|dc.creator||Chen, R.-J. and Chang, D.-Y. and Yen, M.-L. and Lee, E.F. and Chow, S.-N. and Huang, S.U.-C. and Hsieh, C.-Y.||-|
|dc.description.abstract||Our aim was to identify independent factors that correlated with colposcopically directed biopsy's reliability as a method for diagnosing early cervical cancer. One hundred ninety-one of a total of 2265 patients who had colposcopic examinations because of abnormal Papanicolaou smears were included in this study. These patients had all undergone a hysterectomy after being diagnosed as having cervical intraepithelial neoplasia grade III by colposcopically directed biopsy. By univariate analysis, old age (P = 0.0195), achievement of menopausal status (P = 0.0046), large lesion size (P = 0.0021), and unsatisfactory colposcopy (P = 0.0017) were found to be associated with the nondiagnosis of early cervical cancer. However, multivariate analysis using stepwise logistic regression revealed that large lesion size (P = 0.003) and unsatisfactory colposcopy (P = 0.0008) were the only independent factors that correlated with nondiagnosis. Our findings indicate that in order to reach a clear-cut diagnosis, cases with either unsatisfactory colposcopy or satisfactory colposcopy with large lesions (despite a lack of histologic evidence of invasions) should undergo a diagnostic conization. ? 1995 Academic Press. All rights reserved.||-|
|dc.subject.other||article; cancer diagnosis; colposcopy; correlation function; early cancer; early diagnosis; female; human; human tissue; priority journal; uterine cervix biopsy; uterine cervix cancer; Adult; Biopsy; Cervical Intraepithelial Neoplasia; Cervix Neoplasms; Cervix Uteri; Colposcopy; Evaluation Studies; Female; Human; Middle Age; Neoplasm Invasiveness; Support, Non-U.S. Gov't; Time Factors||-|
|dc.title||Independent clinical factors which correlate with failures in diagnosing early cervical cancer||-|
|Appears in Collections:||醫學系|
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