https://scholars.lib.ntu.edu.tw/handle/123456789/201526
標題: | Usefulness of (Ti)-T-201 Spect/Ct Relative to F-18-Fdg Pet/Ct in Detecting Recurrent Skull Base Nasopharyngeal Carcinoma | 作者: | YEN, RUOH-FANG TING, LAI-LEI CHENG, MEI-FANG WU, YEN-WEN TZEN, KAI-YUAN HONG, RUEY-LONG |
關鍵字: | (TI)-T-201 SPECT/CT;F-18-FDG PET/CT;nasopharyngeal carcinoma;recurrence;skull base | 公開日期: | 2009 | 卷: | v.31 | 期: | n.6 | 起(迄)頁: | 717-724 | 來源出版物: | HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 摘要: | Background. This study was designed to compare (TI)-T-201 single photon emission computed tomography (SPECT)/CT with 18-fluoro-2-deoxyglucose (F- 18-FDG) PET/CT in diagnosing recurrent skull base nasopharyngeal carcinoma (NPC). Methods . Twenty-seven patients were recruited. Both (TI)-T-201 SPECT/CT and F-18-FDG PET/CT for each patient were performed at least 4 months later after initial therapy. Results. The sensitivity and specificity for (TI)-T-201 SPECT/CT were 66 .7% and 100%, and those for F- 18-FDG PET/CT were 86.7% and 75.0%. Lesion/background ratios were obtained for the 10 lesions that were both SPECT and PET true positive. For the 8 patients with recurrences in nasopharyngeal regions, PET lesion/background ratios were all higher than SPECT lesion/ background ratios. For the 2 patients with intracranial metastases, SPECT lesion/background ratios were higher than PET lesion/background ratios. Conclusion. (TI)-T-201 SPECT/ CT is as effective as F-18-FDG PET/CT in detecting recurrent NPC. For intracranal recurrence, (TI)-T-201 SPECT, because of its high intracranial lesion/background ratio, is probably better than F-18-FDG PET. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/188642 |
顯示於: | 醫學系 |
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