https://scholars.lib.ntu.edu.tw/handle/123456789/417091
標題: | Bioactive diterpenes from Callicarpa longissima | 作者: | Liu Y.-W. Cheng Y.-B. Liaw C.-C. Chen C.-H. JIH-HWA GUH Hwang T.-L. Tsai J.-S. WON-BO WANG Shen Y.-C. |
公開日期: | 2012 | 卷: | 75 | 期: | 4 | 起(迄)頁: | 689-693 | 來源出版物: | Journal of Natural Products | 摘要: | Investigation of the leaves and twigs of Callicarpa longissima resulted in the isolation of four new compounds (1-4), callilongisins A-D, and five known compounds, ursolic acid, 3-oxoanticopalic acid, (E)-6β-hydroxylabda-8(17), 13-dien-15-oic acid, 5-hydroxy-3,6,7,4′-tetramethoxyflavone, and artemetin. Compounds 1-3 are 3,4-seco-abietane-type diterpenoids, and compound 4 is an analogue of a labdenoic-type diterpene. The structure of compound 1 was confirmed by X-ray crystallographic analysis. Cytotoxicity against a human prostate cancer cell line (PC3) and anti-inflammatory activities of the isolated compounds were evaluated. ? 2012 The American Chemical Society and American Society of Pharmacognosy. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84860340216&doi=10.1021%2fnp200932k&partnerID=40&md5=05106cd7aa6605c1530ec944f8b7dc80 https://scholars.lib.ntu.edu.tw/handle/123456789/417091 |
ISSN: | 0163-3864 | DOI: | 10.1021/np200932k | SDG/關鍵字: | 13 dien 15 oic acid; 3 oxoanticopalic acid; 3,4 seco abietane; 5 hydroxy 3,6,7,4 tetramethoxyflavone; 6beta hydroxylabda 8; artemetin; Callicarpa longissima extract; callilongisin A; callilongisin B; callilongisin C; callilongisin D; diterpene; plant extract; unclassified drug; ursolic acid; antiinflammatory activity; article; Callicarpa longissima; cancer cell culture; cytotoxicity; drug activity; drug isolation; drug structure; human; human cell; medicinal plant; nonhuman; prostate cancer; X ray crystallography; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Callicarpa; Crystallography, X-Ray; Diterpenes; Drug Screening Assays, Antitumor; Humans; Male; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves |
顯示於: | 微生物學科所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。