https://scholars.lib.ntu.edu.tw/handle/123456789/415263
DC Field | Value | Language |
---|---|---|
dc.contributor.author | JEAN-SAN CHIA | en_US |
dc.contributor.author | Du, Jia-Ling | en_US |
dc.contributor.author | Hsu, Wei-Bin | en_US |
dc.contributor.author | ANDY SUN | en_US |
dc.contributor.author | CHUN-PIN CHIANG | en_US |
dc.contributor.author | WON-BO WANG | en_US |
dc.creator | Jean-San Chia;Du, Jia-Ling;Hsu, Wei-Bin;Andy Sun;Chun-Pin Chiang;Won-Bo Wang | - |
dc.date.accessioned | 2019-07-26T03:47:37Z | - |
dc.date.available | 2019-07-26T03:47:37Z | - |
dc.date.issued | 2010-04-30 | - |
dc.identifier.issn | 1471-2407 | - |
dc.identifier.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-77951581527&partnerID=MN8TOARS | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/415263 | - |
dc.description.abstract | Advanced cancer is a multifactorial disease that demands treatments targeting multiple cellular pathways. Chinese herbal cocktail which contains various phytochemicals may target multiple dys-regulated pathways in cancer cells and thus may provide an alternative/complementary way to treat cancers. Previously we reported that the Chinese herbal cocktail Tien-Hsien Liguid (THL) can specifically induce apoptosis in various cancer cells and have immuno-modulating activity. In this study, we further evaluated the anti-metastatic, anti-angiogenic and anti-tumor activities of THL with a series of in vitro and in vivo experiments. | en_US |
dc.language.iso | en | en_US |
dc.publisher | BMC | en_US |
dc.relation.ispartof | BMC cancer | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | antineoplastic agent; gelatinase A; gelatinase B; herbaceous agent; hypoxia inducible factor 1alpha; mitogen activated protein kinase 1; mitogen activated protein kinase 3; tien hsien; unclassified drug; urokinase; vasculotropin A; antineoplastic agent; gelatinase A; gelatinase B; herbaceous agent; HIF1A protein, human; hypoxia inducible factor 1alpha; mitogen activated protein kinase 1; mitogen activated protein kinase 3; tien hsien liquid; tien-hsien liquid; urokinase; vasculotropin A; VEGFA protein, human; animal experiment; animal model; antiangiogenic activity; apoptosis; article; breast cancer; cancer cell; cancer inhibition; cell invasion; cell migration; controlled study; endothelium cell; female; human; human cell; lung metastasis; metastasis inhibition; mouse; nonhuman; protein expression; protein phosphorylation; animal; Bagg albino mouse; breast tumor; cancer invasion; cell motion; colon tumor; dose response; drug effect; drug screening; lung tumor; metabolism; metastasis; mouse mutant; neovascularization (pathology); nonobese diabetic mouse; pathology; time; tumor cell line; tumor volume; vascularization; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelial Cells; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Neovascularization, Pathologic; Time Factors; Tumor Burden; Urokinase-Type Plasminogen Activator; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | - |
dc.title | Inhibition of metastasis, angiogenesis, and tumor growth by Chinese herbal cocktail Tien-Hsien Liquid | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1186/1471-2407-10-175 | - |
dc.identifier.pmid | 20429953 | - |
dc.identifier.scopus | 2-s2.0-77951581527 | - |
dc.identifier.isi | WOS:000278365300002 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/77951581527 | - |
dc.relation.journalvolume | 10 | en_US |
dc.relation.journalissue | 1 | en_US |
item.fulltext | no fulltext | - |
item.cerifentitytype | Publications | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
crisitem.author.dept | Clinical Dentistry | - |
crisitem.author.dept | Clinical Medicine | - |
crisitem.author.dept | Oral Biology | - |
crisitem.author.dept | Microbiology | - |
crisitem.author.dept | Dentistry-NTUH | - |
crisitem.author.dept | School of Dentistry | - |
crisitem.author.dept | Oral Biology | - |
crisitem.author.dept | Microbiology | - |
crisitem.author.orcid | 0000-0002-5431-0712 | - |
crisitem.author.orcid | 0000-0002-4912-5424 | - |
crisitem.author.orcid | 0000-0002-6190-7162 | - |
crisitem.author.orcid | 0000-0002-0135-8958 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
Appears in Collections: | 口腔生物科學研究所 |
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