https://scholars.lib.ntu.edu.tw/handle/123456789/417244
標題: | Genotypes of hepatitis C virus in chronic liver disease in Taiwan | 作者: | CHIEN-HUNG CHEN JIN-CHUAN SHEU JIN-TOWN WANG GUAN-TARN HUANG PEI-MING YANG Lee, Hsuan-Shu Lee, Cha-Ze DING-SHINN CHEN |
公開日期: | 1994 | 卷: | 44 | 期: | 3 | 起(迄)頁: | 234-236 | 來源出版物: | Journal of Medical Virology | 摘要: | The genotypes of hepatitis C virus (HCV) infection in 81 patients with liver cirrhosis (LC) or hepatocellular carcinoma (HCC) were investigated by the polymerase chain reaction using type?specific primers. All the patients were positive for HCV RNA in the serum. Forty?two patients had LC with HCC, while the remaining 39 patients had LC without HCC. Genotype II was detected in 47 samples (58.0%), type III in 6 samples (7.4%), and type IV in 4 (6.2%). No evidence of genotype I was found. Mixed infection was detected in 11 samples (13.6%). The prevalence of genotype II in LC with HCC patients (69.0%) was significantly higher (P < 0.05) than in the LC without HCC patients (46.2%). It is concluded that genotype II is the most predominant type in patients with LC or HCC in Taiwan, and is found more frequently in patients who had LC with HCC than in those who had LC alone. ? 1994 Wiley?Liss, Inc. Copyright ? 1994 Wiley?Liss, Inc., A Wiley Company |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028027553&doi=10.1002%2fjmv.1890440304&partnerID=40&md5=cf6a301bbfdc68f5d4a63071ba98ef46 https://scholars.lib.ntu.edu.tw/handle/123456789/417244 |
ISSN: | 0146-6615 | DOI: | 10.1002/jmv.1890440304 | SDG/關鍵字: | adult; aged; article; chronic liver disease; controlled study; female; genotype; hepatitis c virus; human; liver cell carcinoma; liver cirrhosis; major clinical study; male; polymerase chain reaction; taiwan; Adult; Aged; Aged, 80 and over; Base Sequence; Carcinoma, Hepatocellular; Chronic Disease; Female; Genotype; Hepatitis C; Human; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Male; Middle Age; Molecular Sequence Data; Polymerase Chain Reaction; Support, Non-U.S. Gov't; Taiwan; Hepatitis C virus |
顯示於: | 微生物學科所 |
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