https://scholars.lib.ntu.edu.tw/handle/123456789/400498
標題: | Quality of life of breast cancer survivors following breast-conserving therapy versus mastectomy: a multicenter study in Taiwan. | 作者: | Raymond N. Kuo KUO-PIAO CHUNG |
關鍵字: | Breast cancer; Breast-conserving therapy; Mastectomy; Quality-of-care; Quality-of-life | 公開日期: | 十月-2017 | 卷: | 47 | 期: | 10 | 起(迄)頁: | 909-918 | 來源出版物: | Japanese journal of clinical oncology | 摘要: | Background: Breast cancer is the most common female malignancy worldwide. The aim of this study was to investigate the influence of surgical procedures and quality-of-care (QoC) on qualityof- life (QoL) among breast cancer survivors who underwent breast-conserving therapy (BCT) or mastectomy, and to identify provider- and patient-related factors pertaining to QoL. Method: In this cross-sectional study, structured-questionnaires were distributed among breast cancer survivors in 19 hospitals. QoL was evaluated using the European Organization for Research and Treatment of Cancer core questionnaire (EORTC QLQ-C30) and the breast cancer specific module (EORTC QLQ-BR23). QoC is indicated by adherence to the core measures stipulated for the treatment of breast cancer. Multiple regression and hierarchical linear modeling were used for multivariate analysis. Results: A total of 544 female survivors of Stage 0-III breast cancer were included, among whom 217 (39.9%) underwent BCT and 327 (60.1%) underwent mastectomy. Surgical modality does not appear to have a notable impact on any QoL domains except body image; i.e. patients who underwent BCT reported better body image (diff = 11.20, P < 0.001), particularly at 1-5 years after the initial treatment. Independent factors including age, education, employment, marital status, income, chemotherapy, duration since treatment, recurrence status, primary hospital accreditation level and location all appear to be correlated to QoL. Conclusion: Patients with breast cancer should be informed of differences in QoL when discussing treatment options. Furthermore, physicians should recognize that the impact of surgical treatment modality on QoL may vary according to patients' sociodemographic and clinical characteristics. ? The Author 2017. Published by Oxford University Press. All rights reserved. |
URI: | http://europepmc.org/abstract/med/28981734 http://scholars.lib.ntu.edu.tw/handle/123456789/400498 |
DOI: | 10.1093/jjco/hyx099 | SDG/關鍵字: | accreditation; adult; age; aged; Article; body image; breast cancer; cancer chemotherapy; cancer staging; cancer survivor; controlled clinical trial; controlled study; cross-sectional study; educational status; employment; female; human; income; major clinical study; marriage; mastectomy; multicenter study; partial mastectomy; quality of life; structured questionnaire; Taiwan; treatment duration; breast tumor; clinical trial; mastectomy; middle aged; mortality; partial mastectomy; pathology; procedures; psychology; quality of life; questionnaire; survivor; very elderly; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Cross-Sectional Studies; Female; Humans; Mastectomy; Mastectomy, Segmental; Middle Aged; Quality of Life; Surveys and Questionnaires; Survivors; Taiwan |
顯示於: | 健康政策與管理研究所 |
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