patients had negative I-131 whole body scan and elevated human thyroglobulin levels under thyroid-stimulating hormone stimulation. Metastatic lesions were detected by FDG-PET in 20 patients, while Tc-99m TF SPECT revealed metastatic lesions in only 11 of the 20 patients. Both FDG-PET and Tc- 99m TF SPECT failed to demonstrate miliary pulmonary metastases in two of the remaining three patients. The other patient did not show any lesion on FDG-PET, Tc-99m TF SPECT , chest computed tomography, or other imaging techniques. Conclusion. This study demonstrated that FDG-PET is more sensitive than Tc-99m TF SPECT to detect metastatic lesions in differentiated thyroid carcinoma with elevated human thyroglobulin but negative I-131 whole body scan. However, miliary pulmonary metastases could be missed by the both techniques. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/96972 |
顯示於: | 醫學系 |
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