https://scholars.lib.ntu.edu.tw/handle/123456789/297323
標題: | Novel terpenoids from the Formosan soft coral Cespitularia hypotentaculata | 作者: | CHANG-FENG DAI | 公開日期: | 2002 | 卷: | 65 | 期: | 10 | 起(迄)頁: | 1429-1433 | 來源出版物: | Journal of Natural Products | 摘要: | Four new cytotoxic diterpenes, cespitularins A-D (1-4), having the verticillane skeleton, a new cytotoxic norditerpene, cesputularin E (5), that possesses a novel norverticillane skeleton, and three new diterpenes, cespitularins F-H (6-8), possessing a novel carbon skeleton named cespitularane, were isolated from the methylene chloride solubles of the Formosan soft coral Cespitularia hypotentaculata. The structures of cespitularins A-H (1-8) were elucidated by 1D and 2D NMR spectral-analysis, and their cytotoxicity against selected cancer cells was measured in vitro. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-0036772613&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/297323 |
DOI: | 10.1021/np020077w | SDG/關鍵字: | cespitularin a; cespitularin b; cespitularin c; cespitularin d; diterpene; terpenoid; unclassified drug; article; carbon nuclear magnetic resonance; coral; cytotoxicity; drug isolation; fractionation; leukemia cell; structure analysis; Animals; Anthozoa; Antineoplastic Agents; Diterpenes; Drug Screening Assays, Antitumor; Molecular Structure; Spectrum Analysis; Tumor Cells, Cultured; Alcyonacea; Anthozoa |
顯示於: | 海洋研究所 |
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