https://scholars.lib.ntu.edu.tw/handle/123456789/414041
標題: | Characterization and prebiotic activity of aqueous extract and indigestible polysaccharide from anoectochilus formosanus | 作者: | Yang L.-C. Lin W.-C. Lu T.-J. |
關鍵字: | Anoectochilus formosanus;calcium absorption;prebiotic;type II arabinogalactan | 公開日期: | 2012 | 卷: | 60 | 期: | 35 | 起(迄)頁: | 8590-8599 | 來源出版物: | Journal of Agricultural and Food Chemistry | 摘要: | Anoectochilus formosanus (Orchidaceae) is a folk medicine in Asia. This study investigated the in vivo and in vitro prebiotic effects of an aqueous extract of A. formosanus (SAEAF) and of an indigestible polysaccharide (AFP) isolated from SAEAF. Chemical analyses showed AFP was mainly composed of arabinogalactan type II (AG-II), with an average molecular weight of 29 kDa. Following 4 weeks of oral administration to rats, SAEAF exhibited prebiotic effects including a decrease in cecum pH and increases of calcium absorption and fecal bifidobacteria. Furthermore, through a bioactivity-guided separation strategy, AFP was proven to be a bifidogenic component in vitro fecal strains fermentation and in vivo administration to mice. In RT-PCR analysis of Bifidobacterium, AFP increased the expression of ABC transporter related to nutrient uptake. Thus, AFP, a polysaccharide from A. formosanus, was demonstrated to be a prebiotic that has a positive health effect on gut microbiota. ? 2012 American Chemical Society. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/414041 | ISSN: | 00218561 | DOI: | 10.1021/jf3018832 |
顯示於: | 食品科技研究所 |
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