|Title:||Adrenal gland volume after spinal cord injury||Authors:||SHYH-JYE CHEN
|Issue Date:||2002||Journal Volume:||81||Journal Issue:||7||Start page/Pages:||483-488||Source:||American Journal of Physical Medicine and Rehabilitation||Abstract:||
Objective: Spinal cord injury in adult men may result in hypothalamicpituitary-adrenal axis dysfunction. Atrophy of adrenal glands was speculated in these patients. This study was undertaken to clarify the functional-anatomic correlation between adrenal volume and body surface area in subjects with spinal cord injury with impaired adrenal reserve. Design: Twenty male subjects with chronic spinal cord injury with impaired adrenal reserve were identified by adrenocorticotropic hormone stimulation test from a group of 42 subjects. All subjects with spinal cord injury and healthy volunteers underwent computed tomographic imaging with contiguous 3-mm section over adrenal glands for volumetric measurements. Ten pairs of subjects with spinal cord injury and controls with matched height and weight were included in the statistical analysis. Results: Significantly increased relative adrenal volumes were noted among subjects with chronic spinal cord injury and impaired adrenal reserve as compared with the body weight-matched and heightmatched control group. Conclusions: Increased relative adrenal volumes were found after chronic spinal cord injury. Hyperplasia of the zona glomerulosa may be the cause of increased relative adrenal volume after chronic spinal cord injury.
|Appears in Collections:||醫學系|
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