DC Field | Value | Language |
dc.contributor | 臺大醫院;臺大醫院-內科部;臺大醫院-檢驗醫學部;臺大醫學院;臺大醫學院-內科;臺大醫學院-檢驗醫學科; | en |
dc.contributor.author | Lee, Nan-Yao | en_US |
dc.contributor.author | Lee, Hsin-Chun | en_US |
dc.contributor.author | Huang, Wei-Han | en_US |
dc.contributor.author | Tsui, Ko-Chung | en_US |
dc.contributor.author | CHIA-MING CHANG | en_US |
dc.contributor.author | Lee, Ching-Chi | en_US |
dc.contributor.author | Chen, Po-Lin | en_US |
dc.contributor.author | Wu, Chi-Jung | en_US |
dc.contributor.author | PO-REN HSUEH | en_US |
dc.contributor.author | Ko, Wen-Chien | en_US |
dc.creator | Lee, J.-C. and Lee, N.-Y. and Lee, H.-C. and Huang, W.-H. and Tsui, K.-C. and Chang, C.-M. and Lee, C.-C. and Chen, P.-L. and Wu, C.-J. and Hsueh, P.-R. and Ko, W.-C. | - |
dc.creator | Lee, Jen-Chieh;Lee, Nan-Yao;Lee, Hsin-Chun;Huang, Wei-Han;Tsui, Ko-Chung;Chang, Chia-Ming;Lee, Ching-Chi;Chen, Po-Lin;Wu, Chi-Jung;Hsueh, Po-Ren;Ko, Wen-Chien | en |
dc.creator | 薛博仁 | zh-tw |
dc.date.accessioned | 2018-09-10T09:15:32Z | - |
dc.date.available | 2018-09-10T09:15:32Z | - |
dc.date.issued | 2012 | - |
dc.identifier.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-84859817596&partnerID=MN8TOARS | - |
dc.identifier.uri | http://scholars.lib.ntu.edu.tw/handle/123456789/368948 | - |
dc.description.abstract | Background: The purpose of this study is to delineate clinical characteristics of urosepsis caused by extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae (ESBL-EK) in different clinical settings, with an emphasis on community-acquired infections. Methods: A retrospective study was conducted at two medical centers in Taiwan. From May 2002 to August 2007, clinical data of adults with urosepsis caused by ESBL-EK were collected. Patients were categorized into three groups according to the place of acquisition. Baseline characteristics, microbiological data and clinical outcomes were compared. Results: Ninety-three cases of ESBL-EK urosepsis were included. Their mean age was 69.4 years, and 48.4% were men. Eleven (11.8%), 41 (44.1%), and 41 (44.1%) patients were categorized as having community-acquired, healthcare-associated, and hospital-acquired infections, respectively. Cases of ESBL-EK urosepsis from different settings shared similar characteristics in terms of age, gender, comorbidity and resistance profiles of bacterial strains. Of the bacterial isolates, 75% and 38.7% were resistant to fluoroquinolones and aminoglycosides, respectively. Cases of community-acquired urosepsis had a lower disease severity than those acquired in healthcare facilities or hospitals. Of note, there was no case fatality in 11 cases of community-acquired urosepsis and, in contrast, a crude mortality rate of 41.5% was found among adults with hospital-acquired urosepsis (p < 0.001). Conclusion: A limited number of adults with community-acquired urosepsis caused by ESBL-EK in the present study had a favorable outcome. Nonetheless, clinicians should be cautious of the emergence of urinary tract infections caused by ESBL-producers in the community setting. ? 2011. | en_US |
dc.format.extent | 108 bytes | - |
dc.format.mimetype | text/html | - |
dc.language | en | en |
dc.relation | J. Microbiol. Immunol. Infect., 45(2), 127-133 | en_US |
dc.relation.ispartof | Journal of Microbiology, Immunology and Infection | en_US |
dc.source | AH | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | aminoglycoside antibiotic agent; extended spectrum beta lactamase; quinoline derived antiinfective agent; adult; aged; antibiotic resistance; article; bacterium isolate; clinical feature; disease severity; Escherichia coli; fatality; female; health care facility; hospital; hospital infection; human; Klebsiella pneumoniae; major clinical study; male; mortality; nonhuman; outcome assessment; retrospective study; urinary tract infection; urosepsis; Adult; Aged; Aged, 80 and over; beta-Lactamases; Community-Acquired Infections; Escherichia coli; Escherichia coli Infections; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Prevalence; Retrospective Studies; Sepsis; Taiwan; Urinary Tract Infections | - |
dc.title | Clinical characteristics of urosepsis caused by extended-spectrum beta-lactamase-producing Escherichia coli or Klebsiella pneumonia and their emergence in the community | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.jmii.2011.09.029 | - |
item.fulltext | with fulltext | - |
item.grantfulltext | open | - |
dc.relation.pages | 127-133 | en_US |
dc.relation.journalvolume | 45 | en_US |
dc.relation.journalissue | 2 | en_US |
item.openairetype | journal article | - |
item.fulltext | with fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Civil Engineering | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Laboratory Medicine-NTUH | - |
crisitem.author.orcid | 0000-0002-3804-7547 | - |
crisitem.author.orcid | 0000-0002-7502-9225 | - |
crisitem.author.parentorg | College of Engineering | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
Appears in Collections: | 醫學系
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