https://scholars.lib.ntu.edu.tw/handle/123456789/42666
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 雲林分院;精神科 | zh_tw |
dc.contributor.author | HUANG, LUNG-CHENG | en_US |
dc.contributor.author | LIU, CHIH-MIN | en_US |
dc.contributor.author | HWU, HAI-GWO | en_US |
dc.creator | Huang, Lung-Cheng;Liu, Chih-Min;Hwu, Hai-Gwo | - |
dc.date | 2008 | en |
dc.date.accessioned | 2009-11-17T07:25:36Z | - |
dc.date.accessioned | 2018-06-28T13:35:38Z | - |
dc.date.available | 2009-11-17T07:25:36Z | - |
dc.date.available | 2018-06-28T13:35:38Z | - |
dc.date.issued | 2008 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/172919 | - |
dc.description.abstract | Objectives: Tumor necrosis factor alpha (TNF-α) has been related to the pathogenesis of schizophrenia through its involvement in the processes of neurodevelopment and neurodegeneration. We examined the association between the TNF-α -308G/A polymorphism and schizophrenia in Taiwanese samples. Methods : The association analysis was performed using both a case- control and a family- based association design. The case- control sample comprised 124 patients and 119 controls; the family-based sample included 80 parent-offspring trio families. Results: No signifi cant difference was found in genotype or allele frequencies between patients with schizophrenia and controls. No signifi cant transmission distortion of the polymorphism was found in the family sample. Conclusion: Our results suggest that -308 G/A polymorphism in the TNF-α gene does not confer increased susceptibility to schizophrenia in this population of Han Chinese ethnicity from Taiwan. | en_US |
dc.format | application/pdf | en |
dc.format.extent | 338238 bytes | - |
dc.format.mimetype | application/pdf | - |
dc.language | en | en |
dc.language.iso | en_US | en_US |
dc.relation | 台灣精神醫學 v.22 n.2 pp.141-147 | en_US |
dc.relation.ispartof | 台灣精神醫學,v.22 | en_US |
dc.subject | 關聯研究 | en_US |
dc.subject | 單核酸多型性 | en_US |
dc.subject | 精神分裂症 | en_US |
dc.subject | association | en_US |
dc.subject | polymorphism | en_US |
dc.subject | schizophrenia | en_US |
dc.subject | tumor necrosis factor alpha | en_US |
dc.title | A Negative Study of the Association between Tumor Necrosis Factor Alpha-308G/A Polymorphism and Schizophrenia among Taiwanese Patients | en_US |
dc.relation.pages | 141-147 | en_US |
dc.relation.journalissue | n.2 | en_US |
dc.identifier.uri.fulltext | http://ntur.lib.ntu.edu.tw/bitstream/246246/172919/1/66.pdf | - |
item.languageiso639-1 | en_US | - |
item.grantfulltext | open | - |
item.fulltext | with fulltext | - |
crisitem.author.dept | Psychiatry | - |
crisitem.author.dept | Psychiatry-NTUH | - |
crisitem.author.dept | Brain and Mind Sciences | - |
crisitem.author.dept | Psychiatry | - |
crisitem.author.dept | Psychiatry-NTUH | - |
crisitem.author.dept | Epidemiology and Preventive Medicine | - |
crisitem.author.dept | Psychology | - |
crisitem.author.dept | Neurobiology and Cognitive Science Center | - |
crisitem.author.orcid | 0000-0001-7016-8990 | - |
crisitem.author.orcid | 0000-0002-2582-2807 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Science | - |
crisitem.author.parentorg | Others: University-Level Research Centers | - |
顯示於: | 心理學系 |
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