https://scholars.lib.ntu.edu.tw/handle/123456789/202184
標題: | Antimicrobial Resistance in Streptococcus Pneumoniae, Taiwan | 作者: | HSUEH, PO-REN LUH, KWEN-TAY |
關鍵字: | PENICILLIN-RESISTANT;CEPHALOSPORIN-RESISTANT;HAEMOPHILUS- INFLUENZAE;BACTERIAL-MENINGITIS;CLONES;CHILDREN | 公開日期: | 2002 | 卷: | v.8 | 期: | n.12 | 起(迄)頁: | 1487-1491 | 來源出版物: | EMERGING INFECTIOUS DISEASES | 摘要: | Taiwan has one of the highest levels of anti biotic- resistant pneumococcus in the world. Pneumococcal isolates not susceptible to penicillin first appeared in Taiwan in 1986; in 1995 an increase in the prevalence of nonsusceptibility to penicillins, extended-spectrum cephalosporins, trimethoprim-sulfamethoxazole, and macrolides as well as multidrug resistance began to be recognized. With the persistence of antibiotic selective pressure, resistance in some antibiotics reached a high plateau (P-lactam antibiotics) or continued to increase ( macrolides) , while novel resistance (fluoroquinolones) emerged in the last 3 years. Widespread distribution of some novel resistant 23F and 19F clones (and the international epidemic of 23F clones) contributes further to the rapid increase of resistance. Because Streptococcus pneumoniae is a major pathogen that causes community-acquired lower respiratory tract infections and meningitis in adults and children, antibiotic-resistance in this organism is a serious problem. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/103367 |
顯示於: | 醫學系 |
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