DC 欄位 | 值 | 語言 |
dc.contributor.author | Tang Y. | en_US |
dc.contributor.author | Liu X. | en_US |
dc.contributor.author | Liu X. | en_US |
dc.contributor.author | Li Y. | en_US |
dc.contributor.author | Wu K. | en_US |
dc.contributor.author | Hou X. | en_US |
dc.creator | Hou X.;Wu K.;Li Y.;Liu X.;Liu X.;Tang Y. | - |
dc.date.accessioned | 2019-07-17T04:20:40Z | - |
dc.date.available | 2019-07-17T04:20:40Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 16742052 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/414208 | - |
dc.description.abstract | Light is a crucial environmental signal that promotes photomorphogenesis, the developmental process with a series of light-dependent alterations for plants to adapt various external challenges. Chromatin modification has been proposed to be involved in such light-mediated growth, but the underlying mechanism is still elusive. In this study, we identified four Arabidopsis thaliana Nuclear Factor-YC homologs, NF-YC1, NF-YC3, NF-YC4, and NF-YC9 (NF-YCs), which function redundantly as repressors of light-controlled hypocotyl elongation via histone deacetylation. Obvious etiolation phenotypes are observed in NF-YCs loss-of-function mutant seedlings grown under light conditions, including significant elongated hypocotyls and fewer opened cotyledons. We found that?NF-YCs interact with histone deacetylase HDA15 in the light, co-target the promoters of a set of hypocotyl elongation-related genes, and modulate the levels of histone H4 acetylation on the?associated chromatins, thus repressing gene expression. In contrast, NF-YC-HDA15 complex is dismissed from the target genes in the dark, resulting in increased level of H4 acetylation and?consequent etiolated growth. Further analyses revealed that transcriptional repression activity of NF-YCs on the light-controlled hypocotyl elongation partially depends on the deacetylation activity of HDA15, and loss of HDA15 function could rescue?the short-hypocotyl phenotype of NF-YCs overexpression plants. Taken together, our results indicate that NF-YC1, NF-YC3, NF-YC4, and NF-YC9 function as transcriptional co-repressors by interacting with HDA15 to inhibit hypocotyl elongation in photomorphogenesis during the early seedling stage. Our findings highlight that NF-YCs can modulate plant development in response to environmental cues via epigenetic regulation. ? 2017 The Author | en_US |
dc.language | English | - |
dc.relation.ispartof | Molecular Plant | en_US |
dc.subject | histone deactylation | en_US |
dc.subject | hypocotyl elongation | en_US |
dc.subject | NF-YC | en_US |
dc.subject | photomorphogenesis | en_US |
dc.title | Arabidopsis NF-YCs Mediate the Light-Controlled Hypocotyl Elongation via Modulating Histone Acetylation | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.molp.2016.11.007 | - |
dc.identifier.doi | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85009460295&doi=10.1016%2fj.molp.2016.11.007&partnerID=40&md5=92f3d28a8f97a9f13bf1558983a73cc9 | - |
dc.identifier.pmid | 27876642 | - |
dc.identifier.scopus | 2-s2.0-85009460295 | - |
dc.identifier.url | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85009460295&doi=10.1016%2fj.molp.2016.11.007&partnerID=40&md5=92f3d28a8f97a9f13bf1558983a73cc9 | - |
dc.relation.pages | 260-273 | en_US |
dc.relation.journalvolume | 10 | en_US |
dc.relation.journalissue | 2 | en_US |
item.cerifentitytype | Publications | - |
item.fulltext | with fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | open | - |
crisitem.author.dept | Plant Biology | - |
crisitem.author.dept | Life Science | - |
crisitem.author.dept | Ph. D. Program In Plant Biotechnology Development Of Industry-academia Cooperation | - |
crisitem.author.orcid | 0000-0002-5791-3594 | - |
crisitem.author.parentorg | College of Life Science | - |
crisitem.author.parentorg | College of Life Science | - |
crisitem.author.parentorg | College of Life Science | - |
顯示於: | 植物科學研究所
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