https://scholars.lib.ntu.edu.tw/handle/123456789/402422
標題: | Chemopreventive effect of natural dietary compounds on xenobiotic-induced toxicity | 作者: | Wu, J.-C. Lai, C.-S. Tsai, M.-L. Ho, C.-T. Wang, Y.-J. Pan, M.-H. MIN-HSIUNG PAN |
關鍵字: | chemoprevention; environmental pollutants; metabolism; phytochemicals; xenobiotics | 公開日期: | 2017 | 卷: | 25 | 期: | 1 | 起(迄)頁: | 176-186 | 來源出版物: | Journal of Food and Drug Analysis | 摘要: | Contaminants (or pollutants) that affect human health have become an important issue, spawning a myriad of studies on how to prevent harmful contaminant-induced effects. Recently, a variety of biological functions of natural dietary compounds derived from consumed foods and plants have been demonstrated in a number of studies. Natural dietary compounds exhibited several beneficial effects for the prevention of disease and the inhibition of chemically-induced carcinogenesis. Contaminant-induced toxicity and carcinogenesis are mostly attributed to the mutagenic activity of reactive metabolites and the disruption of normal biological functions. Therefore, the metabolic regulation of hazardous chemicals is key to reducing contaminant-induced adverse health effects. Moreover, promoting contaminant excretion from the body through Phase I and II metabolizing enzymes is also a useful strategy for reducing contaminant-induced toxicity. This review focuses on summarizing the natural dietary compounds derived from common dietary foods and plants and their possible mechanisms of action in the prevention/suppression of contaminant-induced toxicity. ? 2016 |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-85009286592&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/402422 |
DOI: | 10.1016/j.jfda.2016.10.019 | SDG/關鍵字: | carotenoid; flavonoid; heptane derivative; natural product; phenol derivative; plant extract; stilbene derivative; xenobiotic agent; antineoplastic agent; xenobiotic agent; chemoprophylaxis; dietary intake; food contamination; food poisoning; human; nonhuman; pollutant; Review; diet; Anticarcinogenic Agents; Diet; Humans; Xenobiotics |
顯示於: | 食品科技研究所 |
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PIIS1021949816301818.pdf | 1.38 MB | Adobe PDF | 檢視/開啟 |
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