https://scholars.lib.ntu.edu.tw/handle/123456789/201459
標題: | Comparison of Fdg-Pet and Technetium-99m Mibi Spect to Detect Metastatic Cervical Lymph Nodes in Well-Differentiated Thyroid Carcinoma with Elevated Serum Htg but Negative I-131 Whole Body Scan | 作者: | YEN, RUOH-FANG | 關鍵字: | FDG-PET;Tc-99m MIBI SPECT;cervical lymph nodes;well- differentiated thyroid carcinoma | 公開日期: | 2003 | 卷: | v.23 | 期: | n.5B | 起(迄)頁: | 4235-4238 | 來源出版物: | ANTICANCER RESEARCH | 摘要: | The aim of this study was to evaluate the usefulness of 18- fluoro-2- deoxyglucose (FDG) positron emission tomography ( PET) and technetium-99m methoxyisobutylisonitrile (Tc-99m MIBI) single photon emission computed tomography (SPECT) in detecting metastatic cervical lymph nodes (LN) in well- differentiated thyroid carcinoma (DTC) after total thyroidectomy and radioiodine-131 (I-131) treatments inpatients with elevated serum human thyroglobulin (hTg) levels but negative I-131 whole body scan (WBS). Fifteen DTC patients underwent nearly total thyroidectomy and I-131 treatments with cervical LN metastases were included in this study. All subjects had negative I-131 WBS and elevated hTg levels (hTg greater than or equal to 10 muIU/ml) under thyroid-stimulating hormone (TSH) stimulation (TSH greater than or equal to 30 muIU/ml). FDG-PET could detect all of the 15 (100%) patients with metastatic cervical LN, but Tc- 99m MIBI SPECT revealed lesions in only 9 out of 15 (60%) patients (p value < 0.05). This study demonstrated that FDG- PET is more sensitive than Tc-99m MIBI SPECT in detecting metastatic cervical LN in DTC with elevated serum hTg levels but negative I-131 WBS. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/96974 |
顯示於: | 醫學系 |
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