|Title:||Acoustic waves improves retroviral transduction in human retinal stem cells||Authors:||Peng, Chi-Hsien
|Keywords:||Gene transfection; Photoreceptor; Retinal stem cells; Retrovirus; Ultrasound standing waves||Issue Date:||Sep-2018||Publisher:||ELSEVIER TAIWAN||Source:||Journal of the Chinese Medical Association : JCMA||Journal Volume:||81||Journal Issue:||9||Start page/Pages:||830||Abstract:||
The plasticity of retinal stem cells (RSCs), a type of cells that can differentiate into neuron cells and photoreceptor cells, endows them with potential therapeutic properties that can be applied to regenerative medicine. Gene modification of these stem cells before trans-differentiation and transplantation enhances their survival and increases their therapeutic function. The different ways to effectively deliver gene into RSCs are still discussed. This study aimed to use the acoustic waves to improve the efficacy of gene delivery for RSCs.
|Appears in Collections:||醫學院附設醫院 (臺大醫院)|
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