https://scholars.lib.ntu.edu.tw/handle/123456789/201471
標題: | 18-Fluoro-2-Deoxyglucose Positron Emission Tomography in Detecting Residual/Recurrent Nasopharyngeal Carcinomas and Comparison with Magnetic Resonance Imaging | 作者: | YEN, RUOH-FANG HONG, RUEY-LONG PAN, MEI-HSIU WANG, YAO-HONG HUANG, KOU-MOU |
關鍵字: | SQUAMOUS-CELL CARCINOMA;COMBINED PET/CT SCANNER;CONCOMITANT RADIOTHERAPY;F-18 FLUORODEOXYGLUCOSE;HIGH ACCUMULATION;TUMOR RECURRENCE | 公開日期: | 2003 | 卷: | v.98 | 期: | n.2 | 起(迄)頁: | 283-287 | 來源出版物: | CANCER | 摘要: | BACKGROUND. It is known that 18-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) is effective in the early detection of residual/ recurrent nasopharyngeal carcinomas (NPC). To compare FDG-PET with the conventional magnetic resonance imaging (MRI) for the detection of residual/recurrent NPC, the authors studied 67 follow-up cases of patients with NPC using both FDG-PET and MRI. METHODS. From February 1997 to February 2001, 67 NPC patients (14 women, 53 men; age range, 16-67 years; mean age , 46.6 +/- 12.5 years) were recruited. Both FDG-PET and MRI of the head and neck area for each patient were performed at least 4 months ( duration range, 4-70 months; mean, 14 +/- 13.5 months) after radiotherapy or radiotherapy with concurrent chemotherapy. The final diagnosis was confirmed by biopsy or clinical follow-up for at least 6 months. RESULTS. The sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) of FDG-PET images were 100%, 93.4%, 95 .5%, 87.5%, and 100%, respectively. In contrast, the sensitivity, specificity, accuracy, PPV, and NPV of the MRI scans were 61.9%, 43.5%, 49 .3%, 33.3%, and 70.0%, respectively. CONCLUSIONS. The results of the current study suggest that FDG-PET is much more effective than MRI in detecting residual/recurrent NPC. (C) 2003 American Cancer Society. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/96997 |
顯示於: | 醫學系 |
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