|Title:||The relationship of anti-phospholipase A2 receptor antibody and C5a complement with disease activity and short-term outcome in idiopathic membranous nephropathy||Authors:||Chi, Jyun Ni
Wu, Ching Fang
Fu, Tian Yi
Chiang, Wen Chih
Chen, Yung Ming
Wu, Ming Shiou
|Keywords:||Anti-phospholipase A2 receptor antibody; C5a; Disease activity; Membranous nephropathy; Prognosis||Issue Date:||10-Jan-2019||Source:||Journal of the Formosan Medical Association = Taiwan yi zhi||Abstract:||
The binding of anti-phospholipase A2 receptor (anti-PLA2R) antibody to podocyte and complement activation is the mechanisms of idiopathic membranous nephropathy (IMN). C5a, a complement activation end product, is a strong inflammatory cell stimulator and can influence the behavior of T cells and dendritic cells. This study examined the etiology-disease relationship and significance of auto-antibody and C5a with short-term remission.
|Appears in Collections:||醫學系|
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