https://scholars.lib.ntu.edu.tw/handle/123456789/417354
標題: | Effects of different types of fluid resuscitation for hemorrhagic shock on splanchnic organ microcirculation and renal reactive oxygen species formation | 作者: | CHUN-YU WU KUANG-CHENG CHAN YA-JUNG CHENG YU-CHANG YEH Chien, Chiang-Ting |
公開日期: | 11-十二月-2015 | 出版社: | BMC | 卷: | 19 | 期: | 1 | 來源出版物: | Critical care (London, England) | 摘要: | Fluid resuscitation is an indispensable procedure in the acute management of hemorrhagic shock for restoring tissue perfusion, particularly microcirculation in splanchnic organs. Resuscitation fluids include crystalloids, hypertonic saline (HTS), and synthetic colloids, and their selection affects the recovery of microcirculatory blood flow and reactive oxygen species (ROS) formation, which is often evident in the kidney, following reperfusion. In this study, the effects of acute resuscitation with 0.9% saline (NS), 3% HTS, 4% succinylated gelatin (GEL), and 6% hydroxyethyl starch (HES) 130/0.4 were compared in a hemorrhagic shock rat model to analyze restoration of microcirculation among various splanchnic organs and the gracilis muscle and reperfusion-induced renal ROS formation. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84956815406&doi=10.1186%2fs13054-015-1135-y&partnerID=40&md5=ca0a30640765fb09576d2a0127474213 https://scholars.lib.ntu.edu.tw/handle/123456789/417354 |
ISSN: | 1466-609X | DOI: | 10.1186/s13054-015-1135-y |
顯示於: | 醫學系 |
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