|Title:||Pentoxifylline decreases post-operative intra-abdominal adhesion formation in an animal model||Authors:||CHIEN-CHANG LEE
|Keywords:||Angiogenesis; Collagen deposistin; Fibrinolysis; Fibrosis; Inflammation; Intra-abdominal adhesion formation; Pentoxifylline; Tissue plasminogen activator level||Issue Date:||2018||Publisher:||PEERJ INC||Source:||PeerJ||Abstract:||
Intra-abdominal adhesions develop after nearly every abdominal surgery, commonly causing female infertility, chronic pelvic pain, and small bowel obstruction. Pentoxifylline (PTX) is a methylxanthine compound with immunomodulatory and antifibrotic properties. The aim of this study was to investigate whether PTX can reduce post-operative intra-abdominal adhesion formation via collagen deposition, tissue plasminogen activator (tPA) level, inflammation, angiogenesis, and fibrosis.
|Appears in Collections:||醫學院附設醫院 (臺大醫院)|
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